Spatial Au+ Mapping Reveals a Self‐Amplifying Anti‐Tumor Immunity Loop Driven by Au(I) Complexes
The first report of spatial Au+ mapping of a representative gold complex (Au9). Macrophages, DCs, and tumor cells ranked as the top three in Au+ enrichment after Au9 treatment. Interestingly, Au9 treatment could induce ferroptosis and suppress cellular cholesterol, further eliciting a self‐amplifying anti‐tumor immunity loop.
Zhongren Xu +5 more
wiley +1 more source
Crystal structure and near-infrared emission of <i>trans</i>-di-chlorido-(di-meth-oxy-phenyl-phosphine)[4,4',4''-tris-(meth-oxy-carbon-yl)-2,2':6',2''-terpyridine]-ruthenium(II) monohydrate. [PDF]
Kinoshita T, Segawa H.
europepmc +1 more source
Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma
Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul +4 more
wiley +1 more source
Ruthenium(II) Complex with 8-Hydroxyquinoline Exhibits Antitumor Activity in Breast Cancer Cell Lines. [PDF]
Khalifa A +5 more
europepmc +1 more source
We present a versatile DNA‐encoded library (DEL) platform designed for rapid library synthesis and subsequent screening for chemical inducers of proximity (CIPs) across various presenter proteins of choice. Applying this approach, we discovered a novel molecular glue‐like compound mediating CRBN‐BRD9 ternary complex formation with remarkable ...
Bingqi Tong +11 more
wiley +1 more source
Host-Guest Interactions of Ruthenium(II) Arene Complexes with Cucurbit[7/8]uril. [PDF]
Roth E +3 more
europepmc +1 more source
Ruthenium(II) Polypyridyl Complexes Containing COUBPY Ligands as Potent Photosensitizers for the Efficient Phototherapy of Hypoxic Tumors. [PDF]
Abad-Montero D +17 more
europepmc +1 more source
Ruthenium(II) Lipid-Mimics Drive Lipid Phase Separation to Arouse Autophagy-Ferroptosis Cascade for Photoimmunotherapy. [PDF]
Zheng Y +8 more
europepmc +1 more source
Selective Targeting of Regulated Rhabdomyosarcoma Cells by Trinuclear Ruthenium(II)-Arene Complexes. [PDF]
Welsh A, Serala K, Prince S, Smith GS.
europepmc +1 more source
Visible light-induced ruthenium(ii)-catalyzed hydroarylation of unactivated olefins. [PDF]
Trienes S +4 more
europepmc +1 more source

