Results 121 to 130 of about 31,472 (217)

Development and analytical validation of a targeted short‐read next generation sequencing‐based pharmacogenetic panel for comprehensive variant detection

British Journal of Pharmacology, Volume 183, Issue 16, Page 4735-4760, August 2026.
Abstract Background and Purpose Genomic profiling of patients for genetic variants that modify the effect of specific medications has many benefits, including the possibility of avoiding toxicities and ensuring an adequate effect of the medication. Our intention was to develop a comprehensive, high‐quality pharmacogenetic test panel for clinical use ...
Anna Gréen, Nils Johan Fredriksson, Michael Andresen, Jon Jonasson, Malin Lindqvist Appell, Henrik Gréen   +5 more
wiley   +1 more source

Clustering Properties of Neuronal Ryanodine Receptor 2 and Remodeling in the APP/PS1 Mouse Model of Alzheimer's Disease. [PDF]

Acta Physiol (Oxf)
Munro ML, Silva RV, Ohline SM, Khaing EP, Chan JA, Ibrahim MF, Tausi TF, Abraham WC, Jones PP.   +8 more
europepmc   +1 more source

Gβγ subunit activation of KV7 and BKCa channels underlies calcitonin gene‐related peptide vasorelaxation in myogenic rat coronary resistance arteries

British Journal of Pharmacology, Volume 183, Issue 16, Page 5018-5032, August 2026.
Abstract Background and Purpose CGRP is a potent, clinically relevant coronary vasodilator known to play a role in cardioprotection. Here, we investigated the precise intracellular signalling pathways leading to vasodilation in small coronary arteries.
Lucy A. Donovan, JinHeng Lin, Milind Khashu, Christopher J. Garland, Kim A. Dora   +4 more
wiley   +1 more source

Ryanodine Receptor Ca²⁺ Leak-Induced Redistribution of Ca²⁺ in Dystrophic mdx Mouse Muscle. [PDF]

Acta Physiol (Oxf)
Gaglianone RB, Lamboley CR, Dick T, Meizoso-Huesca A, Singh DP, Launikonis BS.   +5 more
europepmc   +1 more source

Unraveling the ryanodine receptor

Biophysical Journal, 1994
openaire   +2 more sources

Ryanodine Receptors [PDF]

Biophysical Journal, 2008
openaire   +1 more source

Sparks of life: Enabling multi‐scale investigations of pro‐arrhythmic calcium‐handling abnormalities

The Journal of Physiology, EarlyView.
Melania Buonocunto, Jordi Heijman
wiley   +1 more source

The interplay between pulsatility, sympathetic regulation and renal physiology: Implications for left ventricular assist devices

Experimental Physiology, Volume 111, Issue 8, Page 3514-3524, 1 August 2026.
Abstract Left ventricular assist devices have gained traction both as a bridge therapy and as a destination therapy in the management of heart failure. Many of these devices reinstate blood flow in a continuous manner as opposed to the pulsatile flow present in normal physiology.
Tania Warnakulasuriya, Zaid Bahi, Rohit Ramchandra   +2 more
wiley   +1 more source

Potentiation of ryanodine receptor-mediated calcium release by MAPK is responsible for epidermal transformation and carcinogenesis. [PDF]

Proc Natl Acad Sci U S A
Wang P, Cleveland KH, Shahid A, Rathnayaka C, Amirrad F, Song Z, Estillore JP, Wang R, Back TG, Chen SRW, Huang Y.   +10 more
europepmc   +1 more source

Mechanisms underlying gastric antral slow waves – a human perspective

The Journal of Physiology, EarlyView.
Dirk F. van Helden
wiley   +1 more source