Results 111 to 120 of about 28,118 (222)

RpoB subfamilies.

, 2013
A Lek clustering method was applied to all RpoB superfamily members retrieved from the NRAA database, microbial genome projects, and the GOS data set. Clusters that contain only sequences from the GOS data set are noted as “From GOS only.”*Clusters 1, 9,
Jonathan A. Eisen (93505), Aaron Halpern (1482), Martin Wu (2823), Shibu Yooseph (38227), Dongying Wu (9076), J. Craig Venter (38236), Douglas B. Rusch (38226), Marvin Frazier (38235)   +7 more
core   +1 more source

Proportion of rpoB-S531L and other mutations in rpoB acquired by INH-resistant M. tuberculosis strains compared to their susceptible parent strains.

, 2013
Results for all INH-resistant strains are grouped, as well as the results for are wildtype strains. Mutation distribution obtained for the INH-resistant group and the wildtype group and rpoB mutation distribution obtained for the two different ...
Anja Schuitema (141408), Kristin Kremer (62793), Paul Klatser (141432), Richard Anthony (141435), Brian Kwok (336135), Dick van Soolingen (62818), Indra Bergval (141381)   +6 more
core   +1 more source

Phylogenetic tree of the RpoB superfamily.

, 2013
All RpoB sequences were grouped into clusters using the Lek algorithm. Representatives of each cluster that contained >2 members were then selected and aligned using MUSCLE.
Jonathan A. Eisen (93505), Aaron Halpern (1482), Martin Wu (2823), Shibu Yooseph (38227), Dongying Wu (9076), J. Craig Venter (38236), Douglas B. Rusch (38226), Marvin Frazier (38235)   +7 more
core   +1 more source

Mechanisms of fitness cost reduction for rifampicin-resistant strains with deletion or duplication mutations in rpoB.

, 2018
Rifampicin resistance (Rif(R)) is caused by mutations in rpoB, encoding the beta-subunit of RNA polymerase. Rif(R )mutations generally incur a fitness cost and in resistant isolates are frequently accompanied by compensatory mutations in rpoA, rpoB or ...
Brandis, Gerrit,, Brandis, Gerrit, Hughes, Diarmaid, Hughes, Diarmaid,   +3 more
core   +1 more source

Identification of echinoderm metabolites as potential inhibitors targeting wild-type and mutant forms of Escherichia coli RNA polymerase (RpoB) for tuberculosis treatment.

PLoS ONE
Tuberculosis (TB) remains a critical global health challenge, with the emergence of drug-resistant strains heightening concerns. The development of effective drugs targeting both wild-type (WT) and mutant Escherichia coli RNA polymerase β subunit (RpoB ...
Fatimah M Alsulais, Bayan A Alhaidhal, Ramzi A Mothana, Abdullah R Alanzi   +3 more
doaj   +1 more source

Level of rpoB partial sequence similarity among six species of oral Veillonella.

, 2016
Level of rpoB partial sequence similarity among six species of oral Veillonella.
Izumi Mashima (3165120), Futoshi Nakazawa (3165111), Boonyanit Thaweboon (3165114), Sroisiri Thaweboon (3165108), Citra Fragrantia Theodorea (3165117)   +4 more
core   +1 more source

Molecular characterization of rifabutin-resistance in refractory Helicobacter pylori infection in Taiwan

International Journal of Infectious Diseases
Objectives: To explore the molecular characteristics of rpoB, encoding β-subunit of DNA-directed RNA polymerase, and unravel the link to rifabutin-resistance in patients with refractory Helicobacter pylori infection. Methods: From January 2018-March 2021,
Chia-Jung Kuo, Ngoc-Niem Bui, Jun-Nong Ke, Cheng-Yu Lin, Wey-Ran Lin, Ming-Ling Chang, Hui-Yu Wu, Mei-Zi Huang, Cheng-Hsun Chiu, Cheng-Tang Chiu, Chih-Ho Lai   +10 more
doaj   +1 more source

Global prevalence of Mycobacterium massiliense strains with recombinant rpoB genes (Rec-Mas) horizontally transferred from Mycobacterium abscessus: two major types, dominant circulating clone 7 and MLST ST46 sequence type

Microbiology Spectrum
Mycobacterium abscessus is a group of emerging antimicrobial-resistant nontuberculous mycobacteria that causes severe lung disease in infected patients globally.
Dong Hyun Kim, Hyejun Seo, Sangkwon Jung, Bum-Joon Kim   +3 more
doaj   +1 more source

Expression of cloned rpoB gene of Escherichia coli: a genetic system for the isolation of dominant negative mutations and overproduction of defective beta subunit of RNA polymerase.

The rifampin resistance rifD18 allele of rpoB, carried on the expression plasmid pXT7 beta, is controlled by a strong bacteriophage T7 late promoter and two weak Escherichia coli promoters.
Lee, J Y, McKinney, J D, Park, J H, Goldfarb, A, Zalenskaya, K, Shin, Y K   +5 more
core   +1 more source

Non-synonymous mutations detected on the rpoB gene among retreatment cases.

, 2019
Non-synonymous mutations detected on the rpoB gene among retreatment cases.
Julia Feldmann (149820), Jerry Hella (801219), Klaus Reither (259897), Aladino Jaleco (6585539), Raymond Shirima (6585551), Sebastien Gagneux (149824), Miriam Reinhard (6181745), Basra Doulla (801220), Daniela Brites (192428), Ally Kingazi (6585542), Lujeko Kamwela (3727402), Anna Doetsch (6585554), Sonia Borrell (149821), Mohamed Sasamalo (801223), Amri Kingalu (6585545), Bryceson Malewo (6585548), Lukas Fenner (149822), Liliana K. Rutaihwa (6585536)   +17 more
core   +1 more source