Results 41 to 50 of about 430,076 (284)

Human serum RNase-L level is inversely associated with metabolic syndrome and age

Cardiovascular Diabetology, 2017
Background Ribonuclease-L (RNase-L) was known to be a ubiquitous enzyme involved in several cellular functions, especially innate immunity. It was recently shown to participate in adipogenesis in rodents.
Yi-Ting Wang, Ping-Huei Tseng, Chi-Ling Chen, Der-Sheng Han, Yu-Chiao Chi, Fen-Yu Tseng, Wei-Shiung Yang   +6 more
doaj   +1 more source

RNase P RNA‐mediated cleavage [PDF]

IUBMB Life, 2009
AbstractMetal(II)‐induced hydrolysis of RNA produce products with 5′‐hydroxyls and 2′;3′‐cyclic phosphates at the ends. Ribozymes are RNA molecules that act as catalysts. Some ribozymes that cleave RNA also generate 5′‐hydroxyls and 2′;3′‐cyclic phosphates whereas others produces 5′‐phosphates and 3′‐hydroxyls at the ends of the cleavage products ...
Leif A. Kirsebom, Stefan Trobro
openaire   +4 more sources

Antisense-Inhibition der bakteriellen RNase P [PDF]

, 2005
Ziel der vorliegenden Arbeit war die in vitro- und in vivo-Inhibition bakterieller RNase P mit Antisense-Oligonukleotiden (AS-ON). RNase P ist ein essentielles Ribonukleoproteinenzym, das in allen drei Reichen des Lebens für die Reifung der ptRNAs ...
Grügelsiepe, Heike, Hartmann, Roland K., (Prof. Dr.)   +1 more
core   +1 more source

Evolution and thermodynamics of the slow unfolding of hyperstable monomeric proteins

BMC Evolutionary Biology, 2010
Background The unfolding speed of some hyperthermophilic proteins is dramatically lower than that of their mesostable homologs. Ribonuclease HII from the hyperthermophilic archaeon Thermococcus kodakaraensis (Tk-RNase HII) is stabilized by its remarkably
Koga Yuichi, Chon Hyongi, You Dong-Ju, Tadokoro Takashi, Mukaiyama Atsushi, Okamoto Tomohiro, Okada Jun, Takano Kazufumi, Kanaya Shigenori   +8 more
doaj   +1 more source

RNase MRP and RNase P share a common substrate

Nucleic Acids Research, 1993
RNase MRP is a site-specific ribonucleoprotein endoribonuclease that processes RNA from the mammalian mitochondrial displacement loop containing region. RNase P is a site-specific ribonucleoprotein endoribonuclease that processes pre-tRNAs to generate their mature 5'-ends.
Walter Rossmanith, Thomas Potuschak, Robert Karwan   +2 more
openaire   +4 more sources

Comparative Analysis of Ribonuclease P RNA of the Planctomycetes [PDF]

, 2004
The planctomycetes, order Planctomycetales, are a distinct phylum of domain Bacteria. Genes encoding the RNA portion of ribonuclease P (RNase P) of some planctomycete members were sequenced and compared with existing database planctomycete sequences ...
Altman, Altman, Brochier, Brown, Brown, Brown, Butler, Christian, Condon, Derakshani, Deutscher, Di Giulio, Embley, Felsenstein, Frank, Franzmann, Fuerst, Fuerst, Garrity, Giovannoni, Glöckner, Green, Guerrier-Takada, Haas, Haas, Haas, Hancock, Harris, Harris, Herrmann, Hugenholtz, Jeffares, John A. Fuerst, Kirsebom, Kuypers, Liesack, Liesack, Lindsay, Lindsay, Maeda, Margaret K. Butler, Massire, Massire, Nicholas, Oh, Pace, Pitulle, Schlesner, Schlesner, Schlesner, Schmid, Schön, Sinninghe Damsté, Strous, Vergin, Vioque, Walter, Wang, Woese, Yoon, Zahler, Zuker   +61 more
core   +1 more source

Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location

BMC Genomics, 2002
Background Members of the ribonuclease III superfamily of double-stranded(ds)-RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells. A human RNase III orthologue has been implicated in
Nicholson Rhonda H, Fortin Kristine R, Nicholson Allen W   +2 more
doaj   +1 more source

Phosphatidic acid counteracts S-RNase signaling in pollen by stabilizing the actin cytoskeleton [PDF]

, 2018
S-RNase is the female determinant of self-incompatibility (SI) in pear (Pyrus bretschneideri). After translocation to the pollen tube, S-RNase degrades rRNA and induces pollen tube death in an S-haplotype-specific manner. In this study, we found that the
Chen, Jianqing, De Graaf, Barend H. J., Jiao, Huijun, Tang, Chao, Wang, Peng, Wu, Juyou, Zhang, Hao, Zhang, Shaoling   +7 more
core   +1 more source

Modeling the Thermoproteaceae RNase P RNA [PDF]

RNA Biology, 2012
The RNA component of the RNase P complex is found throughout most branches of the tree of life and is principally responsible for removing the 5' leader sequence from pre-tRNA transcripts during tRNA maturation. RNase P RNA has a number of universal core features, however variations in sequence and structure found in homologs across the tree of life ...
Todd M. Lowe, Patricia P. Chan, James W. Brown   +2 more
openaire   +3 more sources

Modular Architecture of Bacterial RNase P Ribozymes as a Structural Platform for RNA Nanostructure Design

CHIMIA, 2018
Ribonuclease P (RNase P) is a class of enzymes involved in the processing of precursor tRNAs to remove their 5'-leader sequences. Ribonuclease P enzymes are classified into two completely distinct classes, i.e.
Yuri Nozawa, Megumi Hagihara, Shigeyoshi Matsumura, Yoshiya Ikawa   +3 more
doaj   +1 more source