Results 161 to 170 of about 37,527 (267)

In vitro Detection of S-acylation on Recombinant Proteins via the Biotin-Switch Technique [PDF]

, 2014
Qi Dong, Roger W. Innes
openalex   +1 more source

University teaching of mass spectrometry as a key practical technique within the context of a fully integrated, spiral curriculum

Rapid Communications in Mass Spectrometry, EarlyView.
Rationale Mass spectrometry (MS) is introduced to high school students in the UK in many pre‐university course syllabi. As such, we have identified the use of MS as a key technique that should be taught practically to undergraduates from the outset of their studies.
Andrew F. Worrall, Craig D. Campbell, Megan O. Midson, Malcolm I. Stewart   +3 more
wiley   +1 more source

S-acylation of p62 promotes p62 droplet recruitment into autophagosomes in mammalian autophagy. [PDF]

Mol Cell, 2023
Huang X, Yao J, Liu L, Chen J, Mei L, Huangfu J, Luo D, Wang X, Lin C, Chen X, Yang Y, Ouyang S, Wei F, Wang Z, Zhang S, Xiang T, Neculai D, Sun Q, Kong E, Tate EW, Yang A.   +20 more
europepmc   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Reduced S-acylation of SQSTM1/p62 in Huntington disease is associated with impaired autophagy [PDF]

, 2023
Fatima Abrar, Martyn C. Davies, Ashish Kumar, Alexis Dang, Yvonne Nguyen, Jennifer A. Collins, Nicholas S. Caron, J.S. Choudhary, Shaun S. Sanders, Mark O. Collins, Michael R. Hayden, Dale D. O. Martin   +11 more
openalex   +1 more source

A new sulfoxide analog of 1,2,3,6-tetrahydrophenylpyridine and antimicrobial activity [PDF]

, 2010
Bioactivities of thiotetrahydropyridines were previously described. Herein, a novel bioactive sulfoxide analog; N-acetyl-2-(1-adamantylsulfoxo)-3-acetoxy-4-phenyl-6-hydroxy-1,2,3,6-tetrahydropyridine (3) from the deoxydative substitution of 4 ...
Pingaew, Ratchanok, Prachayasittikul, Supaluk, Prachayasittikul, Virapong, Ruchirawat, Somsak, Worachartcheewan, Apilak   +4 more
core  

Illicit Drug‐Derived Volatile Organic Compounds as Markers for Application in Noncontact Detection Technology

The Chemical Record, EarlyView.
This review highlights the characteristic odor markers of illicit drugs, emphasizing volatile markers from both natural and synthetic sources, and explores the shift from canine‐based detection to emerging noncontact sensing technologies. Illicit drug use remains a global concern, requiring effective detection methods to counter evolving concealment ...
Minwoo Kim, Solpa Lee, Anmo J. Kim, Cong Wang, Yongwoo Jang   +4 more
wiley   +1 more source

Novel chiral precursors of 6-s-cis locked 1α,25-dihydroxyvitamin D3 analogues through selective enzymatic acylation

, 2002
M.R. Díaz, Miguel Ferrero, Susana Fernández, Vicente Gotor   +3 more
openalex   +2 more sources

CATALYTIC ASYMMETRIC ACYLATION OF ALCOHOLS USING A CHIRAL 1,2-DIAMINE DERIVED FROM (S)-PROLINE: (1S,2S)-trans-1-BENZOYLOXY-2-BROMOCYCLOHEXANE [PDF]

, 2006

openalex   +1 more source

Benzochromanone and Benzochromene Natural Products: Synthetic Strategies and Total Syntheses

The Chemical Record, EarlyView.
This work outlines synthetic strategies for natural products with benzochromanone and benzochromene cores. Key achievements include total syntheses of xanthones, blennolide C, gonytolide C, and teretifolione B. Spirochromanone intermediates, benzyne–furan Diels–Alder reactions, and enzymatic resolution enabled efficient and enantioselective access to ...
Takuya Kumamoto
wiley   +1 more source