Results 51 to 60 of about 43,287 (200)
Frontiers in NeuroscienceIntroductionParkinson’s disease (PD) is the second most prevalent neurodegenerative disorder and is one of the leading causes of neurological disability.
Liping Sun +5 more
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, 1950 The Goodhue method is adapted to estimate rotenone in concentrations varying between 0.01 and 0.10 mg./c.c. The influence of spray auxiliaries and of dehydrorotenone, the primary decomposition product of rotenone, has been investigated.
Pollard, A. G., Subba Rao, N. V.
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Reef fish assemblages: a re-evaluation using enclosed rotenone stations [PDF]
, 2000 The reef fish assemblage at Orpheus Island, Great Barrier Reef, was examined using visual censuses and the ichthyocide rotenone. Small 3.5 m2 quantitative rotenone samples, using a fine-mesh net to enclose the site, were compared with visual-point ...
Ackerman, John L., Bellwood, David R.
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Role of PARP-1 in mitochondroal DNA damage induced by rotenone in PC12 cells
Di-san junyi daxue xuebao, 2019 Objective To explore the effect of poly (ADP-ribose) polymerase-1 (PARP-1) on mitochondrial DNA (mtDNA) damage induced by rotenone in rat adrenal medulla pheochromocytoma PC12 cells. Methods PC12 cells were treated with various dose of rotenone.
XIAO Jingsong, HOU Guizhong, SAI Yan
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Cell cycle regulation of DNA polymerase beta in rotenone-based Parkinson's disease models. [PDF]
PLoS ONE, 2014 In Parkinson's disease (PD), neuronal cells undergo mitotic catastrophe and endoreduplication prior to cell death; however, the regulatory mechanisms remain to be defined.
Hongcai Wang +7 more
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Mechanism of Toxicity in Rotenone Models of Parkinson's Disease
, 2003 Exposure of rats to the pesticide and complex I inhibitor rotenone reproduces features of Parkinson's disease, including selective nigrostriatal dopaminergic degeneration and α-synuclein-positive cytoplasmic inclusions (Betarbet et al., 2000; Sherer et ...
J. Timothy Greenamyre +9 more
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Animal Cells and Systems, 2018 Leucine-rich repeat kinase 2 (LRRK2) is involved in Parkinson’s disease (PD) pathology. A previous study showed that rotenone treatment induced apoptosis, mitochondrial damage, and nucleolar disruption via up-regulated LRRK2 kinase activity, and these ...
Jihoon Jang +9 more
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Synthesis and bioactivity of rotenone oxime O-ether derivatives
, 2012 A series of rotenone oxime O-ether derivatives were synthesized and characterized. All compounds were tested for their insecticidal, miticidal and fungicidal activities against the selected pests and compared with those of rotenone.
Wang, Y, Zhou, Z, Cao, G
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Pramipexole protective effect on rotenone induced neurotoxicity in mice
, 2011 Introduction: Pramipexole is a new dopaminergic drug which has been approved for PD treatment. However, we tried to find a new capacity for this drug rather than symptomatic effect. Materials and Methods: A chronic
Mohamed M. Salama +6 more
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Effects of chronic low dose rotenone treatment on human microglial cells
Molecular Neurodegeneration, 2009 Background Exposure to toxins/chemicals is considered to be a significant risk factor in the pathogenesis of Parkinson's disease (PD); one putative chemical is the naturally occurring herbicide rotenone that is now used widely in establishing PD models ...
Nicholson Louise FB, Shaikh Shamim B
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