Results 71 to 80 of about 27,657 (222)
, 2008 Aims: Type 2 diabetes mellitus (T2DM) is associated with enhanced platelet activation. We conducted a randomised double-blind study to compare the effects of combination metformin and rosiglitazone or metformin and gliclazide therapy on platelet function
Morris, R H K +7 more
core +1 more source
BMEMat, EarlyView.This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu +9 more
wiley +1 more source
Rosiglitazone and Pioglitazone Alter Aromatase Kinetic Properties in Human Granulosa Cells
PPAR Research, 2011 We have previously reported that, in human granulosa cells, thiazolidinediones rosiglitazone and pioglitazone inhibit estrogen synthesis by interfering with androgen binding to aromatase, without an effect on aromatase mRNA or protein expression.
Takako Araki +5 more
doaj +1 more source
A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation
Food Chemistry International, EarlyView.Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee +4 more
wiley +1 more source
CMHX008, a PPARγ partial agonist, enhances insulin sensitivity with minor influences on bone loss
Genes and Diseases, 2018 Traditional thiazolidinediones (TZDs), such as rosiglitazone, are peroxisome proliferator-activated receptor γ (PPARγ) potent agonists that can be used to treat type 2 diabetes but carry unwanted effects, including increased risk for fracture.
Yi Hou +11 more
doaj +1 more source
Rosiglitazone adjunctive therapy improves survival in ECM.
, 2014 Survival curves (A and B) and parasitemia (C and D) for mice infected with PbA and receiving, no treatment (dashed line), 10 mg/kg artesunate plus saline (solid black line), or 10 mg/kg artesunate plus 2.5 mg/kg rosiglitazone (red line).
Cheryl Cui (531361) +8 more
core +1 more source
iMetaOmics, EarlyView.This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian +7 more
wiley +1 more source
Rosiglitazone inhibits endothelial proliferation and angiogenesis
, 2014 Rosiglitazone, an insulin sensitizer, is known to offer beneficial effects in retarding atherosclerotic vascular diseases. Since proliferation and angiogenesis are involved in initiation and plaque instability, two critical steps in the cardiovascular ...
Chou, F.P. +4 more
core +1 more source
Rosiglitazone-induced PPARγ activation promotes intramuscular adipocyte adipogenesis of pig
, 2023 Intramuscular fat (IMF) positively influences various aspects of meat quality, while the subcutaneous fat (SF) has negative effect on carcass characteristics and fattening efficiency.
Zhaolu Wang (2889068) +6 more
core +1 more source
Obesity, EarlyView.ABSTRACT Objective The lipid droplet–associated hydrolase (LDAH) is a lipid droplet–associated protein with an uncharacterized role in human adipose tissue (AT) and obesity; we aimed to investigate its role in human AT and its relevance for childhood obesity.
Claudia Vales‐Villamarín +4 more
wiley +1 more source