Results 131 to 140 of about 2,484 (221)

Transcriptomic analysis of the HPT axis in a model of oligoasthenozoospermia induced by Adenine in rats

Experimental and Molecular Pathology
Male infertility is most commonly caused by oligozoospermia, and its pathogenesis is still poorly understood at the molecular level. This study used RNA sequencing (RNA-Seq) technology to identify candidate genes and regulatory pathways that regulate ...
Nan Yang, Xiao-ge Wei, Kaiying Li, Fei Wang, Fei Song, Wenjing Sun, Yan Wang, Zhenning Zhao, Jing Mu, Huisheng Ma   +9 more
doaj   +1 more source

Relaxin Activates Peroxisome Proliferator-activated Receptor ƴ (PPAR\u3csub\u3eƴ\u3c/sub\u3e) through a Pathway Involving PPAR \u3csub\u3eƴ\u3c/sub\u3e Coactivator 1α (PGC1α) [PDF]

, 2015
Background: Relaxin activates peroxisome proliferator-activated receptorƴ (PPARƴ) by an unknown PPARƴ ligandindependent mechanism. Results: Expression of PPARƴ coactivator 1α (PGC1α) was increased by relaxin through distinct signaling pathways ...
Bennett, Robert G., Simpson, Ronda L., Singh, Sudhir K.   +2 more
core   +1 more source

RXFP1-LDLa linker

, 2016
Ashish Sethi, Paul R. Gooley
openalex   +1 more source

Serelaxin: A Novel Therapy for Acute Heart Failure with a Range of Hemodynamic and Non-Hemodynamic Actions [PDF]

, 2014

core   +1 more source

AB0185 Altered expression of relaxin receptor rxfp1/lgr7 in dermal fibroblasts contributes to the inefficacy of relaxin-based anti-fibrotic treatments in systemic sclerosis [PDF]

, 2018
Claudio Corallo, Maurizio Cutolo, Stefano Soldano, Sara Cheleschi, Antonio Fioravanti, Anna Maria Pinto, Alessandra Renieri, Ranuccio Nuti, N. Giordano   +8 more
openalex   +1 more source

Relaxin deficiency results in increased expression of angiogenesis- and remodelling-related genes in the uterus of early pregnant mice but does not affect endometrial angiogenesis prior to implantation [PDF]

, 2016

core   +1 more source

High-depth whole-genome sequencing identifies structure variants, copy number variants and short tandem repeats associated with Parkinson’s disease

npj Parkinson's Disease
While numerous single nucleotide variants and small indels have been identified in Parkinson’s disease (PD), the contribution of structural variants (SVs), copy number variants (CNVs), and short tandem repeats (STRs) remains poorly understood.
Chaodong Wang, Hankui Liu, Xu-Ying Li, Jinghong Ma, Zhuqin Gu, Xiuli Feng, Shu Xie, Bei-Sha Tang, Shengdi Chen, Wei Wang, Jian Wang, Jianguo Zhang, Piu Chan   +12 more
doaj   +1 more source

SHROOM3 is a novel candidate for heterotaxy identified by whole exome sequencing [PDF]

, 2011
Muhammad Tariq, John W Belmont, Seema Lalani, Teresa Smolarek, Stephanie M Ware   +4 more
core   +1 more source

The relaxin family peptide receptor 1, RXFP1, is differentially expressed in non-small cell lung cancer and associates with patient survival.

, 2020
Shahan Mamoor
openalex   +1 more source

The role of the relaxin receptor RXFP1 in brain cancer

, 2013
Relaxin (RLN2) promotes cell migration/invasion, cell growth, and neoangiogenesis through binding to the relaxin receptor RXFP1 in many types of cancers. However, there have been no studies to determine the role of this system in brain tumors, especially in Glioblastoma Multiforme (GB), the most lethal primary brain tumor in adults.
openaire   +1 more source