Results 31 to 40 of about 14,218,367 (261)

A contemporary view of work design: how do job complexity and job autonomy shape proactive work behavior through role breadth self-efficacy?

Trakya Üniversitesi İktisadi ve İdari Bilimler Fakültesi E-Dergi
This study investigates how work design influences proactive work behavior (PWB) by considering specific key work characteristics and a motivational mediating variable.
Beynaz Uysal, Cavide Uyargil
doaj   +1 more source

Exploring lifelong learning outcomes among adult learners via goal orientation and information literacy self-efficacy [PDF]

, 2019
This study intends to explore the relationship between goal orientation, information literacy self-efficacy and lifelong learning outcomes of the adult learners.
Kowang, Tan Owee, Adriana Mohd Rizal, Rizal, A. M., Kowang, T. O., Goh Chin Fei, Ping, Lim Lee, Hee, O. C., Ong Choon Hee, Tan Owee Kowang, Fei, Goh Chin, Rizal, Adriana Mohd, Ping, L. L., Hee, Ong Choon, Lim Lee Ping, Fei, G. C.   +14 more
core   +1 more source

Perfectionism, self-efficacy, and aspiration level: Differential effects of perfectionistic striving and self-criticism after success and failure. [PDF]

, 2008
Despite over 15 years of research on multidimensional perfectionism, it is still unclear how different forms of perfectionism are related to self-efficacy, aspiration level, and reactions to success and failure in performance situations.
Stoeber, Joachim, Wood, Kerry V., Hutchfield, Jemeela   +2 more
core   +1 more source

PENGUATAN KESIAPSIAGAAN KEGAWATDARURATAN PADA KOMUNITAS BINAAN PCIM MALAYSIA MELALUI ENTREPRENEURIAL MINDSET BERBASIS METAKOGNISI DAN SELF-EFFICACY [PDF]

ABSTRAKKecelakaan rumah tangga dan kondisi kegawatdaruratan merupakan risiko kesehatan yang sering terjadi dalam kehidupan sehari-hari, namun kesiapsiagaan masyarakat, khususnya komunitas migran, masih terbatas, tidak hanya pada aspek pengetahuan dan ...
Asmara, Maisa Azizah, Apriani, Nuni, Rahmawati, Endah Yuliany, Arissaputra, Rivaldi, Azzahra, Fanny Fatimah   +4 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Emotional and Social Competencies and Perceptions of the Interpersonal Environment of an Organization as Related to the Engagement of IT Professionals.

Frontiers in Psychology, 2015
Diminishing levels of worker productivity and increased employee turnover have become a costly proposition for today’s organizations. Much of the blame for this is a decrease in employee engagement and actual complete disengagement of workers, resulting ...
Linda M Pittenger
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source