Results 121 to 130 of about 32,504 (219)
Type-1 Ryanodine Receptor Plays an Important Role in Cardiac Hypertrophy and Heart Failure by Increasing Type-2 Ryanodine Receptor-Mediated Calcium Release. [PDF]
Wang YX +6 more
europepmc +1 more source
ABSTRACT Introduction Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a potentially life‐threatening arrhythmic disorder typically treated with beta‐blockers and, occasionally, with flecainide. Methods All patients underwent genetic testing, electrocardiogram, echocardiogram, and exercise testing.
Fernando Wangüemert‐Perez +9 more
wiley +1 more source
Ryanodine Receptor 1 Is Dispensable for CD4<sup>+</sup> T-Cell Differentiation and Effector Function in Intestinal Inflammation Models. [PDF]
Dostiar Tabrizi S +14 more
europepmc +1 more source
SUMMARY The typical nucleotide‐binding leucine‐rich repeat (NLR) proteins, such as TIR‐NBS‐LRR (TNL) and CC‐NBS‐LRR (CNL), are known to be engaged in effector‐triggered immunity (ETI). However, several atypical resistance (R) proteins with truncated NLR domains or with nonclassical domains are emerging to be key regulators in plant immunity.
Zikai Zhou +12 more
wiley +1 more source
A new Fight-or-Flight Pacemaker Mechanism via Ryanodine Receptor abundance and superclustering. [PDF]
Ventura Subirachs V +6 more
europepmc +1 more source
Circular RNAs: Unlocking new avenues in cardiometabolic disease management
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor +4 more
wiley +1 more source
Clustering Properties of Neuronal Ryanodine Receptor 2 and Remodeling in the APP/PS1 Mouse Model of Alzheimer's Disease. [PDF]
Munro ML +8 more
europepmc +1 more source
Integrative simulation analysis of myocardial ischaemia–reperfusion injury
Abstract figure legend A comprehensive mathematical model of ventricular myocyte was developed to gain insights into the mechanisms underlying cardiac ischaemia–reperfusion injury. The model integrates excitation–contraction (E–C) coupling, cytosolic and mitochondrial pH regulation, pH dependence of major E–C coupling components and cellular energy ...
Takao Shimayoshi +2 more
wiley +1 more source

