Consilium Medicum, 2022 The PPARG gene has the great value in predicting of carbohydrate metabolism disorders development and the patients response to different therapy options.
Kamilya B. Khasanova +5 more
doaj +2 more sources
Ожирение и метаболизм, 2020 BACKGROUND: The polymorphism rs1801282 (Pro12Ala) may be one of the reasons for the heterogeneous response of patients with carbohydrate metabolism disorders to thiazolidinedione therapy.
Tatyana V. Eremenko +4 more
doaj +3 more sources
Prevalence of the rs1801282 single nucleotide polymorphism of the PPARG gene in patients with metabolic syndrome [PDF]
Archives of Endocrinology and Metabolism, 2015 Objective This study aimed to get the genotypic and allelic frequencies of rs1801282 in 179 volunteer donors and 154 patients with Metabolic syndrome (MetS) in Brasilia, Brazil and also examine the association with anthropometric, biochemical and ...
Renato Marano Rocha +5 more
doaj +5 more sources
Genetic Predisposition to Prediabetes in the Kazakh Population [PDF]
Current Issues in Molecular BiologyThe aim of this study was to conduct a comparative analysis of the population frequencies of the minor allele of polymorphic variants in the genes TCF7L2 (rs7903146) and PPARG (rs1801282), based on the genome-wide association studies analysis data ...
Gulnara Svyatova +6 more
doaj +2 more sources
Association between PPARγ, PPARGC1A, and PPARGC1B genetic variants and susceptibility of gastric cancer in an Eastern Chinese population [PDF]
BMC Medical Genomics, 2022 Purpose Previous studies showed that peroxisome proliferator-activated receptor gamma (PPARγ) and PPARγ coactivator1 family (PPARGC1A and PPARGC1B) gene single nucleotide variants (SNVs)were strongly associated with cancer susceptibility.
Boyang Chen +6 more
doaj +2 more sources
Медицинский вестник Юга России, 2021 Objective: To study the effect of the rs1801282 PPARG polymorphism on changes in the body composition of patients with early carbohydrate metabolism disorders in groups with different variants of treatment.Materials and Methods: The study involved 64 ...
F. V. Valeeva +4 more
doaj +3 more sources
Journal of Education, Health and Sport, 2016 Ziablytsev S. V., Mokrii V. Y., Crystal M. V. The value of polymorphism RRO12ALA gene PPARG in violation of lipid peroxidation and antioxidant protection in patients with type 2 diabetes mellitus. Journal of Education, Health and Sport. 2016;6(9):626-636.
S. V. Ziablytsev +2 more
doaj +9 more sources
Polymorphisms of the PPAR-γ (rs1801282) and Its Coactivator (rs8192673) Have a Minor Effect on Markers of Carotid Atherosclerosis in Patients with Type 2 Diabetes Mellitus [PDF]
PPAR Research, 2016 Background. The present study was designed to clarify whether common single nucleotide polymorphisms (SNPs) of the Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) gene (rs1801282) and the Peroxisome Proliferator-Activated Receptor-γ Coactivator-1 ...
Aleš Pleskovič +4 more
doaj +3 more sources
Polymorphisms FTO rs9939609, PPARG rs1801282 and ADIPOQ rs4632532 and rs182052 but not lifestyle are associated with obesity related-traits in Mexican children [PDF]
Genetics and Molecular Biology, 2016 Concerning the genetic factors of obesity, no consistent association between populations has been reported, which may be due to the frequency of polymorphisms, the lifestyle of studied populations and its interaction with other factors.
C Muñoz-Yáñez +6 more
doaj +6 more sources
The Analysis of ECE1 and PPARG Variants in the Development of Osteopenia and Osteoporosis in Postmenopausal Women [PDF]
BiomedicinesOsteoporosis is a multifactorial systemic skeletal disease that is characterized by a low bone mineral density (BMD) and the microarchitectural deterioration of bone tissue, leading to bone fragility.
Izabela Uzar +8 more
doaj +2 more sources