Results 1 to 10 of about 1,533,510 (152)

Multivariate Data Analysis and Central Composite Design-Oriented Optimization of Solid Carriers for Formulation of Curcumin-Loaded Solid SNEDDS: Dissolution and Bioavailability Assessment [PDF]

open access: yesPharmaceutics, 2022
The study was initiated with two major purposes: investigating the role of isomalt (GIQ9) as a pharmaceutical carrier for solid self-nanoemulsifying drug delivery systems (S-SNEDDSs) and improving the oral bioavailability of lipophilic curcumin (CUN ...
Bimlesh Kumar   +2 more
exaly   +6 more sources

Novel Solid Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) for Oral Delivery of Olmesartan Medoxomil: Design, Formulation, Pharmacokinetic and Bioavailability Evaluation

open access: yesPharmaceutics, 2016
The main purpose of this study was to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) of Olmesartan (OLM) for enhancement of its solubility and dissolution rate.
Ahmed Rifaat Mohamed Gardouh, Ali Nasr
exaly   +4 more sources

A Solid Ultra Fine Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) of Deferasirox for Improved Solubility: Optimization, Characterization, and In Vitro Cytotoxicity Studies

open access: yesPharmaceuticals, 2020
The research work was designed to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) of deferasirox (DFX). According to the solubility studies of DFX in different components, Peceol, Kolliphor EL, and Transcutol were selected as ...
Yıldız Özalp   +2 more
exaly   +4 more sources

In Vitro Evaluation of a Solid Supersaturated Self Nanoemulsifying Drug Delivery System (Super-SNEDDS) of Aprepitant for Enhanced Solubility

open access: yesPharmaceuticals, 2021
Aprepitant (APR) belongs to Class II of the Biopharmaceutical Classification System (BCS) because of its low aqueous solubility. The objective of the current work is to develop self-nanoemulsifying drug delivery systems (SNEDDS) of APR to enhance its ...
Håkan Nazli   +2 more
exaly   +4 more sources

Development of black cumin seed oil (Nigella sativa L.) SNEDDS into solid-SNEDDS and its characterization [PDF]

open access: yesPharmaciana, 2021
Black cumin seed oil (MBJH) (Nigella sativa L.) is a well-known herb with pharmacology activities such as anticancer and anti-thrombocytopenia. The limitation of MBJH has poor absorption when using oral dosage form.
Rodhia Ulfa, Dwi Utami, Iis Wahyuningsih
doaj   +3 more sources

Adsorbent Precoating by Lyophilization: A Novel Green Solvent Technique to Enhance Cinnarizine Release from Solid Self-Nanoemulsifying Drug Delivery Systems (S-SNEDDS)

open access: yesPharmaceutics, 2022
Background: Solidification by high surface area adsorbents has been associated with major obstacles in drug release. Accordingly, new approaches are highly demanded to solve these limitations.
Ahmad Yousef Tashish   +3 more
doaj   +2 more sources

Combined Curcumin and Lansoprazole-Loaded Bioactive Solid Self-Nanoemulsifying Drug Delivery Systems (Bio-SSNEDDS)

open access: yesPharmaceutics, 2021
Background: The current study aimed to design a novel combination of lansoprazole (LNS) and curcumin (CUR) solid oral dosage form using bioactive self-nanoemulsifying drug delivery systems (Bio-SSNEDDS).
Abdulrahman Alshadidi   +4 more
doaj   +2 more sources

Unlocking the Potential: Synergistic Effects of Solid SNEDDS and Lyophilized Solid Dispersion to Enhance Stability Attributes

open access: yesFrontiers in Bioscience, 2023
Background: Among lipid-based formulations, self-nanoemulsifying drug delivery systems (SNEDDS) have captured a spotlight, captivating both academia and the pharmaceutical industry.
Mohsin Kazi
exaly   +3 more sources

Development and optimization of Ropinirole loaded self-nanoemulsifying tablets

open access: yesFuture Journal of Pharmaceutical Sciences, 2023
Background The present research work aims to develop a Ropinirole-loaded self-Nanoemulsifying Drug Delivery system. Ropinirole has limited oral bioavailability due to substantial first-pass metabolism, which ultimately results in poor oral ...
Krunal Detholia   +4 more
doaj   +1 more source

Development and Evaluation of a Solid Self-Nanoemulsifying Drug Delivery System for Loratadin by Extrusion-Spheronization [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2014
Purpose: Recently the liquid nanoemulsifying drug delivery systems (SNEDDS) have shown dramatic effects on improving oral bioavailability of poorly soluble drugs.
Mohammadreza Abbaspour   +2 more
doaj   +1 more source

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