Results 61 to 70 of about 1,103 (148)

Effect of PPAR-γ2 Gene Pro12Ala polymorphism (Rs1801282) and Vitamin D3 on glucose homeostasis in Type 2 diabetic subjects from Gujarat-India [PDF]

Molecular Cytogenetics, 2014
Background Pro12Ala polymorphism in PPAR-g2 gene is known to be involved in insulin sensitization and metabolic deregulation in Type 2 Diabetes (T2D) subject. Considering beneficial effects of Vitamin D3 in functional regulation of pancreatic-b cells, present population based study was designed to determine the association of Pro12Ala polymorphism with
Majumder, Avisek, Sheth, Frenny, Patel, Manan, Doshi, Bhavik, Shah, Navneet, Thankor, Premal, Vaidya, Rama, Sheth, Jayesh   +7 more
openaire   +1 more source

Association of the Genetic Polymorphisms in Transcription Factor 7-Like 2 and Peroxisome Proliferator-Activated Receptors-γ2 with Type 2 Diabetes Mellitus and Its Interaction with Obesity Status in Emirati Population

Journal of Diabetes Research, 2015
Background. Transcription factor 7-like 2 gene (TCF7L2) and peroxisome proliferator-activated receptors-γ2 (PPAR-γ2) have a profound effect on the incidence of type 2 diabetes mellitus (T2DM) and had previously been found to be associated with T2DM risk ...
Habiba Al-Safar, Ahmed Hassoun, Shaikha Almazrouei, Wala Kamal, Bachar Afandi, Naushad Rais   +5 more
doaj   +1 more source

Association of PPARG and LPIN1 gene polymorphisms with metabolic syndrome and type 2 diabetes [PDF]

Medicinski Glasnik, 2011
Aim Lipin 1 is a recently discovered multifunctional protein involvedin the metabolism of lipids, while PPAR?? is involved in adipocytedifferentiation, and regulation of lipid metabolism. Up to now, LPIN1 and PPARG gene polymorphisms have been associated
Tamer Bego, Tanja Dujic, Barbara Mlinar, Sabina Semiz, Maja Malenica, Besim Prnjavorac, Barbara Ostanek, Janja Marc, Adlija Čaušević   +8 more
doaj  

Ueg Week 2020 Poster Presentations

, 2020
United European Gastroenterology Journal, Volume 8, Issue S8, Page 144-887, October 2020.
wiley   +1 more source

Rs7903146 variant of TCF7L2 gene and rs18012824 variant of PPARG2 gene (Pro12Ala) are associated with type 2 diabetes mellitus in Novosibirsk population

Сахарный диабет, 2013
Aim.  To investigate the association of polymorphisms in TCF7L2 and PPARG2 genes with type 2 diabetes mellitus (T2DM) in Novosibirsk population. Materials and Methods.
Irina Arkad'evna Bondar', Maksim Leonidovich Filipenko, Olesya Yur'evna Shabel'nikova, Ekaterina Alexandrovna Sokolova   +3 more
doaj   +1 more source

Combined influence of polymorphic variants of PPAR-2 (rs1801282) and ACE (rs4646994) genes on the onset of non-alcoholic fatty liver disease in patients with essential arterial hypertension and obesity

Journal of Education, Health and Sport, 2018
Objective: to study a combined influence of polymorphic variants of PPAR-g2 (rs1801282) and ACE (rs4646994) genes on the onset of non-alcoholic fatty liver disease (NAFLD) in patients with essential arterial hypertension (EAH) and obesity. Materials and
Yu. M. Yarynych, L. P. Sydorchuk
doaj   +3 more sources

THE VALUE OF POLYMORPHISM RRO12ALA GENE PPARG IN VIOLATION OF LIPID PEROXIDATION AND ANTIOXIDANT PROTECTION IN PATIENTS WITH TYPE 2 DIABETES

Ukrainian Scientific Medical Youth Journal, 2016
Resume. The incidence of type 2 diabetes is increasing in Ukraine and worldwide. The severity of this disease is determined by the number of complications, which are based on lipid peroxidation (LPO).
V. Y. Mokrii, S. V. Ziablytsev, M. V. Cryshtal   +2 more
doaj   +1 more source

Lack of Genetic Associations of PPAR-γ and PGC-1α with Alzheimer's Disease and Parkinson's Disease with Dementia

Dementia and Geriatric Cognitive Disorders Extra, 2013
Background and Aims: Similar clinical and pathological features have been observed in Alzheimer's disease (AD) and Parkinson's disease with dementia (PDD).
Nobuto Shibata, Yumiko Motoi, Hiroyuki Tomiyama, Tohru Ohnuma, Bolati Kuerban, Katrin Tomson, Miwa Komatsu, Hiromi Shimazaki, Nobutaka Hattori, Heii Arai   +9 more
doaj   +1 more source

Association of FTO and PPARG polymorphisms with obesity in Portuguese women

Diabetes, Metabolic Syndrome and Obesity, 2013
Fábio Ferreira Carlos,1,2 José Silva-Nunes,3,4 Orfeu Flores,1 Miguel Brito,3 Gonçalo Doria,1 Luísa Veiga,3 Pedro Viana Baptista1 1Centro de Investigação em Genética Molecular Humana, Universidade Nova de ...
Ferreira Carlos F, Silva-Nunes J, Flores O, Brito M, Doria G, Veiga L, Baptista PV   +6 more
doaj  

The profile of selected single nucleotide polymorphisms in patients with hypertension and heart failure with preserved and mid-range ejection fraction

Scientific Reports, 2017
The study aimed to assess the clinical significance of selected single nucleotide polymorphisms (SNPs) in patients with diastolic heart failure (HF): inflammation [-174 G/C Interleukin -6 (IL-6) rs1800795, tumor necrosis factor (TNF)-608 G/A rs1800629 ...
Agata Bielecka-Dabrowa, Agata Sakowicz, Tadeusz Pietrucha, Małgorzata Misztal, Piotr Chruściel, Jacek Rysz, Maciej Banach   +6 more
doaj   +1 more source