Results 161 to 170 of about 2,365,951 (330)

Mitochondria and neuroprotection in stroke: Cationic arginine-rich peptides (CARPs) as a novel class of mitochondria-targeted neuroprotective therapeutics [PDF]

, 2018
Stroke is the second leading cause of death globally and represents a major cause of devastating long-term disability. Despite sustained efforts to develop clinically effective neuroprotective therapies, presently there is no clinically available ...
Anderton, Ryan S, Knuckey, Neville W, MacDougall, Gabriella, Mastaglia, Frank L, Meloni, Bruno P   +4 more
core   +1 more source

Current Trends in Duchenne Muscular Dystrophy Research and Therapy: 3D Cardiac Modelling

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, presents a multifaceted challenge that affects both skeletal muscle function and cardiomyocyte homeostasis, causing progressive degeneration and life‐threatening cardiac complications by adolescence.
Marta Przymuszała, Marta Białobrzeska, Józef Dulak, Urszula Florczyk‐Soluch   +3 more
wiley   +1 more source

Understanding CPVT pathogenic mechanisms based on mutation location within RyR2: towards personalized medicine?

The Journal of Physiology, EarlyView.
Jean‐Pierre Benitah, Esther Zorio, Ana María Gómez   +2 more
wiley   +1 more source

Ryanodine receptor in heart failure: potential therapeutic sites.

Revista Cubana de Cardiología y Cirugía Cardiovascular, 2011
La insuficiencia cardíaca (IC) contribuye de manera importante a la morbilidad y mortalidad por enfermedades cardíacas. Las anomalías en el manejo del Ca2+ tienen un papel preponderante en el desarrollo de la IC.
Guy Vassort
doaj  

Ion channels: structural basis for function and disease. [PDF]

, 1996
Ion channels are ubiquitous proteins that mediate nervous and muscular function, rapid transmembrane signaling events, and ionic and fluid balance. The cloning of genes encoding ion channels has led to major strides in understanding the mechanistic basis
Goldstein, SA
core   +1 more source

3R0900 Simultaneous measurement of electrical and optical properties of single molecule of cardiac ryanodine receptor

, 2002
Yûkô Takeuchi, Toru Ide, Takaaki Aoki, Toshio Yanagida   +3 more
openalex   +2 more sources

Calcium puffs are generic InsP₃-activated elementary calcium signals and are downregulated by prolonged hormonal stimulation to inhibit cellular calcium responses [PDF]

, 2001
Elementary Ca2+ signals, such as "Ca2+ puffs", which arise from the activation of inositol 1,4,5-trisphosphate receptors, are building blocks for local and global Ca2+ signalling.
Berridge, Michael J., Bootman, Martin D., De Smedt, Humbert, de Smet, Patrick, Holmes, Andrew, Lipp, Peter, Missiaen, Ludwig, Parys, Jan B., Thomas, David, Thuring, Jan, Tovey, Stephen C., Young, Kenneth W.   +11 more
core  

Ryanodine Receptor Structure and Function in Health and Disease.

Sub-cellular biochemistry, 2018
Gaetano Santulli, Daniel R. Lewis, Amédée des Georges, A. Marks, J. Frank   +4 more
semanticscholar   +1 more source

Small current, big potential: bridging mechanistic insight of the SK channel with translational promise

The Journal of Physiology, EarlyView.
Yang Zheng, Miao Zhang, Nipavan Chiamvimonvat   +2 more
wiley   +1 more source

Ryanodine receptor and capacitative Ca2+ entry in fresh preglomerular vascular smooth muscle cells [PDF]

, 2000
Susan K. Fellner, William J. Arendshorst
openalex   +1 more source