Results 231 to 240 of about 5,884,585 (302)

Spatial Au+ Mapping Reveals a Self‐Amplifying Anti‐Tumor Immunity Loop Driven by Au(I) Complexes

open access: yesAdvanced Science, EarlyView.
The first report of spatial Au+ mapping of a representative gold complex (Au9). Macrophages, DCs, and tumor cells ranked as the top three in Au+ enrichment after Au9 treatment. Interestingly, Au9 treatment could induce ferroptosis and suppress cellular cholesterol, further eliciting a self‐amplifying anti‐tumor immunity loop.
Zhongren Xu   +5 more
wiley   +1 more source

Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma

open access: yesAdvanced Science, EarlyView.
Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul   +4 more
wiley   +1 more source

Ruthenium(II) Complex with 8-Hydroxyquinoline Exhibits Antitumor Activity in Breast Cancer Cell Lines. [PDF]

open access: yesCancers (Basel)
Khalifa A   +5 more
europepmc   +1 more source

A Versatile DNA‐Encoded Library Platform for the Discovery of Highly Cooperative Chemical Inducers of Proximity

open access: yesAdvanced Science, EarlyView.
We present a versatile DNA‐encoded library (DEL) platform designed for rapid library synthesis and subsequent screening for chemical inducers of proximity (CIPs) across various presenter proteins of choice. Applying this approach, we discovered a novel molecular glue‐like compound mediating CRBN‐BRD9 ternary complex formation with remarkable ...
Bingqi Tong   +11 more
wiley   +1 more source

Ruthenium(II) Polypyridyl Complexes Containing COUBPY Ligands as Potent Photosensitizers for the Efficient Phototherapy of Hypoxic Tumors. [PDF]

open access: yesJ Am Chem Soc
Abad-Montero D   +17 more
europepmc   +1 more source

Ruthenium(II) Lipid-Mimics Drive Lipid Phase Separation to Arouse Autophagy-Ferroptosis Cascade for Photoimmunotherapy. [PDF]

open access: yesAdv Sci (Weinh)
Zheng Y   +8 more
europepmc   +1 more source

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