Results 231 to 240 of about 118,581 (310)

Favorable histo-molecular remodeling of pancreatic ductal adenocarcinoma after neoadjuvant FOLFIRINOX followed by high-dose stereotactic body radiotherapy. [PDF]

Br J Cancer
Bouchart C, Azurmendi Senar O, Navez J, Verset L, Boisson A, Hein M, Stosic K, Quertinmont E, Tafciu V, Zhao S, Mas L, D'Haene N, Van Gestel D, Moretti L, Michiels E, Rooman I, Detours V, Bachet JB, Demetter P, Willard-Gallo K, Nicolle R, Arsenijevic T, Van Laethem JL.   +22 more
europepmc   +1 more source

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

Comparative genomic and clinicopathological analysis uncovers contrasting molecular profiles of canine and human thyroid carcinomas. [PDF]

Commun Biol
Das S, Schlemmer SN, Idate R, Lana SE, Regan DP, Thamm DH, Duval DL.   +6 more
europepmc   +1 more source

Comparative Response of Canine and Human Osteosarcoma Tumour Cell Lines to Molecularly Targeted Anticancer Agents at Clinically Relevant Exposures With Analysis of Genomic Biomarkers

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Osteosarcoma (OSA) is a primary bone tumour occurring in children but is also prevalent in large breed dogs. Canine OSA (cOSA) has long been viewed as analogous to human OSA (hOSA) with cOSA serving as a surrogate for development of therapeutic approaches to treat the rarer human form.
Daniel L. Gustafson, Kala A. Early, Maritza A. Morales, Klaudia A. Poplawski, Sunetra Das, Dawn L. Duval   +5 more
wiley   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Experimental Sodalis infection eliminates ancient insect symbiont. [PDF]

Nat Commun
Krüsemer R, Carvalho ASP, Keller J, Vogel H, Dale C, Engl T, Kaltenpoth M.   +6 more
europepmc   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

A human-derived Bacteroides strain attenuates depressive-like behavior in a rat model of social defeat-induced stress. [PDF]

BMC Med
Dothard MI, Caboni M, Norment D, Sigmund N, Allard SM, Gilbert JA, Gavrish E, Al-Ghalith G, Der-Avakian A, Strandwitz P.   +9 more
europepmc   +1 more source

Semaglutide impacts skeletal muscle to a similar extent as caloric restriction in mice with diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend Four weeks of semaglutide treatment causes significant reductions in total body weight, fat mass, lean mass, and grip strength in mice with diet induced obesity. Mice treated with semaglutide lost a greater amount of total body weight and fat mass compared to mice fed fed a calorie matched diet.
S. Jeromson, B. Baranowski, M. Akcan, B. D. Waters, K. Eisner, A. Bellucci, S. Trang, A. Abolhassani, M. A. Tello‐Palencia, A. Schweitzer, B. Stefanska, C. J. Mitchell, David C. Wright   +12 more
wiley   +1 more source

Reconstruction of the transcriptional regulatory networks in the kidney of desert-adapted species. [PDF]

Commun Biol
Alvira-Iraizoz F, Gillard BT, Pauža AG, Lin P, Paterson A, Burger PA, Ali MH, Amor N, Alagaili AN, Adem A, Murphy D, Greenwood MP.   +11 more
europepmc   +1 more source