Results 31 to 40 of about 15,708 (115)
PLoS ONE, 2016 S-nitrosylation of several Ca2+ regulating proteins in response to β-adrenergic stimulation was recently described in the heart; however the specific nitric oxide synthase (NOS) isoform and signaling pathways responsible for this modification have not ...
Alejandra Z Vielma +4 more
doaj +1 more source
Advanced Science, EarlyView.A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li +13 more
wiley +1 more source
Arsenic Modulates Posttranslational S-Nitrosylation and Translational Proteome in Keratinocytes
The Scientific World Journal, 2014 Arsenic is a class I human carcinogen (such as inducing skin cancer) by its prominent chemical interaction with protein thio (-SH) group. Therefore, arsenic may compromise protein S-nitrosylation by competing the -SH binding activity.
Bin Huang +5 more
doaj +1 more source
Suppression of VEGFD expression by S-nitrosylation promotes the development of lung adenocarcinoma
Journal of Experimental & Clinical Cancer Research, 2022 Background Vascular endothelial growth factor D (VEGFD), a member of the VEGF family, is implicated in angiogenesis and lymphangiogenesis, and is deemed to be expressed at a low level in cancers.
Qiangqiang He +9 more
doaj +1 more source
RecSNO: Prediction of Protein S-Nitrosylation Sites Using a Recurrent Neural Network
IEEE Access, 2021 S-Nitrosylation modification is one of the most important post-translational modifications; it plays a critical role in a vast variety of biological processes and is related to various diseases.
Arslan Siraj +3 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.We report a cellular membrane‐targeted europium(III) probe, Eu.Chol, that enables selective, time‐resolved detection of peroxynitrite (ONOO−) at the cell membrane interface. Eu.Chol demonstrates efficient incorporation into liposomes and Jurkat cells, with minimal response to H2O2, establishing a modular platform for subcellular ONOO− sensing ...
Jamie Webb +6 more
wiley +1 more source
Redox BiologyNitric oxide (NO) influences a multitude of physiological and pathological processes. A major part of NO signaling involves S-nitrosylation (SNO), a post-translational modification in which an NO moiety is added to a selective cysteine thiol of a protein
Mélina Meunier +2 more
doaj +1 more source
GPS-SNO: computational prediction of protein S-nitrosylation sites with a modified GPS algorithm.
PLoS ONE, 2010 As one of the most important and ubiquitous post-translational modifications (PTMs) of proteins, S-nitrosylation plays important roles in a variety of biological processes, including the regulation of cellular dynamics and plasticity. Identification of S-
Yu Xue +6 more
doaj +1 more source
Hypothalamic S-nitrosylation contributes to the counter-regulatory response impairment following recurrent hypoglycemia. [PDF]
PLoS ONE, 2013 Hypoglycemia is a severe side effect of intensive insulin therapy. Recurrent hypoglycemia (RH) impairs the counter-regulatory response (CRR) which restores euglycemia.
Xavier Fioramonti +11 more
doaj +1 more source
Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security
Journal of the Science of Food and Agriculture, EarlyView.Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori +9 more
wiley +1 more source