Results 51 to 60 of about 21,088,255 (155)

PENGARUH PENGERING AEROSIL DAN KROSPOVIDON TERHADAP KARAKTERISTIK FISIK SOLID-SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM KURKUMIN

JIIS: Jurnal Ilmiah Ibnu Sina
Kurkumin termasuk dalam BCS II dengan kelarutan rendah namun permeabilitas tinggi. Pada penelitian sebelumnya telah diperoleh SNEDDS kurkumin dengan komposisi kurkumin 7 mg/mL, VCO (11%), tween 80 (65,66%) dan PEG 400 (23,34%), namun sediaan tersebut ...
Iis Wahyuningsih, Muhammad Rhapis Kyllingga   +1 more
doaj   +1 more source

Enhanced Anti-Inflammatory Activity of Kaempferia galanga Extract by Solid Self-Nanoemulsifying Drug Delivery System and Its Development in Fast Disintegrating Tablet

Science and Technology Indonesia
The increasing global incidence of osteoarthritis (OA) emphasizes the need for effective treatments, particularly for the elderly. Conventional OA treatments pose administration challenges, leading to patient discomfort due to difficulties in ...
Salma Latifani, Annisa nur Fitriani, Paniroy, Kadek Sanitha Maesayani, Juan Freddy, Oktavia Rahayu Adianingsih   +5 more
doaj   +1 more source

Hemp Proteins Conjugated with Green Tea Polyphenol Extract Form De Novo Plant‐Sourced Emulsifiers Suitable for Nanodelivery Systems Bearing Lipophilic Psychopharmaceuticals

Advanced Therapeutics, Volume 8, Issue 11, November 2025.
Green tea polyphenols, conjugated either covalently or non‐covalently to hemp protein, comprise an excellent stabilizing matrix for oxidatively‐sensitive small molecules. These nanoemulsions are highly stable to a variety of chemical and physical stressors, protecting the small molecule while allowing for easy uptake across cell membranes and rapid ...
William Charles Hosie, Abhinandan Banerjee, Mary Augustina Egbuta, Kasra Razmkhah, Behzad Bolandi, Khalilalrahman Dehvari, Anton Homon, Aleena Kappadakunnel, Jonathan J. Simone, John F. Trant   +9 more
wiley   +1 more source

Kajian Pengembangan Sediaan Self Nanoemulsifying Drug Delivery System (SNEDDS) untuk Penghantaran Agen Antidiabetik Oral

, 2021
Diabetes melitus (DM) adalah penyakit metabolik akibat gangguan aktivitas atau sekresi insulin, dengan angka kejadian dan morbiditas yang terus meningkat.
Priani, Sani Ega, Priani, S. E. (Sani)
core   +1 more source

Quality by design aided self-nano emulsifying drug delivery systems development for the oral delivery of Benidipine: Improvement of biopharmaceutical performance

Drug Delivery
The primary objective of the research effort is to establish efficient solid self-nanoemulsifying drug delivery systems (S-SNEDDS) for benidipine (BD) through the systematic application of a quality-by-design (QbD)-based paradigm.
Sheetal S. Buddhadev, Kevinkumar C. Garala, Saisivam S, Mohamed Rahamathulla, Mohammed Muqtader Ahmed, Syeda Ayesha Farhana, Ismail Pasha   +6 more
doaj   +1 more source

A Hyaluronic Acid Functionalized Self-Nano-Emulsifying Drug Delivery System (SNEDDS) for Enhancement in Ciprofloxacin Targeted Delivery against Intracellular Infection [PDF]

, 2021
Ciprofloxacin (CIP), a potent anti-bacterial agent of the fluroquinolone family, shows poor solubility and permeability, thus leading to the development of intracellular pathogens induced multi-drug resistance and biofilms formation.
Shahnaz, G, Rahdar, A, Ibrahim, IM, Kiani, MH, Pandey, S, Arshad, R, Kang, M, Tabish, TA   +7 more
core   +1 more source

Influence of Solid Drug Delivery System Formulation on Poorly Water-Soluble Drug Dissolution and Permeability

Molecules, 2015
The majority of drugs have a low dissolution rate, which is a limiting step for their absorption. In this manuscript, solid dispersions (SD), solid self-microemulsifying drug delivery systems (S-SMEDDS) and solid self-nanoemulsifying drug delivery ...
Marko Krstić, Miljana Popović, Vladimir Dobričić, Svetlana Ibrić   +3 more
doaj   +1 more source

Innovative Self Nano‐Emulsifying Drug Delivery Systems for Peptic Ulcer Therapy: A Review

Particle &Particle Systems Characterization, Volume 42, Issue 1, January 2025.
SNEDDS improve bioavailability and solubility of poorly water‐soluble drugs, aiding in peptic ulcer treatment and regenerative healing. This innovative drug delivery bypasses side effects of conventional forms, utilizing biocompatible macromolecules to enhance solubility and promote healing. SNEDDS‐based systems show promise in boosting drug solubility
Syed Hassan Mujtaba, Rabia Arshad, Waqar Aman, Kashif Barkat, Abdul Malik, Anam Fatima, Salman Arshad Khan, Haleema Sadia, Gul e Maryam, Zeinab Moafian, Abbas Rahdar, M. Ali Aboudzadeh   +11 more
wiley   +1 more source

QbD‐Based Development of Self‐Nanoemulsifying Drug Delivery System for Codelivery of Simvastatin and Ezetimibe With Enhanced In Vitro Dissolution

Journal of Nanotechnology, Volume 2025, Issue 1, 2025.
Simvastatin and ezetimibe are antihyperlipidemic agents that exhibit synergistic therapeutic effects but have poor aqueous solubility, resulting in low and variable oral bioavailability. This study aimed to develop an optimized self‐nanoemulsifying drug delivery system (SNEDDS) for the codelivery of simvastatin and ezetimibe using a quality‐by‐design ...
Sani Ega Priani, Anis Yohana Chaerunisaa, Gofarana Wilar, Iyan Sopyan, Mozhgan Afshari   +4 more
wiley   +1 more source

Formulation and Characterization of Solid Self Nano Emulsifying Drug Delivery System (S-SNEDDS) Loading Curcuma xanthorrhiza Extract

Curcuma xanthorrhiza has an active component xanthorrhizol that is poorly soluble in water, resulting in limited absorption and bioavailability. Liquid Self Nano Emulsifying Drug Delivery System (SNEDDS) dosage formulations can improve its solubility and
Taher, Muhammad, Syukri, Yandi, Seran, Yuvina, Ramadhani, Arba Pramundita, Hannie Fitriani   +4 more
core   +1 more source