Results 61 to 70 of about 25,478 (242)

EFFECT OF S-ADENOSYLMETHIONINE ON HEPATIC AND METABOLIC DISORDERS IN GUINEA PIGS WITH NONALCOHOLIC STEATOHEPATITIS

İstanbul Tıp Fakültesi Dergisi
Objective: S-adenosylmethionine (SAM) has antioxidant and anti-inflammatory actions and hepatoprotective potential. In this study, the therapeutic effectiveness of SAM was investigated in high-fat/cholesterol diet (HFCD)-induced non-alcoholic ...
İlknur Bingül, Canan Küçükgergin, Abdurrahman Fatih Aydın, Aydın Çevik, Merva Soluk Tekkeşin, Necat Vakur Olgaç, Semra Doğru Abbasoğlu, Mehmet Müjdat Uysal   +7 more
doaj   +1 more source

S-Adenosylmethionine (SAMe) in major depressive disorder (MDD): a clinician-oriented systematic review

Annals of General Psychiatry, 2020
Background Major depressive disorder (MDD) is a recurrent illness with high rates of chronicity, treatment-resistance, and significant economic impact.
Alessandro Cuomo, Bruno Beccarini Crescenzi, Simone Bolognesi, Arianna Goracci, Despoina Koukouna, Rodolfo Rossi, Andrea Fagiolini   +6 more
doaj   +1 more source

Phytohormonal regulation of S‐adenosylmethionine synthetase and S‐adenosylmethionine levels in dwarf pea epicotyls

FEBS Letters, 1991
A significant stimulation (2‐ to 2.5‐fold) of AdoMet synthetase was witnessed in glibberellicd acid (GA3, 1μM)‐treated epicotyls of the dwarf pea (Pisum sativum). This was accompanied by a 2.4‐fold increase in the endogenous pool of S‐adenosylmethionine. Both abscisic acid (10 μM) and cycloheximide (20 ) inhibited the GA3‐mediated enhancement of AdoMet
Mukul Mathur, R.C. Sachar
openaire   +3 more sources

Methionine adenosyltransferase II beta subunit gene expression provides a proliferative advantage in human hepatoma [PDF]

, 2003
BACKGROUND & AIMS: Of the 2 genes (MAT1A, MAT2A) encoding methionine adenosyltransferase, the enzyme that synthesizes S-adenosylmethionine, MAT1A, is expressed in liver, whereas MAT2A is expressed in extrahepatic tissues.
Avila, M.A. (Matías Antonio), Caballeria, J. (Juan), Fortes, P. (Puri), Latasa, M.U. (María Ujué), Martin-Duce, A. (Antonio), Martinez-Chantar, M.L. (María Luz), Mato, J.M. (José María), Ruiz Garcia-Trevijano, E. (Elena)   +7 more
core  

Non-alcoholic fatty liver disease and cognitive impairment [PDF]

Терапевтический архив
Aim. To evaluate the efficacy of oral administration of the original ademetionine (Geptral) at a dose of 1500 mg/s in patients with NAFLD at the steatosis stage and cognitive impairment within the framework of a prospective observational open non ...
Elena V. Onuchina, Bairma B. Dambaeva, Anna G. Glazunova, Ayuna Kh. Mikhailova, Elena M. Vorobyova, Elena I. Soshina, Natalya V. Efremenko   +6 more
doaj   +1 more source

Structure and regulation of mammalian S-adenosylmethionine decarboxylase [PDF]

, 1988
In order to understand the structure and regulation of S-adenosylmethionine decarboxylase, cDNA clones encoding this enzyme have been isolated from rat prostate and human fibroblast cDNA libraries.
Crozat, A., Ihalainen, R., Janne, O. A., Laitinen, P. H., Madhubala, R., Pajunen, A., Pegg, A. E., Stanley, B.   +7 more
core  

Mathematical modelling of polyamine metabolism in bloodstream-form trypanosoma brucei: An application to drug target identification [PDF]

, 2013
© 2013 Gu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
AE Pegg, AH Fairlamb, AJ Bitonti, AJ Bitonti, Andrew R. Dalby, B Goldberg, BJ Berger, C Rodriguez-Caso, CJ Bacchi, CJ Bacchi, CJ Bacchi, CJ Bacchi, CW Porter, David Gilbert, David Reid, Desmond J. Higham, ED Sontag, EK Willert, EK Willert, F Checchi, G Priotto, H Kitano, IM Vincent, JF Turrens, JR Sufrin, JR Sufrin, K Kaur, L Birnbaumer, L Christa, L Ljung, LY Ghoda, M Duszenko, MC Taylor, MK Riscoe, MR Ariyanayagam, MR Ariyanayagam, N Yarlett, N Yarlett, N Yarlett, NAW van Riel, NAW van Riel, O Erez, O Heby, PK Fyfe, RM Reguera, S Muller, S Peter, SL Oza, SL Oza, T Suzuki, TC Beswick, V Bellofatto, V Olin-Sandoval, Xu Gu, Y Xiao   +54 more
core   +9 more sources

UTILIZATION OF S-ADENOSYLMETHIONINE BY MICROORGANISMS [PDF]

Journal of Bacteriology, 1962
Shapiro, Stanley K. (Argonne National Laboratory, Argonne, Ill.). Utilization of S-adenosylmethionine by microorganisms. J. Bacteriol. 83: 169–174. 1962.—Two types of mutants of Aerobacter aerogenes that utilize S-adenosylmethionine for growth are described. One type also responds
openaire   +3 more sources

A new spin on chemotaxonomy: Using non‐proteogenic amino acids as a test case

Applications in Plant Sciences, EarlyView.
Abstract Premise Specialized metabolites serve various roles for plants and humans. Unlike core metabolites, specialized metabolites are restricted to certain plant lineages; thus, in addition to their ecological functions, specialized metabolites can serve as diagnostic markers of plant lineages.
Makenzie Gibson, William Thives Santos, Alan R. Oyler, Lucas Busta, Craig A. Schenck   +4 more
wiley   +1 more source

Methionine adenosyltransferases in liver cancer. [PDF]

, 2019
Methionine adenosyltransferases (MATs) are essential enzymes for life as they produce S-adenosylmethionine (SAMe), the biological methyl donor required for a plethora of reactions within the cell.
Barbier-Torres, Lucia, Fan, Wei, Lu, Shelly C, Mato, José M, Murray, Ben   +4 more
core