Results 31 to 40 of about 1,303 (153)

The single nucleotide polymorphism rs11643718 in SLC12A3 is associated with the development of diabetic kidney disease in Chinese people with type 2 diabetes

Diabetic Medicine, Volume 37, Issue 11, Page 1879-1889, November 2020., 2020
Abstract Aims To examine the association between 24 literature‐based single nucleotide polymorphisms and diabetic kidney disease in Chinese people with type 2 diabetes. Methods and results Twenty‐four candidate diabetic kidney disease‐susceptible single nucleotide polymorphisms were genotyped in 208 participants with type 2 diabetes and diabetic kidney
J.‐F. Yang, X.‐F. Xiong, Y. Xiao, L. Wei, L. Li, M. Yang, Y.‐C. Han, H. Zhao, C.‐R. Li, N. Jiang, S. Xiong, L.‐F. Zeng, Z.‐G. Zhou, S.‐P. Liu, N.‐S. Wang, Y. Fan, L. Sun   +16 more
wiley   +1 more source

Association study of rs1801282 PPARG gene polymorphism and immune cells and cytokine levels in a Spanish pregnant women cohort and their offspring [PDF]

Journal of Biomedical Science, 2020
AbstractBackgroundPeroxisome proliferator activated receptor gamma (PPARG) belongs to the nuclear receptor superfamily functioning as transcription factors to regulate cellular differentiation, development and metabolism. Moreover, it has been implicated in the regulation of lipid metabolism, as well as the maturation of monocytes/macrophages and the ...
Maria García-Ricobaraza, Mercedes García-Bermúdez, Francisco J. Torres-Espinola, M. Teresa Segura Moreno, Mathieu N. Bleyere, Ligia E. Díaz-Prieto, Esther Nova, Ascensión Marcos, Cristina Campoy   +8 more
openaire   +6 more sources

Ethnic differences in adiposity and diabetes risk – insights from genetic studies

Journal of Internal Medicine, Volume 288, Issue 3, Page 271-283, September 2020., 2020
Content List ‐ Read more articles from the symposium: “Obesity and Type 2 Diabetes: Understanding the Role of Ethnicity”. Abstract Type 2 diabetes is more common in non‐Europeans and starts at a younger age and at lower BMI cut‐offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of ...
H. Yaghootkar, B. Whitcher, J. D. Bell, E. L. Thomas   +3 more
wiley   +1 more source

Ассоциации молекулярно-генетических предикторов сахарного диабета 2-го типа с гипергликемией у новорожденных с экстремально низкой массой тела [PDF]

, 2021
Hyperglycemia in premature newborns is an independent risk factor for death, so blood glucose testing is widely used in the practice of neonatal intensive care units.Objective: to evaluate the associations of the frequency of carriage of allelic variants
А. U. Lekmanov, Р. Р. Валиев, R. R. Valiev, Н. Н. Мингазов, А. У. Лекманов, N. N. Mingazov, P. I. Mironov, П. И. Миронов   +7 more
core   +1 more source

UEG Week 2023 Moderated Posters

, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 201-534, October 2023.
wiley   +1 more source

Influência do polimorfismo rs1801282 no gene PPARG associado ao sobrepeso e obesidade na população brasileira [PDF]

, 2020
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.O sobrepeso e a obesidade são um problema de saúde pública global com uma evidente predisposição genética ainda não totalmente esclarecida.
Castro, Gabriel Vaisam
core  

POLYMORPHISM PRO12ALA OF THE PPARG-2 GENE (rs1801282) IN CHILDREN WITH OBESITY

Medical science of Uzbekistan
Resume:  This article presents data from a study of the Pro12Ala polymorphism of the PPARG-2 gene in obese children. The study results are recommended for widespread implementation in the practice of pediatric hospital physicians. The aim of the work: to study the frequency of the Pro12Ala polymorphism of the PPARG 2 gene in children with different ...
Lilia Garifullina, Uktam Rustamov
openaire   +1 more source

Two SNPs (rs1801282 and -1279G/A) of PPARγ are associated with Parkinson's disease in a northern Chinese population

, 2020
Abstract Background: This study aimed to assess the association between PPARγ gene polymorphism and susceptibility to Parkinson’s disease (PD) in a northern Chinese population. Methods : We conducted a case-control study which including 391 outpatients with PD and 391 healthy matched individuals. All subject genotypes on PPARγ gene in rs3856806,
shanshan li, Li Xue, Huimin Wang, Qingwu Tian, Anmu Xie   +4 more
openaire   +1 more source

Association of gene polymorphisms with body weight changes in prediabetic patients [PDF]

, 2022
Recent research has demonstrated that Type 2 Diabetes (T2D) risk is influenced by a number of common polymorphisms, including MC4R rs17782313, PPARG rs1801282, and TCF7L2 rs7903146.
Medvedeva, Mariya S, Kiseleva, Tatyana A., Kiseleva, Tatyana A, Khasanova, Kamilya B., Khasanova, Kamilya B, Valeeva, Elena V., Egorova, Emiliya S., Pickering, Craig, Egorova, Emiliya S, Valeeva, Farida V, Valeeva, Elena V, Ahmetov, Ildus I., Ahmetov, Ildus I, Valeeva, Farida V., Medvedeva, Mariya S.   +14 more
core   +3 more sources

Population Pharmacokinetic and Pharmacodynamic Analysis of Voriconazole‐Induced Liver Injury in Chinese Lung Transplant Patients

Journal of Clinical Pharmacy and Therapeutics, Volume 2026, Issue 1, 2026.
Background Voriconazole (VCZ) served as primary therapy for invasive aspergillosis in lung transplant recipients. However, VCZ‐induced hepatotoxicity emerged as a frequent adverse effect that critically compromised postoperative management and complication prevention in this vulnerable population.
Dan Zhang, Wenwen Du, Wei Qin, Bo Li, Pengmei Li, Xiaoxing Wang, Wenqian Chen, Anjali Chauhan   +7 more
wiley   +1 more source