Results 41 to 50 of about 48,544 (194)
Low doses of rotenone upon mitohormesis [PDF]
, 2013 The mitochondrial toxin rotenone exerts cytotoxicity via overproduction of reactive oxygen species (ROS) and depolarization of the mitochondrial membrane.
Yuyun, Xiong +7 more
core +3 more sources
Pyrroloquinoline Quinone Inhibits Rotenone-Induced Microglia Inflammation by Enhancing Autophagy
, 2020 Neuroinflammation is a feature common to neurodegenerative diseases, such as Parkinson’s disease (PD), which might be responsive to therapeutic intervention. Rotenone has been widely used to establish PD models by inducing mitochondrial dysfunction
Fei Ding +6 more
core +1 more source
Role of PARP-1 in mitochondroal DNA damage induced by rotenone in PC12 cells
Di-san junyi daxue xuebao, 2019 Objective To explore the effect of poly (ADP-ribose) polymerase-1 (PARP-1) on mitochondrial DNA (mtDNA) damage induced by rotenone in rat adrenal medulla pheochromocytoma PC12 cells. Methods PC12 cells were treated with various dose of rotenone.
XIAO Jingsong, HOU Guizhong, SAI Yan
doaj +1 more source
Neuroprotection in a rotenone model of Parkinson's disease [PDF]
, 2015 The pesticide/neurotoxin, rotenone, has been shown to cause systemic inhibition of mitochondrial complex I activity, with consequent degeneration of the nigrostriatal pathway, as observed in Parkinson’s disease.
Carriere, Candace
core +1 more source
Effects of Low Concentrations of Rotenone Upon Mitohormesis in SH-SY5Y Cells
Dose-Response, 2013 The mitochondrial toxin rotenone exerts cytotoxicity via overproduction of reactive oxygen species (ROS) and depolarization of the mitochondrial membrane.
Xiong Yuyun +7 more
doaj +1 more source
Effect of ALF186 on rotenone-induced apoptosis.
, 2013 A: Representative experiment after FITC Annexin V and propidiumiodide staining and flow-cytometric analysis. 1×104 cells in each experiment were analyzed.
Julia Biermann (131071) +7 more
core +1 more source
PHOTOOXYGENATION OF ROTENONE [PDF]
Chemistry Letters, 1974 Abstract In the photooxygenation of rotenone(I) in pyridine solution, two isomers of rotenolones, 6aβ, 12aβ- and 6aβ, 12aα-rotenolones (II and III), were obtained besides dehydrorotenone(V) and rotenonone(VI). As one of acidic products, a keto-acid (IVa) was also isolated.
Mitsuo Chubachi, Masayuki Hamada
openaire +1 more source
Redox ReportBackground Pulmonary metastases in osteosarcoma (OS) are associated with a poor prognosis. Rotenone has shown anti-cancer activity. However, its effects on metastasis and the underlying mechanisms remain unknown. This study investigated the potential use
Xiang Ma +10 more
doaj +1 more source
Cells, 2018 Current treatments for Parkinson’s disease (PD) only alleviate symptoms doing little to inhibit the onset and progression of the disease, thus we must research the mechanism of Parkinson’s.
Ethan Chernivec +2 more
doaj +1 more source
Effect of rotenone-induced stress on physiologically active substances in adult Aphis glycines.
PLoS ONE, 2020 The aim of this study was to determine the effect of rotenone stress on Aphis glycines Matsumura (Hemiptera: Aphididae) populations in different habitats of Northeast China.
Lanlan Han +9 more
doaj +1 more source