Results 61 to 70 of about 21,088,255 (155)

Solid Self-Nanoemulsifying Drug Delivery Systems of Furosemide: In Vivo Proof of Concept for Enhanced Predictable Therapeutic Response

Pharmaceuticals
Liquid self-nano emulsifying drug delivery systems (SNEDDS) of furosemide (FSM) have been explored as a potential solution for enhancing solubility and permeability but are associated with rapid emulsification, spontaneous drug release, and poor in vivo ...
Sania Gul, Sathvik Belagodu Sridhar, Aamir Jalil, Muhammad Akhlaq, Muhammad Sohail Arshad, Hafiz Shoaib Sarwar, Faisal Usman, Javedh Shareef, Sabin Thomas   +8 more
doaj   +1 more source

Multitarget Anti‐Candida Activity of Thai Plant Extracts and Essential Oils: Inhibiting Biofilm Formation, Denture Adhesion, and Germ Tube Formation

Scientifica, Volume 2025, Issue 1, 2025.
This study aimed to evaluate the efficacy of Thai plant extracts (PEs) and essential oils (EOs) against reference and clinical isolate strains of Candida albicans, focusing on their ability to inhibit biofilm formation, cell adhesion to denture acrylic, and germ tube formation. The minimum biofilm inhibition concentration (MBIC) and the minimum biofilm
Premnapa Sisopa, Supaporn Lamlertthon, Ruchadaporn Kaomongkolgit, Pratthana Chomchalao, Waree Tiyaboonchai, Simone Carradori   +5 more
wiley   +1 more source

Review: Characterisation and Dissolution of Low Solubility Active Substances in S-SNEDDS Preparations with Various Manufacturing Methods

JPSCR: Journal of Pharmaceutical Science and Clinical Research
SNEDDS is composed of a drug, surfactants, co-surfactants, and oils. Developing and optimising the correct formulation is necessary to minimise time and expense, and ensure the correct formulation.
Rodhia Ulfa, Husnun Khairunnisa’ Pratiwi   +1 more
doaj   +1 more source

Development and Evaluation of Simvastatin based Self nano emulsifying drug delivery system for treatment of Alzheimer’s Disease

Alzheimer's &Dementia, Volume 20, Issue S6, December 2024.
Abstract Background Alzheimer’s disease (AD) is one of the leading causes of mortality and morbidity across the globe. Its incidences are increasing at an immense rate due to inadequate patient compliance. Hence there is a requirement for a requisite treatment strategy.
Hardeep  , Narendra Kumar Pandey
wiley   +1 more source

Effects of chrysin loaded self‐nano emulsifying drug delivery system for the treatment of Alzheimer’s disease

Alzheimer's &Dementia, Volume 20, Issue S4, December 2024.
Abstract Background Alzheimer’s disease (AD) is a type of degenerative disorder that affects the brain. There are various herbal drugs that have been tested for their effectiveness in treating AD, and chrysin is one of them. Chrysin is a polyphenolic flavonoid that has several neuroprotective effects, including reducing the levels of AChE enzyme ...
Sukriti Vishwas, Sachin Kumar Singh, Monica Gulati, Kamal Dua, Violina Kakoty, Bushra Bashir   +5 more
wiley   +1 more source

Digital images of CN liquid SNEDDS at different storage conditions.

, 2018
(A) Freshly prepared liquid SNEDDS; (B) Liquid SNEDDS after a minimum of 6 months of accelerated storage conditions; (C) Liquid SNEDDS after a minimum of 6 months of intermediate storage conditions; (D) Liquid SNEDDS after a minimum of 12 months of long ...
Fars Kaed Alanazi (5537078), Ahmad Abdul-Wahhab Shahba (5537081), Sayed Ibrahim Abdel-Rahman (5537084)   +2 more
core   +1 more source

The Impact of Polymers on Enzalutamide Solid Self-Nanoemulsifying Drug Delivery System and Improved Bioavailability

Pharmaceutics
Enzalutamide (ENZ), marketed under the brand name Xtandi® as a soft capsule, is an androgen receptor signaling inhibitor drug actively used in clinical settings for treating prostate cancer. However, ENZ’s low solubility and bioavailability significantly
Su-Min Lee, Jeong-Gyun Lee, Tae-Han Yun, Chul-Ho Kim, Jung-Hyun Cho, Kyeong-Soo Kim   +5 more
doaj   +1 more source

Xanthohumol loaded self‐nano emulsifying drug delivery system: Harnessing neuroprotective effects in Alzheimer’s Disease management

Alzheimer's &Dementia, Volume 20, Issue S6, December 2024.
Abstract Background Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the impairment of cognitive development and disruption of neurocognitive function. This neuropathological condition is marked by neurodegeneration, loss of neural tissue, and the formation of neurofibrillary tangles and Aβ plaques. Various studies reported the
Bushra Bashir, Sachin Kumar Singh, Monica Gulati, Sukriti Vishwas, Kamal Dua   +4 more
wiley   +1 more source

Evaluating Various Lactose Types as Solid Carriers for Improving Curcumin Solubility in Solid Self-Nanoemulsifying Drug Delivery Systems (S-SNEDDSs) for Oral Administration

Sci
Curcumin, a bioactive compound derived from turmeric, possesses numerous pharmaceutical properties; however, its poor aqueous solubility and permeability result in low bioavailability. This study aims to develop a solid self-nanoemulsifying drug delivery
Panida Teerapipattanapong, Pimrada Jaikon, Nichapa Ningsanonda, Etsuo Yonemochi, Takayuki Furuishi, Namon Hirun, Pakorn Kraisit   +6 more
doaj   +1 more source

A Comprehensive Review of Solid Self Nano Emulsifying Drug Delivery System (S-SNEDDS) Technology to Enhance Nanoemulsion Stability [PDF]

Patients and practitioners prefer oral medication administration for systemic or local treatment due to its convenience and pleasurable experience. Nevertheless, numerous oral pharmaceutical formulations encounter various delivery challenges as a result ...
Yandi Syukri, Syafira Tri Nurmala Sari, Arba Pramundita Ramadani   +2 more
core   +1 more source