Results 161 to 170 of about 2,075 (199)

Effects of <i>INSL3</i> and <i>WNT2B</i> gene polymorphisms on seasonal reproductive traits of Xinjiang Qira black sheep, Kazakh sheep and Duolang sheep. [PDF]

Anim Biotechnol
Bi J, Yiming S, Li J, Wang Q, Zhai M, Cao S, Zhu M, Yang H.   +7 more
europepmc   +1 more source

Effect of pregnancy hormones on pain perception in the peripartum period: A narrative review. [PDF]

J Anaesthesiol Clin Pharmacol
Malviya AK, Gupta A, Kumar V, Gupta J, Deepika, Khanna P.   +5 more
europepmc   +1 more source

Unveiling the Causal Relationship of Cardiovascular Burden in Primary Aldosteronism by Genome-Wide Association and Mendelian Randomization: A Possible Solution? [PDF]

J Am Heart Assoc
Tsai CH, Lai TS, Lin YH.
europepmc   +1 more source

Immune cell uptake of glycinated nanoparticles conjugated to anti-fibrotic peptides enables their prolonged activity and oral administration. [PDF]

J Biomed Sci
Somanader-Livera DVN, Wei C, Wang C, Li Y, Ferens D, Salimova E, Selomulya C, Hossain MA, Samuel CS, Chakraborty A.   +9 more
europepmc   +1 more source

Maternal Fed Zinc-Deficient Diet: Effects on Relaxin Family Peptides and Oxidant System in the Testis and Liver Tissue of Male Offspring. [PDF]

Biol Trace Elem Res
Kose H, Sivrikaya A, Menevse E.
europepmc   +1 more source

INSL3/RXFP2 Signaling in Testicular Descent [PDF]

Annals of the New York Academy of Sciences, 2009
Mutations of the insulin‐like peptide 3 (INSL3) hormone or its receptor, RXFP2, cause intraabdominal cryptorchidism in male mice. Specific RXFP2 expression in mouse gubernacula was detected at embryonic day 14.5 and markedly increased after birth in the developing cremaster muscle, as well as in the epididymis and testicular Leydig and germ cells ...
Alberto Ferlin, John D Wade, Carlo Foresta   +2 more
exaly   +13 more sources

The Importance of Tryptophan B28 in H2 Relaxin for RXFP2 Binding and Activation [PDF]

International Journal of Peptide Research and Therapeutics, 2012
H2 relaxin (relaxin) is a member of the insulin–relaxin superfamily and exhibits several non-reproductive functions in addition to its well-known properties as a pregnancy hormone. Over the years, the therapeutic potential of relaxin has been examined for a number of conditions.
John D Wade, Frances Separovic, Mohammed Akhter Hossain   +2 more
exaly   +5 more sources

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Modeling the Primary Hormone‐Binding Site of RXFP1 and RXFP2

Annals of the New York Academy of Sciences, 2009
The primary binding sites of the relaxin and insulin‐like peptide 3 (INSL3) receptors, RXFP1 and RXFP2, are found within the leucine‐rich repeats (LRRs) of the ectodomains. Specific B‐chain residues in the peptides interact with residues in the inner β‐sheets of the LRRs of the receptors.
Daniel J Scott, Roger J Summers
exaly   +3 more sources

A missense mutation in LRR8 of RXFP2 is associated with cryptorchidism

Mammalian Genome, 2010
Using genome-wide mutagenesis with N-ethyl-N-nitrosourea (ENU), a mouse mutant with cryptorchidism was identified. Genome mapping and exon sequencing identified a novel missense mutation (D294G) in Relaxin/insulin-like family peptide receptor 2 (Rxfp2).
Alexander I Agoulnik, James L Jameson, Roger J Summers   +2 more
exaly   +3 more sources

Resolving the Unconventional Mechanisms Underlying RXFP1 and RXFP2 Receptor Function

Annals of the New York Academy of Sciences, 2009
The receptors for relaxin and insulin‐like peptide 3 (INSL3) are now well‐characterized as the relaxin family peptide (RXFP) receptors RXFP1 and RXFP2, respectively. They are G‐protein‐coupled receptors (GPCRs) with closest similarity to the glycoprotein hormone receptors, with both containing large ectodomains with 10 leucine‐rich repeats (LRRs ...
Daniel J Scott, Emma J Petrie, Roger J Summers   +2 more
exaly   +3 more sources