Oocyte–cumulus cell interaction: a key factor in early embryo development
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido +2 more
wiley +1 more source
Mitochondria Dictate Progressive Versus Bimodal Aging of the Mammary Gland. [PDF]
Jenkins EC +6 more
europepmc +1 more source
ABSTRACT Myoblast differentiation is a crucial step of skeletal muscle regeneration and is impaired in the absence of the β2 adrenoceptor (ADRβ2). Since miR‐374b and miR‐326 regulate cell differentiation, this study investigated if ADRβ2 regulates myoblast differentiation via miR‐374b‐5p and miR‐326‐3p. Primary myoblasts from ADRβ2 knockout (β2KO) mice
Tatiana E. Koike +10 more
wiley +1 more source
Correction for Grünig et al., Evolution after whole-genome duplication (WGD) drives phenotypic and transcriptomic divergence more than WGD in an autopolyploid herb. [PDF]
europepmc +1 more source
Proteomic Signatures of Noise‐Induced Hearing Loss in the Mouse Cochlea
ABSTRACT Hearing loss affects over 1.5 billion people worldwide and has substantial social, educational, and economic consequences. Although genetic studies have identified numerous hearing‐loss‐associated genes, the molecular changes accompanying noise‐induced hearing loss (NIHL) remain incompletely understood.
Ana Carla Batissoco +6 more
wiley +1 more source
Polycomb Repressive Complex 2 drives flow-sensitive endothelial states underlying vascular inflammation and disease. [PDF]
Joshi D +14 more
europepmc +1 more source
The hagfish, a jawless early‐branching vertebrate, has very rudimentary eyes that are diminutive and oddly devoid of melanin pigment. Yet, the degenerate hagfish eye grows throughout life and expresses canonical genes of vertebrate retinal development. ABSTRACT Comparative morphology has revealed fascinating structural and organizational differences in
Sarah N. Bradshaw, William T. Allison
wiley +1 more source
Predicting gene essentiality and drug response from preclinical perturbation screens with layered ensemble of autoencoders and predictors. [PDF]
Bodinier B +7 more
europepmc +1 more source
Meningioma microenvironment harbors a rich immune landscape that evolves with biological state. [PDF]
Guo X +24 more
europepmc +1 more source

