A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Adaptability and Stability Analyses of Root Yield and Micronutrient Concentrations in Sweetpotato (<i>Ipomoea batatas</i> [L.] Lam.) Genotypes. [PDF]
Plant Environ InteractChizhande N +5 more
europepmc +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
BRS Boa Renda and BRS Novo Rumo – new cassava cultivars for starch and flour production
Crop Breeding and Applied BiotechnologyBRS Boa Renda and BRS Novo Rumo are new cassava cultivars with high starch yields, moderate resistance to leaf diseases, and erect plant. BRS Boa Renda yields 25.7 t ha-1 of fresh and 9.5 t ha-1 dry roots, while BRS Novo Rumo yields 22.6 and 8.9 t ha-1 ...
Eder Jorge de Oliveira +7 more
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Exogenous Melatonin Increases Root Yield and Its Medicinal Quality of <i>Glycyrrhiza glabra</i> Under Drought Stress. [PDF]
Plants (Basel)Tian H, Zhou M, Ma M.
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Effects of nitrogen, phosphorus, and potassium fertilizers on storage root yield, nutrient use efficiency, and soil nutrient balance of sweetpotato. [PDF]
BMC Plant BiolZhao Z +7 more
europepmc +1 more source
Impacts of nitrogen fertilization rate on the root yield, starch yield and starch physicochemical properties of the sweet potato cultivar Jishu 25. [PDF]
PLoS One, 2019 Duan W, Zhang H, Xie B, Wang B, Zhang L.
europepmc +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Evaluation of improved cassava genotypes for fresh root yield and yield components in demand creation trial. [PDF]
Front Plant SciOnyenali TC +10 more
europepmc +1 more source