Results 21 to 30 of about 43,287 (200)

Unexpected improvements of spatial learning and memory abilities in chronic rotenone intoxicated mice. [PDF]

PLoS ONE, 2014
The liposoluble insecticide rotenone is commonly used as a mitochondrial complex I inhibitor to replicate Parkinson's disease (PD) pathological features.
Fengju Jia, Ning Song, Chenyang Zhao, Junxia Xie, Hong Jiang   +4 more
doaj   +1 more source

pklemmer/Generating heatmaps from expression data

, 2022
This repository contains an R script for (GEO2R rotenone) dataset heatmap plot generation in addition to GEO 2 R rotenone exposure expression datasets (tsv) as well as the corresponding heatmap plot (svg)
Pierre Klemmer
core   +1 more source

An Assessment of the Effect of Rotenone on Selected Non-Target Aquatic Fauna. [PDF]

PLoS ONE, 2015
Rotenone, a naturally occurring ketone, is widely employed for the management of invasive fish species. The use of rotenone poses serious challenges to conservation practitioners due to its impacts on non-target organisms including amphibians and ...
Tatenda Dalu, Ryan J Wasserman, Martine Jordaan, William P Froneman, Olaf L F Weyl   +4 more
doaj   +1 more source

Modulation of dopamine metabolizing enzymes and antioxidant status by Capsicum annuum Lin in rotenone-intoxicated rat brain

Toxicology Reports, 2019
Rotenone is a natural pesticide and environmental neurotoxin which mimics key aspects of Parkinson’s disease. This study evaluated the effect of ethyl acetate extract of Capsicum annuum L. (C. annuum) in rotenone-intoxicated rats. Oral doses of C. annuum
Omodesola Oluwafisayo Ogunruku, Bolanle Olanrewaju Ogunyemi, Ganiyu Oboh, Oluwaseun Oyeniyi Babatunde, Aline Augusti Boligon   +4 more
doaj   +1 more source

Low Concentration of Rotenone Impairs Membrane Function of Spodoptera litura Cells by Promoting Their Aggregation

Agronomy, 2022
Rotenone is a widely used botanical insecticide, which can inhibit the mitochondrial respiratory chain of various insect cells, while the mechanism of its toxicity to insect cells needs further investigation.
Sukun Lin, Kaijie Xu, Qingpeng Zhang, Qiuming Zhu, Muhammad Musa Khan, Zhixiang Zhang, Dongmei Cheng   +6 more
doaj   +1 more source

Microglial activation contributes to cognitive impairments in rotenone-induced mouse Parkinson’s disease model

Journal of Neuroinflammation, 2021
Background Cognitive decline occurs frequently in Parkinson’s disease (PD), which greatly decreases the quality of life of patients. However, the mechanisms remain to be investigated.
Dongdong Zhang, Sheng Li, Liyan Hou, Lu Jing, Zhengzheng Ruan, Bingjie Peng, Xiaomeng Zhang, Jau-Shyong Hong, Jie Zhao, Qingshan Wang   +9 more
doaj   +1 more source

The neuroprotective effect of human uncoupling protein 2 (hUCP2) requires cAMP-dependent protein kinase in a toxin model of Parkinson's disease

Neurobiology of Disease, 2014
Parkinson's disease (PD), caused by selective loss of dopaminergic (DA) neurons in the substantia nigra, is the most common movement disorder with no cure or effective treatment.
Ran-Der Hwang, Lyle Wiemerslage, Christopher J. LaBreck, Munzareen Khan, Kavitha Kannan, Xinglong Wang, Xiongwei Zhu, Daewoo Lee, Yih-Woei C. Fridell   +8 more
doaj   +1 more source

Rotenone-induced mitochondrial complex I inhibition promotes lipid peroxidation in BeWo trophoblast cells.

, 2020
Panel A: Five major protein bands with molecular weights of approximately 90, 70, 50, 45, and 35 kDa showed immunoreactivity for 4-HNE modifications in control and treated trophoblast cells from whole cell lysates.
O’Llenecia S. Walker (8486163), Michael K. Wong (646399), Mohamed Adam (529112), Sandeep Raha (177509), Rehginald Ragos (8486166), Anson Cheung (8486169)   +5 more
core   +1 more source

Neuroprotective effect of butin against rotenone-induced Parkinson’s disease mediated by antioxidant and anti-inflammatory actions through paraoxonase-1-induction

Journal of Taibah University for Science, 2022
This investigation aimed to assess the anti-Parkinson's effect of butin in rotenone-treated rats. A total of 24 albino Wistar rats were segregated into four groups equally as follows: Group I (normal) and Group II (rotenone control); Group III and Group ...
Fahad A. Al-Abbasi
doaj   +1 more source

The eradication of invasive species using rotenone and its impact on freshwater macroinvertebrates [PDF]

, 2022
Norsk sammendrag Hvordan påvirkes bunndyr når fremmede arter utryddes med rotenon? Fremmede arter er arter som tilsiktet eller utilsiktet spres av mennesker til nye områder der de ikke naturlig hører hjemme.
Kjærstad, Gaute
core