Results 71 to 80 of about 179,366 (172)

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

open access: yesJournal of Raman Spectroscopy, Volume 57, Issue 9, Page 1554-1564, September 2026.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira   +3 more
wiley   +1 more source

First Description of an RND-Type Multidrug Efflux Pump in Achromobacter xylosoxidans, AxyABM [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2011
ABSTRACT Achromobacter xylosoxidans is an emerging pathogen in cystic fibrosis patients. The multidrug resistance of these bacteria remains poorly understood. We have characterized in a clinical strain the first resistance-nodulation-cell division (RND)-type multidrug efflux pump in this species: AxyABM.
Bador, Julien   +6 more
openaire   +3 more sources

Reducing bacterial antibiotic resistance by targeting bacterial metabolic pathways and disrupting RND efflux pump activity

open access: yesIberoamerican Journal of Medicine, 2022
Antibiotic resistance is a significant issue for the medical community, worldwide. Many bacteria develop drug resistance by utilizing multidrug resistant or MDR efflux pumps that can export antibiotics from bacterial cells.
Tatiana Hillman
doaj   +1 more source

Genomic Insights Into the Multimetal Resilience and Biofilm‐Templated Nanorod Biosynthesis of Stenotrophomonas bentonitica BII‐R7: Bioremediation and Green Nanotechnology Implications

open access: yesMicrobial Biotechnology, Volume 19, Issue 9, September 2026.
Biofilm extracellular polymeric substances (EPS) in Stenotrophomonas bentonitica BII‐R7 direct the formation of crystalline trigonal selenium nanorods. Comparative genomics identifies a unique genetic toolkit underpinning EPS composition and metal resilience, positioning this strain as a platform for bioremediation and green nanomaterial synthesis ...
Eduardo Perez‐Muelas   +6 more
wiley   +1 more source

Elucidation of the structure and molecular mechanism of the tripartite multidrug efflux pumps in the Gram-negative pathogens: Vibrio cholerae and Neisseria gonorrhoeae [PDF]

open access: yes, 2006
In bacteria, multidrug efflux systems have been identified as significant determinants of resistance recently. These resistance pumps are widely distributed in bacterial species and many pathogenic bacteria posses them, which play an important role in ...
Du, Dijun
core  

ROLE OF RND-EFFLUX PUMP IN LEVOFLOXACIN RESISTANCE AMONG ACINETOBACTER BAUMANNII

open access: yesIRAQI JOURNAL OF AGRICULTURAL SCIENCES, 2022
In this study out of 130 different clinical specimens, 70 Acinetobacter baumannii were collected from hospitalized patients. Then; all the isolates were characterized using biochemical tests and confirmed by using the Vitek II compact system. All isolates of Acinetobacter baumannii were subjected to the disc diffusion method to determine it's a ...
Ali M. A., S.S. Mahmood
openaire   +2 more sources

Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome

open access: yesBMC Microbiology, 2006
Background Burkholderia cenocepacia is recognized as opportunistic pathogen that can cause lung infections in cystic fibrosis patients. A hallmark of B.
Manina Giulia   +6 more
doaj   +1 more source

Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump.

open access: yesPLoS ONE, 2020
The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Kamil Górecki, Megan M McEvoy
doaj   +1 more source

Revisiting Burn Wound Infections: A Comprehensive Review on the Dual Potential of Phages and Probiotics Against Acinetobacter baumannii

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 16, August 2026.
Effect Probiotics on immune system modulation and wound Healing. ABSTRACT Introduction Burn wound infections caused by Acinetobacter baumannii remain a critical clinical challenge due to its extensive multidrug resistance, particularly against carbapenems.
Zeinab Fagheei Aghmiyuni   +6 more
wiley   +1 more source

Overexpression of Efflux Pumps, Mutations in the Pumps’ Regulators, Chromosomal Mutations, and AAC(6′)-Ib-cr Are Associated With Fluoroquinolone Resistance in Diverse Sequence Types of Neonatal Septicaemic Acinetobacter baumannii: A 7-Year Single Center Study

open access: yesFrontiers in Microbiology, 2021
This study investigates susceptibility toward three fluoroquinolones (ciprofloxacin, levofloxacin, moxifloxacin), multiple fluoroquinolone-resistance mechanisms, and epidemiological relationship of neonatal septicaemic Acinetobacter baumannii.
Subhasree Roy   +6 more
doaj   +1 more source

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