Results 171 to 180 of about 387,337 (354)

Isoquercetin and Zafirlukast Cooperatively Suppress Tumor Growth and Thromboinflammatory Signaling in a Xenograft Model of Ovarian Cancer

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Treatment using either the thiol isomerase inhibitor isoquercetin or zafirlukast lowers tissue factor levels, decreases VEGF, inhibits PD‐L1, and TMEM176B in a xenograft model of ovarian cancer. A combination of the two agents, at threefold lower concentrations than either drug, significantly enhanced the inhibition further, suggesting a dual action of
Justine A. Keovilay   +4 more
wiley   +1 more source

Natural Sweetener Stevioside‐Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 2, 14 January 2026.
This study addresses limitations of minoxidil (MXD) in treating androgenetic alopecia by using stevioside (STV) as a solubilizing agent and microneedle (MN) material. STV enhanced MXD's solubility and skin absorption, leading to improved drug delivery and significant hair regrowth in animal models, demonstrating strong potential for AGA treatment ...
Junying Zhang   +7 more
wiley   +1 more source

Optimization of bioactive compound extraction from Brazilian forest bark species: effects of solvent mixtures on metal ion chelation and urease enzyme inhibition

open access: yesBiofuels, Bioproducts and Biorefining, Volume 20, Issue 1, Page 99-109, January/February 2026.
Abstract The bark of forest species is a resource with a high concentration of bioactive compounds that have antioxidant, chelating and antimicrobial properties. Bioprospecting bioactive compounds from bark can generate income for local communities and contribute to the social and economic development of rural areas, especially in regions where ...
Mário Sérgio Lorenço   +6 more
wiley   +1 more source

Antioxidant Activity and Potential Cholesterol Modulating Effect of Punica granatum L. Peel Hydroethanolic Extract

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
Punica granatum peel extract is rich in phenolic compounds, exhibits strong antioxidant activity, and modulates the expression of PCSK9 and LDL receptors. Collectively, these findings suggest a potential cardioprotective effect of the extract. ABSTRACT Lipoprotein metabolism is regulated by several key proteins, notably proprotein convertase subtilisin/
Raja Chaaba   +9 more
wiley   +1 more source

Zinc oxide nanorod/rutin modified electrode for the detection of Thiourea in real samples

open access: gold, 2023
Md. Abdul Khaleque   +7 more
openalex   +1 more source

Exploitation of the Antibacterial Activity of Micromeria graeca L. Extracts From Northern Morocco

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
Among the various extraction techniques investigated, the methanolic ultrasound‐assisted extract (MGME‐UAE) of Micromeria graeca L exhibited the strongest bactericidal effect, selectively inhibiting Proteus mirabilis (inhibition zone 12.7 ± 0.6 mm; MIC = 6.25 mg/mL).
Houda Chtibi   +7 more
wiley   +1 more source

Rutin Exhibits In-Vitro Anticoagulant Activity in Human Blood Samples by Prolonging Coagulation Pathway Times. [PDF]

open access: yesGlob Adv Integr Med Health
Palikhey A   +5 more
europepmc   +1 more source

Evaluation of Antibacterial Activity, Chromatographic Analysis for Rutin and Quercetin Quantification Using HPLC-UV-Vis from the Hydro-Alcoholic Extract Obtained from Bidens pilosa Linné

open access: gold, 2020
Carlos Pinilla   +5 more
openalex   +1 more source

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