Results 91 to 100 of about 29,549 (204)

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source

Is 0716+714 a superluminal blazar? [PDF]

, 2002
We present an analysis of new and old high frequency VLBI data collected during the last 10 years at 5--22 GHz. For the jet components in the mas-VLBI jet, two component identifications are possible.
Bach, U., Britzen, S., Krichbaum, T. P., Ros, E., Witzel, A., Zensus, J. A.   +5 more
core   +1 more source

Impact of Baseline Nutritional Status, Psychological Health, Fatigue, and Insomnia on Outcomes of Immune Checkpoint Inhibitors in Advanced Non‐Small Cell Lung Cancer: A Retrospective Cohort Study

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 2, February 2026.
ABSTRACT This study investigated the impact of pretreatment nutritional status, psychological health, fatigue, and insomnia on outcomes of immune checkpoint inhibitors (ICIs) monotherapy in patients with advanced non‐small cell lung cancer (NSCLC). A total of 80 patients with stage IV NSCLC were enrolled.
Yu‐Xuan Zhu, Yuan‐Yuan Zhang, Xiu‐Juan Jiang   +2 more
wiley   +1 more source

Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen, Binghua Li, Shengjia Wang, Yongzhong Yao, Zhao Huang, Decai Yu   +5 more
wiley   +1 more source

Importance of Testing for ROS1 Rearrangements in Non-Small Cell Lung Cancer in the Era of Targeted Therapy in a Latin American Country

Cancer Management and Research
Alvaro Osorio,1,2 Liliana Fernandez-Trujillo,2,3 Juan G Restrepo,1,2 Luz F Sua,2,4 Catalina Proaño,5 Valeria Zuñiga-Restrepo2 1Department of Internal Medicine, Oncology Service, Fundación Valle Del Lili, Cali, Colombia; 2Faculty of Health Sciences ...
Osorio A, Fernandez-Trujillo L, Restrepo JG, Sua LF, Proaño C, Zuñiga-Restrepo V   +5 more
doaj  

Different effects of crizotinib treatment in two non‐small cell lung cancer patients with SDC4::ROS1 fusion variants

Thoracic Cancer
The possibility of stratifying patients according to differences in ROS proto‐oncogene 1 (ROS1) fusion partners has been discussed. This study aimed to clarify the clinicopathological differences between two SDC4::ROS1 positive NSCLC cases who had ...
Yuta Ohishi, Yoko Nakanishi, Yukari Hirotani, Atsuko Suzuki, Tomoyuki Tanino, Haruna Nishimaki‐Watanabe, Hiroko Kobayashi, Fumi Nozaki, Sumie Ohni, Xiaoyan Tang, Kentaro Hayashi, Yoshiko Nakagawa, Tetsuo Shimizu, Ichiro Tsujino, Noriaki Takahashi, Yasuhiro Gon, Shinobu Masuda   +16 more
doaj   +1 more source

Genomic Profiling of Pediatric Solid Tumors With a Dual DNA/RNA Panel: JCCG‐TOP2 Study

Cancer Science, Volume 117, Issue 2, Page 522-535, February 2026.
In the JCCG‐TOP2 nationwide pediatric cancer genomic profiling study, 204 patients' tumors and peripheral blood from 50 institutions across Japan were successfully analyzed using a dual DNA/RNA panel. A total of 147 (72%) had potentially actionable findings, including diagnostic, prognostic, and therapeutic findings in 111 (54%), 61 (30%), and 64 (31%),
Kayoko Tao, Takako Yoshioka, Miho Kato, Kazuyuki Komatsu, Shinichi Tsujimoto, Kenichi Sakamoto, Kazuki Tanimura, Minako Sugiyama, Masahiro Sekiguchi, Yoshiko Nakano, Yoshihiro Otani, Yasushi Yatabe, Akihiko Yoshida, Hajime Okita, Junko Hirato, Kenichi Kohashi, Yukichi Tanaka, Shinji Kohsaka, Takashi Kubo, Kuniko Sunami, Makoto Hirata, Shuichi Tsutsumi, Hiroyuki Aburatani, Katsuyoshi Koh, Masahiro Hirayama, Shuhei Karakawa, Yukayo Terashita, Hiroyuki Fujisaki, Takeshi Yagi, Akihiro Yoneda, Shinji Mochizuki, Hiroyuki Shichino, Tatsuya Suzuki, Tetsuya Takimoto, Koichi Ichimura, Chitose Ogawa, Kimikazu Matsumoto, Hitoshi Ichikawa, Motohiro Kato   +38 more
wiley   +1 more source

Real-world studies of crizotinib in patients with ROS1-positive non-small-cell lung cancer: experience from China

Journal of Comparative Effectiveness Research
The treatment of non-small-cell lung cancer (NSCLC) has progressed from histology-oriented cytotoxic therapy to the era of molecular biology-oriented targeted therapy and immunotherapy.
Hua Zhong, Jun Lu, Mengzhao Wang, Baohui Han   +3 more
doaj   +1 more source

Lonely Driver ROS1 [PDF]

Journal of Thoracic Oncology, 2017
Spasenija, Savic, Sacha, Rothschild, Lukas, Bubendorf   +2 more
openaire   +2 more sources

Overexpression of Rosea1 From Snapdragon Enhances Anthocyanin Accumulation and Abiotic Stress Tolerance in Transgenic Tobacco

Frontiers in Plant Science, 2018
The co-expression of Rosea1 (Ros1) and Delila (Del) regulates anthocyanin levels in snapdragon flowers, as well as in tomato, petunia, and tobacco. However, there is little information on how Ros1 expression alone controls anthocyanin regulation and ...
Aung H. Naing, Trinh N. Ai, Ki B. Lim, In J. Lee, Chang K. Kim   +4 more
doaj   +1 more source