Results 111 to 120 of about 25,478 (242)

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Coupling S-adenosylmethionine-dependent methylation to growth: Design and uses.

open access: yesPLoS Biology, 2019
We present a selection design that couples S-adenosylmethionine-dependent methylation to growth. We demonstrate its use in improving the enzyme activities of not only N-type and O-type methyltransferases by 2-fold but also an acetyltransferase of another
Hao Luo   +13 more
doaj   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

Thermochemical Recycling and Degradation Strategies of Halogenated Polymers (F−, Cl−, Br−): A Holistic Review Coupled with Mechanistic Insights

open access: yesThe Chemical Record, EarlyView.
This review aims to comprehensively address recent degradation techniques (physical, chemical and biological) of halogenated waste polymers with a prime focus on thermal degradation techniques. Exploiting various metal oxides during co‐pyrolysis is deemed a viable solution for recycling halogenated polymeric waste.
Mohamed Shafi Kuttiyathil   +2 more
wiley   +1 more source

Investigations into Uncharacterized Radical S-adenosylmethionine Enzymes [PDF]

open access: yes, 2015
Radical S-adenosylmethionine (SAM) enzymes are a superfamily of enzymes that require the cofactor SAM for catalysis. These enzymes have diverse functions across all 3 domains of life, and are known to play roles in many biological pathways, including ...
Quintanilla, Melissa
core   +1 more source

(S)–S-adenosylmethionine in the treatment of pre-menstrual disorders in adult women: A protocol for an open-label pilot study

open access: yesContemporary Clinical Trials Communications
Pre-menstrual disorders, including pre-menstrual syndrome and pre-menstrual dysphoric disorder, are highly prevalent disorders in women of reproductive age. Pre-menstrual disorders are associated with debilitating symptoms that onset in the days prior to
Brendan Stevenson   +3 more
doaj  

Salvage of the 5-deoxyribose byproduct of radical SAM enzymes

open access: yesNature Communications, 2018
5-Deoxyribose is formed from 5′-deoxyadenosine, a toxic byproduct of radical S-adenosylmethionine enzymes. Here, the authors identify and biochemically characterize a bacterial salvage pathway for 5-deoxyribose, consisting of three enzymes, and solve the
Guillaume A. W. Beaudoin   +7 more
doaj   +1 more source

Regulation of S -Adenosylmethionine Synthetase in Escherichia coli [PDF]

open access: bronze, 1970
Caroline T. Holloway   +2 more
openalex   +1 more source

Extrahepatic biliary obstruction secondary to a peritoneopericardial diaphragmatic hernia in a dog

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract A 16‐month‐old, entire, male dobermann presented for evaluation of emesis, anorexia and lethargy. Upon examination, the dog was found to be severely icteric. Serum biochemistry revealed an elevated total bilirubin and alkaline phosphatase, and computed tomographic imaging revealed a peritoneopericardial diaphragmatic hernia with abdominal ...
Emily Durocher   +3 more
wiley   +1 more source

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