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Calcium Release Channels: Structure and Function of IP3 Receptors and Ryanodine Receptors.
Physiological Reviews, 2021 Ca2+-release channels are giant membrane proteins that control the release of Ca2+ from the endoplasmic and sarcoplasmic reticulum. The two members, ryanodine receptors (RyRs) and inositol-1,4,5-trisphosphate Receptors (IP3Rs), are evolutionarily related
Kellie A. Woll, F. van Petegem
semanticscholar +1 more source
Ryanodine Receptors Selectively Interact with L Type Calcium Channels in Mouse Taste Cells. [PDF]
PLoS ONE, 2013 INTRODUCTION:WE REPORTED THAT RYANODINE RECEPTORS ARE EXPRESSED IN TWO DIFFERENT TYPES OF MAMMALIAN PERIPHERAL TASTE RECEPTOR CELLS: Type II and Type III cells. Type II cells lack voltage-gated calcium channels (VGCCs) and chemical synapses.
Michelle R Rebello +2 more
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Ryanodine Receptors in Liver [PDF]
Journal of Biological Chemistry, 2006 The ryanodine receptor has been mainly regarded as the Ca2+ release channel from sarcoplasmic reticulum controlling skeletal and cardiac muscle contraction. However, many studies have shown that it is widely expressed, with functions not restricted to muscular contraction. This study examined whether ryanodine receptor plays a role in calcium signaling
Nicola, Pierobon +3 more
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Ryanodine Receptor Patents [PDF]
Recent Patents on Biotechnology, 2012 Research over the past two decades has implicated dysfunction of the ryanodine receptor (RyR), a Ca(2+) release channel on the sarcoplasmic reticulum (SR) required for excitation-contraction (EC) coupling, in the pathogenesis of cardiac and skeletal myopathies.
Alexander, Kushnir, Andrew R, Marks
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Calcium-release channels in paramecium. Genomic expansion, differential positioning and partial transcriptional elimination. [PDF]
PLoS ONE, 2011 The release of Ca²⁺ from internal stores is a major source of signal Ca²⁺ in almost all cell types. The internal Ca²⁺ pools are activated via two main families of intracellular Ca²⁺-release channels, the ryanodine and the inositol 1,4,5-trisphosphate ...
Eva-Maria Ladenburger, Helmut Plattner
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Ryanodine Receptor Adaptation [PDF]
The Journal of General Physiology, 2000 In the heart, depolarization during the action potential activates voltage-dependent Ca2+ channels that mediate a small, localized Ca2+ influx (ICa). This small Ca2+ signal activates specialized Ca2+ release channels, the ryanodine receptors (RyRs), in the sarcoplasmic reticulum (SR).
M, Fill +5 more
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Ryanodine receptor channelopathies [PDF]
Pflügers Archiv - European Journal of Physiology, 2010 Ryanodine receptors (RyR) are intracellular Ca2+-permeable channels that provide the sarcoplasmic reticulum Ca2+ release required for skeletal and cardiac muscle contractions. RyR1 underlies skeletal muscle contraction, and RyR2 fulfills this role in cardiac muscle.
Matthew J, Betzenhauser, Andrew R, Marks
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Frontiers in Physiology, 2021 Urothelial cells have been implicated in bladder mechanosensory transduction, and thus, initiation of the micturition reflex. Cell deformation caused by tension forces at an air-liquid interface (ALI) can induce an increase in intracellular Ca2 ...
Jiliang Wen +7 more
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European Journal of Translational Myology, 2016 Rabbit muscle vesicles derived from sarcoplasmic reticulum were used as a material in studying networks of ryanodine receptors by cryo electron tomography. Three-dimensional analysis reveals the dynamical features of these networks. It was found that the
Hongli Hu, Xing Meng
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The neuroprotective mechanism of cinnamaldehyde against amyloid-β in neuronal SHSY5Y cell line: The role of N-methyl-D-aspartate, ryanodine, and adenosine receptors and glycogen synthase kinase-3β [PDF]
Avicenna Journal of Phytomedicine, 2019 Objective: Cinnamaldehyde may be responsible for some health benefits of cinnamon such as its neuroprotective effects. We aimed to investigate the cinnamaldehyde neuroprotective effects against amyloid beta (Aβ) in neuronal SHSY5Y cells and evaluate the ...
Masoumeh Emamghoreishi +3 more
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