Results 11 to 20 of about 15,774 (176)
Metabolic modulation of TCA cycle by S-nitrosylation in Monascus spp. [PDF]
Synthetic and Systems BiotechnologyMonascus spp. produces several beneficial secondary metabolites (SMs), such as Monacolin K and Monascus pigments, which have wide applications in the pharmaceutical and food industries.
Zitong Meng +3 more
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Nature Communications, 2023 Reversible protein S-nitrosylation regulates a wide range of biological functions and physiological activities in plants. However, it is challenging to quantitively determine the S-nitrosylation targets and dynamics in vivo.
Guochen Qin +7 more
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S‐nitrosylation of cytoskeletal proteins [PDF]
Cytoskeleton, 2019 AbstractNitric oxide has pronounced effects on cellular functions normally associated with the cytoskeleton, including cell motility, shape, contraction, and mitosis. Protein S‐nitrosylation, the covalent addition of a NO group to a cysteine sulfur, is a signaling pathway for nitric oxide that acts in parallel to cyclic guanosine monophosphate (cGMP ...
Allison L. Horenberg +4 more
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Computational prediction of candidate proteins for S-nitrosylation in Arabidopsis thaliana. [PDF]
PLoS ONE, 2014 Nitric oxide (NO) is an important signaling molecule that regulates many physiological processes in plants. One of the most important regulatory mechanisms of NO is S-nitrosylation-the covalent attachment of NO to cysteine residues.
Mounira Chaki +3 more
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Signaling by S-nitrosylation in the heart [PDF]
Journal of Molecular and Cellular Cardiology, 2014 Nitric oxide is a gaseous signaling molecule that is well-known for the Nobel prize-winning research that defined nitric oxide as a physiological regulator of blood pressure in the cardiovascular system. Nitric oxide can signal via the classical pathway involving activation of guanylyl cyclase or by a post-translational modification, referred to as S ...
Elizabeth, Murphy +6 more
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Nitrosothiol-Trapping-Based Proteomic Analysis of S-Nitrosylation in Human Lung Carcinoma Cells. [PDF]
PLoS ONE, 2017 Nitrosylation of cysteines residues (S-nitrosylation) mediates many of the cellular effects of nitric oxide in normal and diseased cells. Recent research indicates that S-nitrosylation of certain proteins could play a role in tumor progression and ...
Shani Ben-Lulu +3 more
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Regulation of Ras Signaling by S-Nitrosylation
Antioxidants, 2023 Ras are a family of small GTPases that function as signal transduction mediators and are involved in cell proliferation, migration, differentiation and survival. The significance of Ras is further evidenced by the fact that Ras genes are among the most mutated oncogenes in different types of cancers.
Sónia Simão +3 more
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Proteomic identification of S-nitrosylated Golgi proteins: new insights into endothelial cell regulation by eNOS-derived NO. [PDF]
PLoS ONE, 2012 Endothelial nitric oxide synthase (eNOS) is primarily localized on the Golgi apparatus and plasma membrane caveolae in endothelial cells. Previously, we demonstrated that protein S-nitrosylation occurs preferentially where eNOS is localized.
Panjamaporn Sangwung +5 more
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GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation
Cell Reports, 2023 Summary: Nitric oxide (NO) production in the tumor microenvironment is a common element in cancer. S-nitrosylation, the post-translational modification of cysteines by NO, is emerging as a key transduction mechanism sustaining tumorigenesis.
Salvatore Rizza +17 more
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S-Nitrosylation of mitochondrial caspases [PDF]
The Journal of Cell Biology, 2001 Caspase-3 is a cysteine protease located in both the cytoplasm and mitochondrial intermembrane space that is a central effector of many apoptotic pathways. In resting cells, a subset of caspase-3 zymogens is S-nitrosylated at the active site cysteine, inhibiting enzyme activity.
Mannick, Joan B. +6 more
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