Results 81 to 90 of about 67,204 (291)
The greening of analytical methods has gained increasing interest in the field of pharmaceutical analysis to reduce environmental impacts and improve the health safety of analysts.
Moussa Yabré+3 more
doaj +1 more source
Abstract The synthesis of docosahexaenoic acid (DHA)‐enriched medium‐ and long‐chain triacylglycerols (MLCT), particularly with DHA at the sn‐2 position and medium chain fatty acids (MCFA) at the sn‐1,3 positions, is a promising strategy to enhance DHA bioavailability.
Evelyn Ling Lee+8 more
wiley +1 more source
Ferrocene derivatives with planar chirality and their enantioseparation by liquid‐phase techniques
Abstract In the last decade, planar chiral ferrocenes have attracted a growing interest in several fields, particularly in asymmetric catalysis, medicinal chemistry, chiroptical spectroscopy and electrochemistry. In this frame, the access to pure or enriched enantiomers of planar chiral ferrocenes has become essential, relying on the availability of ...
Paola Peluso, Victor Mamane
wiley +1 more source
The lichens Sticta tomentosa and Sticta damaecornis were extracted to obtain glycoproteins. The extracts were fractionated with 30-80% saturation (NH4)2SO4. The fractions were reduced, alkylated and after dialysis the material were digested with trypsin.
Patrícia Fidelis de Oliveira+4 more
doaj +1 more source
Abstract We present the first use of a bioengineered mammalian transposase system derived from Myotis lucifugus (bMLT) for integration of expression vectors into the CHO genome, focusing on GFP and trastuzumab production. Initially, CHO‐K1 cells are transfected with a GFP reporter and varying amounts of bMLT DNA or mRNA.
Nicolas Marx+10 more
wiley +1 more source
Enantioselective CE–MS analysis of ketamine metabolites in urine
Abstract The chiral drug ketamine has long‐lasting antidepressant effects with a fast onset and is also suitable to treat patients with therapy‐resistant depression. The metabolite hydroxynorketamine (HNK) plays an important role in the antidepressant mechanism of action.
Friederike A. Sandbaumhüter+5 more
wiley +1 more source
ABSTRACT Chemical investigation of Disynaphia filifolia (Hassl.) R.M. King & H. Rob. (Asteraceae) led to the isolation of eight compounds, with tremetone being the major metabolite recovered. Tremetone has been suggested as the toxic compound in Ageratina altissima and Isocoma pluriflora, two species of the Asteraceae family. Although D.
Yasmin Rodrigues Chierici+11 more
wiley +1 more source
ABSTRACT In recent years, much research has focused on the valorization of Crocus sativus by‐products as sources of bioactive compounds. This study was designed to investigate the impact of two different drying methods, freeze‐drying and air‐drying, on the phenolic content and antioxidant activity of leaves and tepals by‐products from C.
Soukaina Abou‐Wakil+9 more
wiley +1 more source
We examined D‐amino acids in diabetic kidney disease (DKD). Among D‐amino acids, blood D‐serine was identified as a biomarker of DKD, and we found that short‐term change in blood D‐serine showed higher value in fast decliners in DKD patients, which meant the prognostic value of blood D‐serine in DKD.
Yosuke Hirakawa+7 more
wiley +1 more source
Assessing the growth kinetics and stoichiometry of Escherichia coli at the single‐cell level
Abstract Microfluidic cultivation and single‐cell analysis are inherent parts of modern microbial biotechnology and microbiology. However, implementing biochemical engineering principles based on the kinetics and stoichiometry of growth in microscopic spaces remained unattained.
Katharina Smaluch+5 more
wiley +1 more source