Results 41 to 50 of about 2,684,234 (246)

Pre-Slaughter Stress Affects Ryanodine Receptor Protein Gene Expression and the Water-Holding Capacity in Fillets of the Nile Tilapia.

PLoS ONE, 2015
Current study evaluated the effect of pre-slaughter stress on serum cortisol levels, pH, colorimetry, water-holding capacity (WHC) and gene expression of ryanodine receptors (RyR1 and RyR3) in the Nile tilapia.
Elenice S R Goes, Jorge A F Lara, Eliane Gasparino, Ana P Del Vesco, Marcio D Goes, Luiz Alexandre Filho, Ricardo P Ribeiro   +6 more
doaj   +1 more source

Role of Na+-K+-2Cl- Cotransporter 1 in Phenylephrine-Induced Rhythmic Contraction in the Mouse Aorta: Regulation of Na+-K+-2Cl- Cotransporter 1 by Ca2+ Sparks and KCa Channels

Cellular Physiology and Biochemistry, 2015
Background/Aims: Vasoconstrictor-induced rhythmic contraction of arteries or veins has been observed both in vivo and in vitro. Many studies have reported that gap junctions, ryanodine receptors, Na+, K+-ATPase and other factors are involved in ...
Bing Shen, Jie Fu, Jizheng Guo, Jie Zhang, Xia Wang, Xiang Pan, Meihua Chen, Yifan Zhou, Min Zhu, Juan Du   +9 more
doaj   +1 more source

Ryanodine receptors

Channels, 2014
ISSN: 1933-6950 (Print) 1933-6969 (Online) Journal homepage: http://www.tandfonline.com/loi/kchl20 Ryanodine receptors Mounia Chami & Frédéric Checler To cite this article: Mounia Chami & Frédéric Checler (2014) Ryanodine receptors, Channels, 8:3, 168 ...
M. Chami, F. Checler
semanticscholar   +1 more source

Single Amino Acid Changes in the Ryanodine Receptor in the Human Population Have Effects In Vivo on Caenorhabditis elegans Neuro-Muscular Function

Frontiers in Genetics, 2020
The ryanodine receptor mediates intracellular calcium ion release with excitation of nerve and muscle cells. Ryanodine receptor missense variants cause a number of myopathologies, such as malignant hyperthermia, and have been linked with various ...
Brittany Graham, Marie-Anne Shaw, Ian A. Hope   +2 more
doaj   +1 more source

Ryanodine receptors, calcium signaling and regulation of vascular tone in the cerebral parenchymal microcirculation

Microcirculation, 2013
The cerebral blood supply is delivered by a surface network of pial arteries and arterioles from which arise (parenchymal) arterioles that penetrate into the cortex and terminate in a rich capillary bed.
F. Dabertrand, Mark T Nelson, J. Brayden
semanticscholar   +1 more source

Dysfunctional ryanodine receptors in the heart: New insights into complex cardiovascular diseases

Journal of Molecular and Cellular Cardiology, 2013
Calcium dependent signaling is highly regulated in cardiomyocytes and determines the force of cardiac muscle contraction. The cardiac ryanodine receptors (RyR2) play important roles in health and disease. Modulation of RyR2 by phosphorylation is required
S. Marx, A. Marks
semanticscholar   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

Ryanodine Receptors: Structure and Function*

Journal of Biological Chemistry, 2012
Ryanodine receptors (RyRs) are huge ion channels that are responsible for the release of Ca2+ from the sarco/endoplasmic reticulum. RyRs form homotetramers with a mushroom-like shape, consisting of a large cytoplasmic head and transmembrane stalk.
F. van Petegem
semanticscholar   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Structural and functional conservation of key domains in InsP3 and ryanodine receptors

Nature, 2012
Inositol-1,4,5-trisphosphate receptors (InsP3Rs) and ryanodine receptors (RyRs) are tetrameric intracellular Ca2+ channels. In each of these receptor families, the pore, which is formed by carboxy-terminal transmembrane domains, is regulated by signals ...
M. Seo, S. Velamakanni, N. Ishiyama, P. Stathopulos, Ana M. Rossi, Samir A. Khan, Philippa Dale, Congmin Li, J. Ames, M. Ikura, C. Taylor   +10 more
semanticscholar   +1 more source