Results 81 to 90 of about 60,031 (297)
Metformin use in pregnancy: promises and uncertainties [PDF]
, 2017 Metformin has been prescribed in pregnancy for over 40 years; for much of this time, use has been limited both in numbers and geographically, and the evidence base has been confined to observational studies.
Lindsay, Robert S., Loeken, Mary R.
core +1 more source
FEBS Letters, 1991 A significant stimulation (2‐ to 2.5‐fold) of AdoMet synthetase was witnessed in glibberellicd acid (GA3, 1μM)‐treated epicotyls of the dwarf pea (Pisum sativum). This was accompanied by a 2.4‐fold increase in the endogenous pool of S‐adenosylmethionine. Both abscisic acid (10 μM) and cycloheximide (20 ) inhibited the GA3‐mediated enhancement of AdoMet
Mathur, Mukul, Sachar, R.C.
openaire +2 more sources
How tissue damage MET metabolism: Regulation of the systemic damage response
Fly, 2017 Living organisms experience tissue damage from both, the surrounding environment and from inside their bodies. Tissue repair/regeneration is triggered by local tissue injury to restore an injured, or lost, part of the body.
Soshiro Kashio +2 more
doaj +1 more source
An Orthogonal Way of Writing the Tubulin Code
Cytoskeleton, EarlyView.ABSTRACT The Elongator complex has long been characterized for its role in tRNA modification and modulation of protein translation. Beyond these established functions, recent findings reveal an unexpected role for Elongator in directly interacting and tuning microtubule dynamics and properties, broadening its biological significance in eukaryotic cells.
Vicente Jose Planelles‐Herrero +1 more
wiley +1 more source
Non-alcoholic fatty liver disease and cognitive impairment [PDF]
Терапевтический архивAim. To evaluate the efficacy of oral administration of the original ademetionine (Geptral) at a dose of 1500 mg/s in patients with NAFLD at the steatosis stage and cognitive impairment within the framework of a prospective observational open non ...
Elena V. Onuchina +6 more
doaj +1 more source
Methionine adenosyltransferases in liver cancer. [PDF]
, 2019 Methionine adenosyltransferases (MATs) are essential enzymes for life as they produce S-adenosylmethionine (SAMe), the biological methyl donor required for a plethora of reactions within the cell.
Barbier-Torres, Lucia +4 more
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Redox-based epigenetic status in drug addiction: a potential contributor to gene priming and a mechanistic rationale for metabolic intervention [PDF]
, 2015 Alcohol and other drugs of abuse, including psychostimulants and opioids, can induce epigenetic changes: a contributing factor for drug addiction, tolerance and associated withdrawal symptoms.
Malav S. Trivedi, Richard Deth
core +3 more sources
Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy +7 more
wiley +1 more source
Draft Genome Sequence for Desulfovibrio africanus Strain PCS. [PDF]
, 2013 Desulfovibrio africanus strain PCS is an anaerobic sulfate-reducing bacterium (SRB) isolated from sediment from Paleta Creek, San Diego, CA. Strain PCS is capable of reducing metals such as Fe(III) and Cr(VI), has a cell cycle, and is predicted to ...
Arkin, Adam P +6 more
core +2 more sources
Biotechnology for Biofuels, 2019 Background S-Adenosylmethionine (SAM) is a critical cofactor involved in many biochemical reactions. However, the low fermentation titer of SAM in methionine-free medium hampers commercial-scale production.
Liying Ruan +7 more
doaj +1 more source