The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug Efficacy [PDF]
, 2023 Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections.
Matthew J. Cheesman +9 more
core +1 more source
Bacterial Resistance Toward Antimicrobial Ionic Liquids Mediated by Multidrug Efflux Pumps
Frontiers in Microbiology, 2022 The effective elimination of foodborne pathogens through cleaning and disinfection measures is of great importance to the food processing industry. As food producers rely heavily on disinfectants to control pathogenic bacteria in their facilities, the ...
Tobias Gundolf +5 more
doaj +1 more source
Interplay between three RND efflux pumps in doxycycline-selected strains of Burkholderia thailandensis. [PDF]
PLoS One, 2013 BACKGROUND: Efflux systems are involved in multidrug resistance in most Gram-negative non-fermentative bacteria. We have chosen Burkholderia thailandensis to dissect the development of multidrug resistance phenotypes under antibiotic pressure ...
Biot FV +9 more
europepmc +3 more sources
, 2018 Molecular characterization of efflux RND pumps and their regulators in SCV and mucoid P. aeruginosa isolates.
Carmen Lozano (432027) +3 more
core +1 more source
Defining the interactions between components of RND efflux complexes in Salmonella typhimurium [PDF]
, 2022 Resistance-nodulation-division (RND) efflux pumps contribute to the multidrug resistance of Gram-negative bacteria by exporting clinically relevant antibiotics and preventing them from accumulating at sufficient concentrations.
Alav, Ilyas
core +4 more sources
Role of efflux pumps in reduced susceptibility to tigecycline in Acinetobacter baumannii
New Microbes and New Infections, 2019 Acinetobacter baumannii is an important human pathogen responsible for a various type of infections. These bacterial strains are generally resistant to numerous antibiotics.
S.H. Ardehali +5 more
doaj +1 more source
Developmental Dynamics, EarlyView.Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini +2 more
wiley +1 more source
Crystal structure of the Neisseria gonorrhoeae MtrD inner membrane multidrug efflux pump. [PDF]
PLoS ONE, 2014 Neisseria gonorrhoeae is an obligate human pathogen and the causative agent of the sexually-transmitted disease gonorrhea. The control of this disease has been compromised by the increasing proportion of infections due to antibiotic-resistant strains ...
Jani Reddy Bolla +11 more
doaj +1 more source
Chicken‐linked multidrug‐resistant Campylobacter jejuni infections among Chinese children
iMetaOmics, EarlyView.Campylobacter is a leading cause of pediatric diarrhea, but its genomic epidemiology and antimicrobial resistance in China remain poorly defined. We conducted genomic surveillance of 3492 children with diarrhea in two pediatric hospitals in Zhejiang Province in 2017, 2018, and 2021, combining culture, whole‐genome sequencing, and source‐attribution ...
Dongyan Shao +9 more
wiley +1 more source
RND Efflux Pump Systems in Acinetobacter, with Special Emphasis on theirRole in Quorum Sensing [PDF]
, 2019 Acinetobacter is an important opportunistic, multidrug resistant pathogen causing majority of nosocomial infections worldwide. The multidrug resistance is attributed by a plethora of efflux pumps and the overexpression of the same mediates export of ...
Choi, Chul Hee +2 more
core +1 more source