Results 21 to 30 of about 1,771 (139)

Aminoquinolines as Translational Models for Drug Repurposing: Anticancer Adjuvant Properties and Toxicokinetic‐Related Features

Journal of Oncology, Volume 2021, Issue 1, 2021., 2021
The indiscriminate consumption of antimalarials against coronavirus disease‐2019 emphasizes the longstanding clinical weapons of medicines. In this work, we conducted a review on the antitumor mechanisms of aminoquinolines, focusing on the responses and differences of tumor histological tissues and toxicity related to pharmacokinetics.
Paulo Michel Pinheiro Ferreira, José Roberto de Oliveira Ferreira, Rayran Walter Ramos de Sousa, Daniel Pereira Bezerra, Gardenia Carmen Gadelha Militão, Tian Li   +5 more
wiley   +1 more source

Study on the absolute configuration and biological activity of rotenoids from the leaves and twigs of Millettia pyrrhocarpa Mattapha, Forest & Hawkins, sp. Nov

BMC Complementary Medicine and Therapies, 2023
Background M. pyrrhocarpa is a new plant in the Fabaceae: Faboideae family that is found in Thailand. A literature search revealed that the Milletia genus is rich in bioactive compounds possessing a wide range of biological activities.
Suda Sananboonudom, Atchara Kaewnoi, Wilart Pompimon, Samroeng Narakaew, Suwadee Jiajaroen, Kittipong Chainok, Narong nuntasaen, Kanoknetr Suksen, Arthit Chairoungdua, Jitra Limthongkul, Chanita Naparswad, Suttiporn Pikulthong, Puttinan Meepowpan, Boonthawan Wingwon, Nichapa Charoenphakinrattana, Phansuang Udomputtimekakul   +15 more
doaj   +1 more source

Chiral Flavonoids as Antitumor Agents

Pharmaceuticals, 2021
Flavonoids are a group of natural products with a great structural diversity, widely distributed in plant kingdom. They play an important role in plant growth, development and defense against aggressors.
Cláudia Pinto, Honorina Cidade, Madalena Pinto, Maria Elizabeth Tiritan   +3 more
doaj   +1 more source

Biopesticides from Amorpha fruticosa, Can We Turn the Dice and Use This Aggressive Invasive Arboreal as Economically Prospective Source of Compounds Capable to Control Pests on Crops? [PDF]

Research Journal of Pharmacognosy
The global decline of pollinators and particularly the decline of bumblebees is a well-proven fact. Their conservation is a leading task in searching for new biopesticides. Amorpha fruticosa L. (Fabaceae) is alien invasive plant in all parts of the world.
Ekaterina Kozuharova, Abdel Rahman Al Tawaha, Giuseppe Antonio Malfa, Rosaria Aquaviva, Ardalan Pasdaran, Azadeh Hamedi*, Petranka Zdraveva, Iliana Ionkova   +7 more
doaj   +1 more source

Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue fever

Química Nova, 2012
In the search for new larvicides from plants, we have investigated the potential activity of the rotenoids deguelin (1), 12a-hydroxy-α-toxicarol (2) and tephrosin (3), isolated from the bioactive ethanol extract of roots of Tephrosia toxicaria Pers ...
Jackson Nunes e Vasconcelos, Gilvandete Maria Pinheiro Santiago, Jefferson Queiroz Lima, Jair Mafezoli, Telma Leda Gomes de Lemos, Francisca Renata Lopes da Silva, Mary Anne Sousa Lima, Antônia Torres Ávila Pimenta, Raimundo Braz-Filho, Angela Martha Campos Arriaga, Dari Cesarin-Sobrinho   +10 more
doaj   +1 more source

Synthetic Studies on Rotenoids

Agricultural and Biological Chemistry, 1968
A general cyclization reaction to dehydrorotenoids has been developed. Dehydrorotenone (III) and dehydrodeguelin (IV) were obtained in high yield from methyl derrisate (Vb) and methyl deguelate (VIb), respectively, by treatment with sodium ethoxide.
Nobuji Nakatani, Masanao Matsui
openaire   +4 more sources

A New Prenylated Flavanone from Derris trifoliata Lour.

Molecules, 2012
A new flavanone, 4′,5,7-trihydroxy-6,8-di-(2-hydroxy-3-methylbut-3-enyl)- flavanone, was isolated from the aerial parts of Derris trifoliate, together with eleven known compounds: rotenone, tephrosin, 12a-hydroxyrotenone, deguelin, 6a,12a-dehydro ...
Hao Yin, Si Zhang, Zhihui Xiao, Ximin Qiu, Cheng Jiang, Xiongming Luo, Weihong He, Shengzi Liu   +7 more
doaj   +1 more source

Aktivitas Insektisida Ekstrak Daun Dan Biji Tephrosia Vogelii J. D. Hooker (Leguminosae) Dan Ekstrak Buah Piper Cubeba L. (Piperaceae) Terhadap Larva Crocidolomia Pavonana (F.) (Lepidoptera: Crambidae) [PDF]

, 2010
Insecticidal activity of leaf and seed extracts of Tephrosia vogelii J. D. Hooker (Leguminosae) and fruit extract of Piper cubeba L. (Piperaceae) on the cabbage head caterpillar, Crocidolomia pavonana (L.) (Lepidoptera: Crambidae).
Muhamad Abizar & Djoko Prijono
core   +2 more sources

Using LC and Hierarchical Cluster Analysis as Tools to Distinguish Timbó Collections into Two Deguelia Species: A Contribution to Chemotaxonomy

Molecules, 2016
The species Deguelia utilis and Deguelia rufescens var. urucu, popularly known as “timbó,” have been used for many years as rotenone sources in insecticide formulations.
Danielle da Costa, Consuelo e Silva, Aline Pinheiro, Débora Frommenwiler, Mara Arruda, Giselle Guilhon, Cláudio Alves, Alberto Arruda, Milton Da Silva   +8 more
doaj   +1 more source

Effects of Rotenoids on Isolated Plant Mitochondria [PDF]

Plant Physiology, 1984
The effects of several rotenoids have been studied on potato (Solanum tuberosum L.) tuber and etiolated mung bean (Phaseolus aureus Roxb.) hypocotyls mitochondria. The selective inhibition of mitochondrial complex I is characterized by several tests: (a) no effect can be observed on exogenous NADH or succinate oxidation; (b) malate oxidation is ...
P, Ravanel, M, Tissut, R, Douce
openaire   +2 more sources