Results 41 to 50 of about 2,006 (194)
FABP-2 and PPAR-γ Haplotype as Risk Factors for Dyslipidemia in a Type 2 Diabetes Mellitus Population of Santa Rosa del Conlara, San Luis, Argentina [PDF]
, 2014 Introduction: Type 2 Diabetes Mellitus (T2DM) is a complex disorder caused by the interaction between genetic predisposition and environmental factors. Genetics plays an important role on lipid homeostasis. Many genes are involved in the lipid metabolism,
Fernandez, Gustavo +4 more
core +1 more source
Neural Regeneration Research, 2019 Two common polymorphisms of the peroxisome proliferator-activated receptor gamma (PPARG) gene, rs1801282 and rs3856806, may be important candidate gene loci affecting the susceptibility to ischemic stroke.
Yan-Zhe Wang +5 more
doaj +1 more source
Biology of Sport, 2021 Peroxisome proliferator-activated receptors (PPARs) have unique functions in energy metabolism regulation but are also involved in regulation of the inflammatory process and obesity.
Ewelina Maculewicz +14 more
doaj +1 more source
Lifestyle factors modify obesity risk linked to PPARG2 and FTO variants in an elderly population: a cross-sectional analysis in the SUN Project. [PDF]
, 2012 Genetic factors may interact with lifestyle factors to modify obesity risk. FTO and PPARG2 are relevant obesogenes. Our aim was to explore the effect of Pro12Ala (rs1801282) of PPARG2 and rs9939609 of FTO on obesity risk and to examine their interaction ...
Galbete, C. (Cecilia) +5 more
core +1 more source
EUREKA: Health Sciences, 2020 The aim: to investigate the metabolic effects of different treatment options in patients with obesity and concomitant non-alcoholic fatty liver disease (NAFLD) based on the presence of CG and GG genotypes PPARG rs1801282 (Pro12Ala) polymorphism in Ukrainians.
Vadym Shypulin +5 more
openaire +3 more sources
Genetic variants and the metabolic syndrome: a systematic review [PDF]
, 2011 Several candidate gene studies on the metabolic syndrome (MetS) have been conducted. However, for most single nucleotide polymorphisms (SNPs) no systematic review on their association with MetS exists.
Boer, J.M., Feskens, E.J.M., Povel, C.M.
core +3 more sources
Genome-wide scanning versus candidate gene approach in the genetic architecture of common diseases. [PDF]
, 2007 In the Nature 7 June issue, researchers from the Welcome Trust Case Control Consortium (WTCCC) reported the findings of a large genome-wide association (GWA) study of 14,000 cases of common diseases and 3000 controls studies revealing the role of several
Carlos J. Pirola, Silvia Sookoian
core +2 more sources
PPAR gamma pro12Ala polymorphism and type 2 diabetes: a study in a spanish cohort [PDF]
, 2014 Type 2 diabetes (T2D) is a disease whose occurrence is increasing prevalent in westernized civilizations and is responsible for the proliferation in the morbidity and total mortality of patients with cardiovascular diseases, worldwide.
Cieza Borrella, C +5 more
core +1 more source
Diabetic Medicine, Volume 37, Issue 11, Page 1879-1889, November 2020., 2020 Abstract Aims To examine the association between 24 literature‐based single nucleotide polymorphisms and diabetic kidney disease in Chinese people with type 2 diabetes. Methods and results Twenty‐four candidate diabetic kidney disease‐susceptible single nucleotide polymorphisms were genotyped in 208 participants with type 2 diabetes and diabetic kidney
J.‐F. Yang +16 more
wiley +1 more source
Association study of rs1801282 PPARG gene polymorphism and immune cells and cytokine levels in a Spanish pregnant women cohort and their offspring [PDF]
Journal of Biomedical Science, 2020 AbstractBackgroundPeroxisome proliferator activated receptor gamma (PPARG) belongs to the nuclear receptor superfamily functioning as transcription factors to regulate cellular differentiation, development and metabolism. Moreover, it has been implicated in the regulation of lipid metabolism, as well as the maturation of monocytes/macrophages and the ...
Maria García-Ricobaraza +8 more
openaire +6 more sources