Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
BRS Boa Renda and BRS Novo Rumo – new cassava cultivars for starch and flour production
BRS Boa Renda and BRS Novo Rumo are new cassava cultivars with high starch yields, moderate resistance to leaf diseases, and erect plant. BRS Boa Renda yields 25.7 t ha-1 of fresh and 9.5 t ha-1 dry roots, while BRS Novo Rumo yields 22.6 and 8.9 t ha-1 ...
Eder Jorge de Oliveira +7 more
doaj
Adaptability and Stability Analyses of Root Yield and Micronutrient Concentrations in Sweetpotato (<i>Ipomoea batatas</i> [L.] Lam.) Genotypes. [PDF]
Chizhande N +5 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Exogenous Melatonin Increases Root Yield and Its Medicinal Quality of <i>Glycyrrhiza glabra</i> Under Drought Stress. [PDF]
Tian H, Zhou M, Ma M.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Effects of nitrogen, phosphorus, and potassium fertilizers on storage root yield, nutrient use efficiency, and soil nutrient balance of sweetpotato. [PDF]
Zhao Z +7 more
europepmc +1 more source
Impacts of nitrogen fertilization rate on the root yield, starch yield and starch physicochemical properties of the sweet potato cultivar Jishu 25. [PDF]
Duan W, Zhang H, Xie B, Wang B, Zhang L.
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Evaluation of improved cassava genotypes for fresh root yield and yield components in demand creation trial. [PDF]
Onyenali TC +10 more
europepmc +1 more source

