Results 91 to 100 of about 25,478 (242)
Biotechnology for Biofuels, 2019 Background S-Adenosylmethionine (SAM) is a critical cofactor involved in many biochemical reactions. However, the low fermentation titer of SAM in methionine-free medium hampers commercial-scale production.
Liying Ruan +7 more
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Methionine adenosyltransferase (s-adenosylmethionine synthetase).
Advances in enzymology and related areas of molecular biology, 2011 El pdf es la versión post-print.
Pajares, María A., Markham, George D.
openaire +4 more sources
iMetaOmics, EarlyView.We generated the first comprehensive view of RNA viral auxiliary metabolic genes (AMGs), expanding the known functional type of AMGs by 75%. RNA viruses encode a remarkably high diversity of AMGs, spanning 25 distinct functional categories. Most of these genes are linked to environmental regulation and genetic information processing, with fewer ...
Yang Zhao +4 more
wiley +1 more source
Fresh Insights Into SLC25A26: Potential New Therapeutic Target for Cancers: A Review
Oncology ReviewsSLC25A26 is the only known human mitochondrial S-adenosylmethionine carrier encoding gene. Recent studies have shown that SLC25A26 is abnormally expressed in some cancers, such as cervical cancer, low-grade glioma, non-small cell lung cancer, and liver ...
Yangheng Xu +7 more
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Brazilian Journal of Medical and Biological Research, 2014 DNA hypomethylation may activate oncogene transcription, thus promoting carcinogenesis and tumor development. S-adenosylmethionine (SAM) is a methyl donor in numerous methylation reactions and acts as an inhibitor of intracellular demethylase activity ...
M.X. Da, Y.B. Zhang, J.B. Yao, Y.X. Duan
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Recognition ofS‐adenosylmethionine by riboswitches [PDF]
WIREs RNA, 2011 AbstractRiboswitches are regulatory elements commonly found in the 5′ leader sequences of bacterial mRNAs that bind cellular metabolites to direct expression at either the transcriptional or translational level. The effectors of these RNAs are chemically diverse, including nucleobases and nucleosides, amino acids, cofactors, and second messenger ...
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iMetaOmics, EarlyView.This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu +8 more
wiley +1 more source
Algorithm of management of patient with alcohol-induced liver disease
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2011 The aim of review. To present main pathogenic aspects of development of alcohol-induced liver disease (ALD), principles of diagnostics and treatment of this disease.Original positions.
M. V. Mayevskaya, M. A. Morozova
doaj
Engineered reduction of S-adenosylmethionine alters lignin in sorghum
Biotechnology for Biofuels and BioproductsBackground Lignin is an aromatic polymer deposited in secondary cell walls of higher plants to provide strength, rigidity, and hydrophobicity to vascular tissues.
Yang Tian +25 more
doaj +1 more source
Targeting SHMT2‐mediated membrane phospholipid remodeling for enhanced anti‐GCSCs treatment
Interdisciplinary Medicine, EarlyView.Depletion of serine via serine hydroxymethyltransferase‐2 (SHMT2) knockdown in gastric cancer (GC) disrupted the maintenance of gastric cancer stem cell stemness by inducing membrane phospholipid remodeling and aberrant CD44 shedding within membrane lipid rafts. The synthesized HA‐Exo‐si SHMT2 demonstrated enhanced therapeutic efficacy and safety in GC.
Liping Yang +10 more
wiley +1 more source