Results 21 to 30 of about 8,452 (228)

Real world evidence (RWE) – a disruptive innovation or the quiet evolution of medical evidence generation? [version 2; referees: 2 approved]

F1000Research, 2018
Stakeholders in healthcare are increasingly turning to real world evidence (RWE) to inform their decisions, alongside evidence from randomized controlled trials.
Sajan Khosla, Robert White, Jesús Medina, Mario Ouwens, Cathy Emmas, Tim Koder, Gary Male, Sandra Leonard   +7 more
doaj   +1 more source

Awareness, Knowledge, and Utility of RCT Data vs RWE: Results From a Survey of US Cardiologists: Real-world Evidence in Clinical Decision Making

Clinical Medicine Insights: Cardiology, 2020
Real-world evidence (RWE) provides a potential rich source of additional information to the body of data available from randomized clinical trials (RCTs), but there is a need to understand the strengths and limitations of RWE before it can be applied to ...
Todd C Villines, Mark J Cziraky, Alpesh N Amin   +2 more
doaj   +1 more source

Methods for the inclusion of real-world evidence in network meta-analysis

BMC Medical Research Methodology, 2021
Background Network Meta-Analysis (NMA) is a key component of submissions to reimbursement agencies world-wide, especially when there is limited direct head-to-head evidence for multiple technologies from randomised controlled trials (RCTs).
David A. Jenkins, Humaira Hussein, Reynaldo Martina, Pascale Dequen-O’Byrne, Keith R. Abrams, Sylwia Bujkiewicz   +5 more
doaj   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

RWE light house project case study: Moerdijk high hydrogen conversion [PDF]

E3S Web of Conferences
Hydrogen is considered a key technological solution to decarbonise many heavy industries, including in the power sector to fuel Gas turbines (GT). Typically, GTs operate on carbonaceous fuels such as natural gas, which produce CO2 emissions.
Bain James, Hoeben Jappe, Skudder Rachel, Cretegny Laurent, Delaval Frederic, Feher Peter, Codron Fabien   +6 more
doaj   +1 more source

Identifying Themes of Right-Wing Extremism in Hindutva Discourse on Twitter

Social Media + Society, 2023
Hindutva, the core political ideology of India’s current ruling party, the Bharatiya Janata Party (BJP), seeks to transform constitutionally secular India into a Hindu Rashtra (“Hindu nation”).
Piyush Ghasiya, Georg Ahnert, Kazutoshi Sasahara   +2 more
doaj   +1 more source

EA3: A softmax algorithm for evidence appraisal aggregation.

PLoS ONE, 2021
Real World Evidence (RWE) and its uses are playing a growing role in medical research and inference. Prominently, the 21st Century Cures Act-approved in 2016 by the US Congress-permits the introduction of RWE for the purpose of risk-benefit assessments ...
Francesco De Pretis, Jürgen Landes
doaj   +1 more source

The concept of an ideal real-world evidence study: industry opinion

Реальная клиническая практика: данные и доказательства
Introduction. Real-world evidence (RWE) plays a critical role in pharmaceutical companies at all stages of a medical product’s life cycle. Contract research organizations and research infrastructure suppliers ensure that RWE studies.
T. A. Goldina, Yu. V. Khomitskaya
doaj   +1 more source

Expression of FcγRIIb in the lungs after RWE challenge. [PDF]

, 2013
(A) Balb/c mice sensitized with RWE and challenged with either RWE (filled squares) or PBS (open diamond). Mice were sacrificed 1, 4, 24, 72 and 240 h after challenge, lungs were collected and RNA was extracted.
Alexander Kurosky (333545), Istvan Boldogh (16539), Hiroki Murai (333524), Nilesh Dharajiya (333536), Sanjiv A. Sur (366874), Swapnil V. Vaidya (366865), Victor Cardenas (366868)   +6 more
core   +1 more source

Die RWE-E.ON-Transaktion – Eine Analyse der Auswirkungen auf den Wettbewerb unter Berücksichtigung des Kartellrechts [PDF]

, 2021
Im März 2018 veröffentlichten die beiden Energieunternehmen RWE und E.ON eine gemeinsame Pressemitteilung, die die Transaktion beider Konzerne beinhaltete. Dabei übernimmt E.ON das Innogy Geschäft von RWE.
Fritsch, Tim
core   +1 more source