Results 21 to 30 of about 21,290,096 (239)

Membrane recognition and dynamics of the RNA Degradosome [PDF]

open access: yes, 2015
RNase E, which is the central component of the multienzyme RNA degradosome, serves as a scaffold for interaction with other enzymes involved in mRNA degradation including the DEAD-box RNA helicase RhlB.
Luisi, Ben   +48 more
core   +2 more sources

mRNA degradation and maturation in prokaryotes: the global players

open access: yesBiomolecular Concepts, 2011
The degradation of messenger RNA is of universal importance for controlling gene expression. It directly affects protein synthesis by modulating the amount of mRNA available for translation. Regulation of mRNA decay provides an efficient means to produce
Laalami Soumaya, Putzer Harald
doaj   +1 more source

Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.

open access: yesPLoS Biology, 2014
DNA repair mechanisms are essential for preservation of genome integrity. However, it is not clear how DNA are selected and processed at broken ends by exonucleases during repair pathways.
Yu-Yuan Hsiao   +4 more
doaj   +1 more source

Endophytic Bacillus spp. as a Prospective Biological Tool for Control of Viral Diseases and Non-vector Leptinotarsa decemlineata Say. in Solanum tuberosum L.

open access: yesFrontiers in Microbiology, 2020
Viral diseases and their damage causing significant loss to economically important crops have increased by several folds during the last decade. All the conventional approaches are not able to eradicate the viral infection.
Antonina Sorokan   +10 more
doaj   +1 more source

Transcriptome-wide analyses of 5'-ends in RNase J mutants of a gram-positive pathogen reveal a role in RNA maturation, regulation and degradation.

open access: yesPLoS Genetics, 2014
RNA decay and maturation have in recent years been recognised as major regulatory mechanisms in bacteria. In contrast to Escherichia coli, the Firmicute (Gram-positive) bacteria often do not encode the well-studied endonuclease RNase E, but instead rely ...
Patrick Linder   +2 more
doaj   +1 more source

A nitric oxide regulated small RNA controls expression of genes involved in redox homeostasis in Bacillus subtilis. [PDF]

open access: yesPLoS Genetics, 2015
RsaE is the only known trans-acting small regulatory RNA (sRNA) besides the ubiquitous 6S RNA that is conserved between the human pathogen Staphylococcus aureus and the soil-dwelling Firmicute Bacillus subtilis.
Sylvain Durand   +9 more
doaj   +1 more source

A Novel Fully Human Antitumor ImmunoRNase Targeting ErbB2-Positive Tumors [PDF]

open access: yes, 2010
A second generation anti-ErbB2 ImmunoRNase, called Erb-hcAb-RNase, was obtained by the fusion of Erb-hcAb, a human compact anti-ErbB2 antibody, with human pancreatic ribonuclease (HP-RNase or RNase 1).
Borriello, Marianna
core   +1 more source

CATALYTIC PROPERTIES OF THE EUKARYOTIC EXOSOME [PDF]

open access: yes, 2010
The eukaryotic exosome complex is built around the backbone of a 9‑subunit ring similar to phosporolytic ribonucleases such as RNase PH and polynucleotide phosphorylase (PNPase).
María Eugenia Gas López   +13 more
core   +2 more sources

The RNase J-Based RNA Degradosome Is Compartmentalized in the Gastric Pathogen Helicobacter pylori

open access: yesmBio, 2020
Posttranscriptional regulation is a major level of gene expression control in any cell. In bacteria, multiprotein machines called RNA degradosomes are central for RNA processing and degradation, and some were reported to be compartmentalized inside these
Alejandro Tejada-Arranz   +5 more
doaj   +1 more source

The deduced amino acid sequence alignment for the S-RNase (PcS34-RNase),

open access: yes, 2011
S-RNase (PdoS5-RNase), . S-RNase (PaS1-RNase), . S-RNase (PdS11-RNase), and . S-RNase (PtS8-RNase). The asterisks indicate the five amino acid residues that are different between . S-RNase and . S-RNase. Conserved nucleotides are shown on a darkened
Daniel Potter (52965)   +5 more
core   +1 more source

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