Results 21 to 30 of about 15,708 (115)
Polyglutamine Tract Expansion Increases S-Nitrosylation of Huntingtin and Ataxin-1. [PDF]
PLoS ONE, 2016 Expansion of the polyglutamine (polyQ) tract in the huntingtin (Htt) protein causes Huntington's disease (HD), a fatal inherited movement disorder linked to neurodegeneration in the striatum and cortex.
Chun-Lun Ni +8 more
doaj +1 more source
Phytohormonal Regulation Through Protein S-Nitrosylation Under Stress
Frontiers in Plant Science, 2022 The liaison between Nitric oxide (NO) and phytohormones regulates a myriad of physiological processes at the cellular level. The interaction between NO and phytohormones is mainly influenced by NO-mediated post-translational modifications (PTMs) under ...
Anjali Pande +9 more
doaj +1 more source
S-nitrosylation of fatty acid synthase regulates its activity through dimerization[S]
Journal of Lipid Research, 2016 NO regulates a variety of physiological processes, including cell proliferation, differentiation, and inflammation. S-nitrosylation, a NO-mediated reversible protein modification, leads to changes in the activity and function of proteins.
Min Sik Choi +5 more
doaj +1 more source
Communications Biology, 2022 Liu et al. identify catalase as a target of S-nitrosylation by GSNOR and the specific sites of S-nitrosylation critical for its role in regulating secondary metabolite production in Ganoderma lucidum under heat stress.
Rui Liu +8 more
doaj +1 more source
Cell Reports, 2020 Summary: The regulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) trafficking affects multiple brain functions, such as learning and memory.
George K.E. Umanah +20 more
doaj +1 more source
S‐Nitrosoglutathione Reductase Deficiency Causes Aberrant Placental S‐Nitrosylation and Preeclampsia
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Preeclampsia, a leading cause of maternal and fetal mortality and morbidity, is characterized by an increase in S‐nitrosylated proteins and reactive oxygen species, suggesting a pathophysiologic role for dysregulation in nitrosylation and ...
Shathiyah Kulandavelu +11 more
doaj +1 more source
Angewandte Chemie, EarlyView.Re‐envisioning the Ligandable Proteome: Reactive Metallo‐Scaffolds (r‐mS) combine non‐covalent protein engagement by a metallo‐scaffold with covalent cysteine capture through a tethered chloroacetamide warhead. Chemoproteomic profiling reveals unique enzyme engagement including ligases, kinases and methyltransferases, highlighting opportunities for ...
Jessica E. Waters +15 more
wiley +2 more sources
Agronomy, 2023 Nitric oxide (NO) modulates plant response by post-translationally modifying proteins, mainly through S-nitrosylation. Ascorbate peroxidase (APX) in the ascorbate-glutathione (AsA-GSH) cycle participates in the removal of hydrogen peroxide (H2O2 ...
Chuntao Lv +5 more
doaj +1 more source
Redox Biology, 2022 Background: s: Hyperhomocysteinemia (HHcy) is one of risk factors for vascular cognitive impairment (VCI). GTP cyclohydrolase 1 (GCH1) deficiency is critical to oxidative stress in vascular dysfunction.
Ya-Ling Yin +12 more
doaj +1 more source
iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin
BMC Musculoskeletal Disorders, 2020 Background Previous research indicated that nitric oxide synthase (NOS) is the key molecule for S-nitrosylation of ryanodine receptor 1 (RyR1) in DMD model mice (mdx mice) and that both neuronal NOS (nNOS) and inducible NOS (iNOS) might contribute to the
Ken’ichiro Nogami +7 more
doaj +1 more source