Results 101 to 110 of about 60,031 (297)

S-Adenosylmethionine May Mitigate Obstructive Sleep Apnea in an Adult with Down Syndrome: A Case Report

open access: yesNature and Science of Sleep, 2022
Silvano Dragonieri,1 Giovanna Elisiana Carpagnano,1 Salvatore Caccamese2 1Department of Respiratory Diseases, University of Bari, Bari, Italy; 2Department of Chemical Sciences, University of Catania, Catania, ItalyCorrespondence: Silvano ...
Dragonieri S, Carpagnano GE, Caccamese S
doaj  

Chronic hepatitis in horses with persistent equine hepacivirus infection

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Equine hepacivirus (EqHV) is closely related to hepatitis C virus (HCV), which causes persistent infection and chronic hepatitis in people. Information on persistent EqHV infection and hepatitis is limited. Objectives To report 19 cases of chronic hepatitis and persistent EqHV infection.
Mason C. Jager   +13 more
wiley   +1 more source

Methylation of the Gpat2 promoter regulates transient expression during mouse spermatogenesis [PDF]

open access: yes, 2015
Spermatogenesis is a highly regulated process that involves both mitotic and meiotic divisions, as well as cellular differentiation to yield mature spermatozoa from undifferentiated germinal stem cells.
Cattaneo, Elizabeth Renee   +6 more
core   +2 more sources

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

open access: yesThe FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova   +5 more
wiley   +1 more source

Environment, epigenetics and neurodegeneration: Focus on nutrition in Alzheimer's disease [PDF]

open access: yes, 2015
Many different environmental factors (nutrients, pollutants, chemicals, physical activity, lifestyle, physical and mental stress) can modulate epigenetic markers in the developing and adult organism. Epigenetics, in turn, can cause and is associated with
FUSO, ANDREA   +2 more
core   +3 more sources

Discrete and cell‐specific hypoxic responses in Arabidopsis roots resolved by single‐nuclei transcriptomics

open access: yesNew Phytologist, EarlyView.
Summary With the intensification of unpredictable flooding events because of global warming, there is a need to understand how root cells perceive and respond to oxygen deprivation. The use of high‐throughput single‐nuclei RNA‐sequencing (snRNA‐Seq) allows the examination of gene expression profiles in discrete cell types.
Robert D. Hill   +5 more
wiley   +1 more source

Methotrexate-associated biochemical alterations in a patient with chronic neurotoxicity [PDF]

open access: yesJournal of Medical Biochemistry, 2009
Intrathecal and/or high-dose intravenous administration of methotrexate (MTX) in the treatment of malignancies such as acute lymphoblastic leukaemia (ALL) has been associated with cases of mild to severe neurotoxicity.
Vezmar Sandra, Bode Udo, Jaehde Ulrich
doaj  

Maternal Obesity and MicroRNAs in Breast Milk: Implications for Infant Developmental Programming

open access: yesObesity Reviews, EarlyView.
ABSTRACT This review explores the relationship between maternal obesity and alterations in the expression of microRNAs (miRNAs) in breast milk, highlighting how these changes may influence the developmental programming of the infant. Evidence suggests that maternal obesity can affect the bioactive composition of breast milk, including miRNA profiles ...
Gyslane M. Santos   +2 more
wiley   +1 more source

Expression of a constitutively active nitrate reductase increases SARS‐CoV‐2 Spike protein production in Nicotiana benthamiana leaves that otherwise show traits of senescence

open access: yesPlant Biotechnology Journal, EarlyView.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the Spike (S) protein of Severe Acute Respiratory Syndrome Coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana, a process promoted by the co‐expression of viral silencing suppressor P19.
Louis‐Philippe Hamel   +9 more
wiley   +1 more source

Root protein interatomic network obtained from citrus seedlings subjected to water deficit : S08O03 [PDF]

open access: yes, 2012
Citrus Brazilian industry may be strongly affected by drought. Characterize rootstock behavior under different environmental conditions is crucial, since rootstocks may confer better adaption to environmental stresses.
Bonatto, Diego   +7 more
core  

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