Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains [PDF]
Background The role of viral infection in Alzheimer Disease (AD) pathogenesis is an area of great interest in recent years. Several studies have suggested an association between the human roseoloviruses, HHV-6 and HHV-7, and AD.
Tarin M. Bigley+12 more
doaj +11 more sources
Detection of porcine cytomegalovirus, a roseolovirus, in pig ovaries and follicular fluid: implications for somatic cells nuclear transfer, cloning and xenotransplantation [PDF]
Background Porcine cytomegalovirus (PCMV) is a porcine roseolovirus (PCMV/PRV) which is widely distributed in pigs. Transmission of PCMV/PRV in preclinical xenotransplantations was shown to significantly reduce the survival time of the pig transplants in
Sabrina Hansen+7 more
doaj +11 more sources
Structural Models for Roseolovirus U20 And U21: Non-Classical MHC-I Like Proteins From HHV-6A, HHV-6B, and HHV-7 [PDF]
Human roseolovirus U20 and U21 are type I membrane glycoproteins that have been implicated in immune evasion by interfering with recognition of classical and non-classical MHC proteins.
Grant C. Weaver+7 more
doaj +10 more sources
Transcriptomic profiling of thymic dysregulation and viral tropism after neonatal roseolovirus infection [PDF]
IntroductionHerpesviruses, including the roseoloviruses, have been linked to autoimmune disease. The ubiquitous and chronic nature of these infections have made it difficult to establish a causal relationship between acute infection and subsequent ...
Andrei Belean+10 more
doaj +7 more sources
Corrigendum: Structural Models for Roseolovirus U20 And U21: Non-Classical MHC-I Like Proteins From HHV-6A, HHV-6B, and HHV-7 [PDF]
[This corrects the article DOI: 10.3389/fimmu.2022.864898.].
Grant C. Weaver+7 more
doaj +6 more sources
Oral fluid testing can be used to monitor xenotransplant donor herds for porcine cytomegalovirus/roseolovirus status [PDF]
A major concern of xenotransplantation is that donor organs may be a source of pathogens. One pathogen in particular, porcine cytomegalovirus (PCMV), a porcine roseolovirus (PRV), is thought to result in donor organ failure in an immunosuppressed state ...
Susan K. Schommer+10 more
doaj +5 more sources
Presence of porcine cytomegalovirus, a porcine roseolovirus, in wild boars in Italy and Germany. [PDF]
Porcine cytomegalovirus (PCMV), a porcine roseolovirus (PRV) that is closely related to human herpesviruses 6 and 7, is commonly found in commercial pigs.
Hansen S+6 more
europepmc +8 more sources
Disruption of thymic central tolerance by infection with murine roseolovirus induces autoimmune gastritis [PDF]
Bigley et al. show that neonatal murine roseolovirus infection disrupts central tolerance. Autoimmunity arises later, in the absence of ongoing infection.
T. Bigley+5 more
semanticscholar +7 more sources
Human herpes virus type 6 (Orthoherpesviridae: Roseolovirus): features of epidemiology and diagnosis
Human herpes virus 6A and human herpes virus 6B (HHV-6A and HHV-6B) are ubiquitous viruses. The spectrum of clinical manifestations of HHV-6A/B infections is quite wide.
Inara S. Saydullayeva+3 more
doaj +6 more sources
Commentary: Oral fluid testing can be used to monitor xenotransplant donor herds for porcine cytomegalovirus/roseolovirus status [PDF]
Joachim Denner
doaj +4 more sources