Results 11 to 20 of about 43,287 (200)

Reversal effect of Solanum dasyphyllum against rotenone-induced neurotoxicity

Current Issues in Pharmacy and Medical Sciences, 2020
We earlier reported the protective effect of Solanum dasyphyllum against cyanide neurotoxicity. In furtherance to this, we investigated the protective effect of S.
Ilesanmi Omotayo B., Efe Obade, Odewale Temitope T., Atanu Francis O., Adeogun Esther F., Akinmoladun Afolabi C., Olaleye Tolulope M.   +6 more
doaj   +3 more sources

Rotenone Neurotoxicity Causes Dopamine Neuron Loss in Zebrafish

University of Ottawa Journal of Medicine, 2015
: Objectives: We sought to determine whether rotenone, a commonly used pesticide, exhibits neurotoxicity in zebrafish by causing dopamine neuron loss through rotenone-induced oxidative damage.
Simon Martel, Jonathan Y Keow, Marc Ekker   +2 more
doaj   +3 more sources

Pyrrolidine dithiocarbamate ameliorates rotenone-induced Parkinson’s disease in rats

Bulletin of Faculty of Pharmacy Cairo University, 2017
Pyrrolidine dithiocarbamate (PDTC), a low-molecular-weight thiol antioxidant, possesses neuroprotection; however, its possible modulatory effect in Parkinson’s disease (PD) has not been tested.
Noha F. Abdelkader, Nadia M. Arafa, Amina S. Attia, Afaf A. Ain-Shoka, Dalaal M. Abdallah   +4 more
doaj   +2 more sources

Acute rotenone poisoning: A scoping review [PDF]

Heliyon
Context: Rotenone is a toxic chemical found in various plants, including some used as food. Rotenone poisoning can be fatal and there is no antidote.
John Tat, Karen Heskett, Gerry R. Boss
doaj   +2 more sources

Antioxidant and Neuroprotective Activity of Wheat Microgreen Extracts against Rotenone Induced Neurotoxicity in Caenorhabditis elegans [PDF]

Journal of Clinical and Biomedical Sciences
Background: Wheatgrass (Triticum, Family: Poaceae) juice is considered as a living food and often consumed due to its countless health benefits. Wheatgrass juice contains many bioactive compounds which can be useful for ameliorating neurogenerative ...
Sonane Madhavi, Saxena Sangeeta
doaj   +2 more sources

Cerebrolysin protects against rotenone-induced oxidative stress and neurodegeneration

Journal of Neurorestoratology, 2014
Omar ME Abdel-Salam,1 Nadia A Mohammed,2 Eman R Youness,2 Yasser A Khadrawy,3 Enayat A Omara,4 Amany A Sleem51Department of Toxicology and Narcotics, 2Department of Medical Biochemistry, 3Department of Physiology, 4Department of Pathology, 5Department of
Abdel-Salam OME, Mohammed NA, Youness ER, Khadrawy YA, Omara EA, Sleem AA   +5 more
doaj   +1 more source

Deferoxamine and Curcumin Loaded Nanocarriers Protect Against Rotenone-Induced Neurotoxicity [PDF]

, 2020
Background: Reduced glutathione and excess free iron within dopaminergic, substantia nigra neurons in Parkinson's disease (PD) can drive accumulation of toxic hydroxyl radicals resulting in sustained oxidative stress and cellular damage.
Zariwala, M., Mursaleen, L., Somavarapu, S.   +2 more
core   +1 more source

Rotenone-Induced Neurodegeneration Is Enabled by a p38-Parkin-ROS Signaling Feedback Loop

, 2021
Rotenone, a component of pesticides, is widely used in agriculture and potentially causes Parkinson’s disease (PD). However, the regulatory mechanisms of rotenone-induced PD are unclear.
Mingque Li (11705062), He Zhang, Xueqiong Zhou (11705065), Jialong Chen (1937167), Ailun Xie (11705068), Linhua Liu, He Zhang (130319), Mingque Li, Ailun Xie, Linhua Liu (8925602), Ziwei Cai (11705071), Chunlai Fu (11705074), Yongming Peng (11705077), Chunlai Fu, Ziwei Cai, Yongming Peng, Xueqiong Zhou, Jialong Chen   +17 more
core   +1 more source

Glial cells modulate retinal cell survival in rotenone-induced neural degeneration

Scientific Reports, 2021
Administration of the mitochondrial complex I inhibitor rotenone provides an excellent model to study the pathomechanism of oxidative stress-related neural degeneration diseases.
Hiroshi Tawarayama, Maki Inoue-Yanagimachi, Noriko Himori, Toru Nakazawa   +3 more
doaj   +1 more source

pklemmer/Generating volcano plots from expression data

, 2022
This repository contains an R script for (GEO2R rotenone) dataset volcano plot generation in addition to GEO 2 R rotenone exposure expression datasets (tsv) as well as the corresponding volcano plots (svg)
Pierre Klemmer
core   +1 more source