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Moonshots at Cancer:The Roche Story [PDF]
, 2019 This book tells the story of Hoffmann LaRoche’s engagement with oncology from the 1950s to circa 2010, using the Roche story as a case study for the role of industry in the search for chemical and biological cancer medicines.
Timmermann, Carsten; id_orcid +2 more
core +4 more sources
Heliyon, 2021 Background: Blood-Gas Analyzers (BGAs) are commonly used in parallel with central laboratory analyzers (CLAs). Given the often-divergent results between BGAs and CLAs this study aims to: 1. Determine whether the measurements of potassium (K), sodium (Na),
Kocijancic Marija +2 more
doaj +1 more source
PLoS ONE, 2017 A newly assay, up-converting phosphor technology-based lateral flow (UPT-LF) assay, was developed for rapid and quantitative detection of N-terminal fragment of B-type natriuretic peptide precursor (NT-proBNP), one of the most important serum molecular ...
Xiaoli Yang +9 more
doaj +1 more source
Khyber Medical University Journal, 2022 OBJECTIVE: To compare anion gap estimated through measured and calculated bicarbonate modalities to be used interchangeably in critically ill metabolic acidosis patients.
Sheryar Orakzai +5 more
doaj +1 more source
SPECIFICATION OF LIMITS OF POSSIBLE EXISTENCE OF SATELLITES IN THE GRAVITATIONAL FIELD OF PLANETS
Odessa Astronomical Publications, 2016 It is known that the satellites of the planets may exist in the area, which is bounded on one side by Rocha limit, on the other – Hill sphere. The article deals with the determination of the Rocha limits and Hill sphere of satellites of some planets in ...
S. O. Yasenev, K. O. Radchenko
doaj +1 more source
Dynamical Tide-modified Roche Limit in Eccentric, Asynchronous Binaries
The Astrophysical JournalThe Roche limit, or the threshold separation within which a celestial object (the donor) M cannot remain in a stable configuration due to a companion’s tidal field, has been well established when M is in hydrostatic equilibrium and has synchronous ...
Hang Yu +4 more
doaj +1 more source
AboutOpen, 2021 Although it represents a valid alternative for patients with type 1 diabetes (T1DM) with insufficient glycemic control and/or with recurrent hypoglycemia, insulin pump therapy (Continuous Subcutaneous Insulin Infusion, CSII) in Italy is nowadays still ...
Katherine Esposito +7 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Analytical Performance of the New Sysmex High-Sensitivity Troponin T Assay
DiagnosticsBackground: We evaluated the Sysmex Highly Integrated Single-Cartridge Luminescence Immunoassay System (HISCL) hs-cTnT assay, and compared its performance to the Roche assay, with derivation of 99th-percentile upper reference limits (99% URLs) for ...
Chin Shern Lau +5 more
doaj +1 more source
Technical and regulatory shortcomings of the TaqMan version 1 HIV viral load assay. [PDF]
PLoS ONE, 2012 The lower limit of detection of the original Roche Amplicor HIV plasma viral load (pVL) assay (50 copies/mL) has defined HIV treatment success. The Amplicor assay, however, has been replaced by the Roche TaqMan assay(s).
Chanson J Brumme +7 more
doaj +1 more source