Reversal effect of Solanum dasyphyllum against rotenone-induced neurotoxicity [PDF]
Current Issues in Pharmacy and Medical Sciences, 2020 We earlier reported the protective effect of Solanum dasyphyllum against cyanide neurotoxicity. In furtherance to this, we investigated the protective effect of S.
Ilesanmi Omotayo B. +6 more
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Neuroprotective effects of paederoside against mitochondrial dysfunction in rotenone-induced cell models of Parkinson’s disease [PDF]
Frontiers in NeuroscienceIntroductionParkinson’s disease (PD) is the second most prevalent neurodegenerative disorder and is one of the leading causes of neurological disability.
Liping Sun +5 more
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Ginseng extract G115 improves locomotor function in rotenone-induced parkinsonism rats via an antioxidant effect [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2015 Exposure to certain pesticides including rotenone, a mitochondrial complex I inhibitors, may cause the oxidative damage to the dopaminergic neurons and contribute to Parkinson’s disease.
Pailin Euaruksakul +2 more
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Toxicology Reports, 2019 Rotenone is a natural pesticide and environmental neurotoxin which mimics key aspects of Parkinson’s disease. This study evaluated the effect of ethyl acetate extract of Capsicum annuum L. (C. annuum) in rotenone-intoxicated rats. Oral doses of C. annuum
Omodesola Oluwafisayo Ogunruku +4 more
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Acute rotenone poisoning: A scoping review [PDF]
HeliyonContext: Rotenone is a toxic chemical found in various plants, including some used as food. Rotenone poisoning can be fatal and there is no antidote.
John Tat, Karen Heskett, Gerry R. Boss
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Rotenone targets midbrain astrocytes to produce glial dysfunction-mediated dopaminergic neurodegeneration [PDF]
Acta Neuropathologica CommunicationsExposure to pesticides, such as rotenone or paraquat, is an environmental factor that plays an important role in the pathogenesis of Parkinson's disease (PD). Rotenone induces PD-like pathology and is therefore used to develop parkinsonian animal models.
Ikuko Miyazaki +10 more
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Antioxidant and Neuroprotective Activity of Wheat Microgreen Extracts against Rotenone Induced Neurotoxicity in Caenorhabditis elegans [PDF]
Journal of Clinical and Biomedical SciencesBackground: Wheatgrass (Triticum, Family: Poaceae) juice is considered as a living food and often consumed due to its countless health benefits. Wheatgrass juice contains many bioactive compounds which can be useful for ameliorating neurogenerative ...
Sonane Madhavi, Saxena Sangeeta
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Cerebrolysin protects against rotenone-induced oxidative stress and neurodegeneration
Journal of Neurorestoratology, 2014 Omar ME Abdel-Salam,1 Nadia A Mohammed,2 Eman R Youness,2 Yasser A Khadrawy,3 Enayat A Omara,4 Amany A Sleem51Department of Toxicology and Narcotics, 2Department of Medical Biochemistry, 3Department of Physiology, 4Department of Pathology, 5Department of
Abdel-Salam OME +5 more
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Cell cycle regulation of DNA polymerase beta in rotenone-based Parkinson's disease models. [PDF]
PLoS ONE, 2014 In Parkinson's disease (PD), neuronal cells undergo mitotic catastrophe and endoreduplication prior to cell death; however, the regulatory mechanisms remain to be defined.
Hongcai Wang +7 more
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Rotenone-Induced Optic Nerve Damage and Retinal Ganglion Cell Loss in Rats
BiomoleculesRotenone is a mitochondrial complex I inhibitor that causes retinal degeneration. A study of a rat model of rotenone-induced retinal degeneration suggested that this model is caused by indirect postsynaptic N-methyl-D-aspartate (NMDA) stimulation ...
Yasuko Yamamoto +2 more
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