Ожирение и метаболизм, 2020 BACKGROUND: The polymorphism rs1801282 (Pro12Ala) may be one of the reasons for the heterogeneous response of patients with carbohydrate metabolism disorders to thiazolidinedione therapy.
Tatyana V. Eremenko +4 more
doaj +3 more sources
Consilium Medicum, 2022 The PPARG gene has the great value in predicting of carbohydrate metabolism disorders development and the patients response to different therapy options.
Kamilya B. Khasanova +5 more
doaj +2 more sources
Relationship between PPAR‐γ gene polymorphisms and ischemic stroke risk: A meta‐analysis
Brain and Behavior, 2021 Background Published researches have suggested some associations between PPAR‐γ and ischemic stroke (IS) development. This meta‐analysis was conducted to evaluate the association between PPAR‐γ gene polymorphisms and IS risk.
Fan Cheng +3 more
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Prevalence of the rs1801282 single nucleotide polymorphism of the PPARG gene in patients with metabolic syndrome [PDF]
Archives of Endocrinology and Metabolism, 2015 Objective This study aimed to get the genotypic and allelic frequencies of rs1801282 in 179 volunteer donors and 154 patients with Metabolic syndrome (MetS) in Brasilia, Brazil and also examine the association with anthropometric, biochemical and ...
Renato Marano Rocha +5 more
doaj +5 more sources
Медицинский вестник Юга России, 2021 Objective: To study the effect of the rs1801282 PPARG polymorphism on changes in the body composition of patients with early carbohydrate metabolism disorders in groups with different variants of treatment.Materials and Methods: The study involved 64 ...
F. V. Valeeva +4 more
doaj +3 more sources
Journal of Education, Health and Sport, 2016 Ziablytsev S. V., Mokrii V. Y., Crystal M. V. The value of polymorphism RRO12ALA gene PPARG in violation of lipid peroxidation and antioxidant protection in patients with type 2 diabetes mellitus. Journal of Education, Health and Sport. 2016;6(9):626-636.
S. V. Ziablytsev +2 more
doaj +9 more sources
Polymorphisms of the PPAR-γ (rs1801282) and Its Coactivator (rs8192673) Have a Minor Effect on Markers of Carotid Atherosclerosis in Patients with Type 2 Diabetes Mellitus [PDF]
PPAR Research, 2016 Background. The present study was designed to clarify whether common single nucleotide polymorphisms (SNPs) of the Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) gene (rs1801282) and the Peroxisome Proliferator-Activated Receptor-γ Coactivator-1 ...
Aleš Pleskovič +4 more
doaj +3 more sources
Polymorphisms FTO rs9939609, PPARG rs1801282 and ADIPOQ rs4632532 and rs182052 but not lifestyle are associated with obesity related-traits in Mexican children [PDF]
Genetics and Molecular Biology, 2016 Concerning the genetic factors of obesity, no consistent association between populations has been reported, which may be due to the frequency of polymorphisms, the lifestyle of studied populations and its interaction with other factors.
C Muñoz-Yáñez +6 more
doaj +6 more sources
Genetic markers of cardiac autonomic neuropathy in the Kazakh population [PDF]
BMC Cardiovascular DisordersBackground Cardiac autonomic neuropathy (CAN) is a complication of diabetes mellitus (DM) that increases the risk of morbidity and mortality by disrupting cardiac innervation.
Nazira Bekenova +5 more
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The Effect of PPARγ rs1801282 Variant on Mortality Risk Among Asians With Chronic Kidney Disease: A Cohort Study and Meta-Analysis [PDF]
Frontiers in Genetics, 2022 Background: Chronic kidney disease (CKD) is a public health issue, and an independent risk factor for cardiovascular disease. The peroxisome proliferator-activated receptor gamma (PPARG) plays an important role in the cardiovascular system.
Wei-Teing Chen +14 more
doaj +3 more sources