Results 41 to 50 of about 1,533,510 (152)

Combined Self-Nanoemulsifying and Solid Dispersion Systems Showed Enhanced Cinnarizine Release in Hypochlorhydria/Achlorhydria Dissolution Model

Pharmaceutics, 2021
The study aims to design a novel combination of drug-free solid self-nanoemulsifying drug delivery systems (S-SNEDDS) + solid dispersion (SD) to enhance cinnarizine (CN) dissolution at high pH environment caused by hypochlorhydria/achlorhydria.
Ahmad A. Shahba, Ahmad Y. Tashish, Fars K. Alanazi, Mohsin Kazi   +3 more
doaj   +1 more source

Understanding the effect of lipid formulation loading and ethanol as a diluent on solidification of pitavastatin super-saturable SNEDDS using factorial design approach

Research in Pharmaceutical Sciences, 2019
Solidification of a preconcentrate lipid formulation namely self-nano emulsifying drug delivery system (SNEDDS) is required to achieve feasibility, flexibility, and a new concept of “dry nano-emulsion”.
Ilham Kuncahyo, Syaiful Choiri, Achmad Fudholi, Abdul Rohman, Ronny Martien   +4 more
doaj   +1 more source

Formulation and Evaluation of Self-Nanoemulsifying Drug Delivery System Derived Tablet Containing Sertraline

Pharmaceutics, 2022
Being a biopharmaceutics classification system class II drug, the absorption of sertraline from the gut is mainly limited by its poor aqueous solubility.
Anroop B. Nair, Bhavna Singh, Jigar Shah, Shery Jacob, Bandar Aldhubiab, Nagaraja Sreeharsha, Mohamed A. Morsy, Katharigatta N. Venugopala, Mahesh Attimarad, Pottathil Shinu   +9 more
doaj   +1 more source

Non‐Aqueous Phospholipid Concentrates for Increasing the Bioavailability of Poorly Soluble Compounds

European Journal of Lipid Science and Technology, Volume 122, Issue 6, June 2020., 2020
In this review, the properties and use of liquid non‐aqueous phospholipid concentrates (NAPCs) are summarized. They are mainly used to solubilize poorly water‐soluble drug substances to enhance their oral bioavailability, but they also find applicability in dietetics and cosmetics.
Peter van Hoogevest
wiley   +1 more source

Solid Self-Nano Emulsifying Nanoplatform Loaded with Tamoxifen and Resveratrol for Treatment of Breast Cancer

Pharmaceutics, 2022
The solid self-nanoemulsifying drug delivery system (s-SNEDDS) is a growing platform for the delivery of drugs via oral route. In the present work, tamoxifen (TAM) was loaded in SNEDDS with resveratrol (RES), which is a potent chemotherapeutic ...
Nupur Shrivastava, Ankit Parikh, Rikeshwer Prasad Dewangan, Largee Biswas, Anita Kamra Verma, Saurabh Mittal, Javed Ali, Sanjay Garg, Sanjula Baboota   +8 more
doaj   +1 more source

Development of Guar Gum-Pectin-Based Colon Targeted Solid Self-Nanoemulsifying Drug Delivery System of Xanthohumol

Pharmaceutics, 2022
Present study deciphers development of oral polysaccharide-based colon targeted solid self-nanoemulsifying drug delivery system (S-SNEDDS) of xanthohumol (XH).
Mahesh Hanmantrao, Sourabh Chaterjee, Rajan Kumar, Sukriti Vishwas, Vancha Harish, Omji Porwal, Mohammed Alrouji, Othman Alomeir, Sharif Alhajlah, Monica Gulati, Gaurav Gupta, Kamal Dua, Sachin Kumar Singh   +12 more
doaj   +1 more source

How Climate Change Shapes Environmental, Social, and Governance (ESG) Performance in the MENA Countries

Sustainable Development, EarlyView.
ABSTRACT Climate change, political stability, and sustainability are three central factors that interact and serve as key drivers of achieving the Sustainable Development Goals (SDGs) in the MENA (Middle East and North Africa) region. Accordingly, this paper aims to fill a vital research gap by examining the impacts of climate change, natural resource ...
Hicham Ayad, Alanoud Al‐Maadid, Mohamed Sami Ben Ali   +2 more
wiley   +1 more source

Repurposing Butenafine as An Oral Nanomedicine for Visceral Leishmaniasis

Pharmaceutics, 2019
Leishmaniasis is a neglected tropical disease affecting more than 12 million people worldwide, which in its visceral clinical form (VL) is characterised by the accumulation of parasites in the liver and spleen, and can lead to death if not treated ...
Adriana Bezerra-Souza, Raquel Fernandez-Garcia, Gabriela F. Rodrigues, Francisco Bolas-Fernandez, Marcia Dalastra Laurenti, Luiz Felipe Passero, Aikaterini Lalatsa, Dolores R. Serrano   +7 more
doaj   +1 more source

Propolis‐Based Hybrid Nanoflowers as Multifunctional Nanozymes: Structural Integration of Polyphenols for Enhanced Catalytic and Antioxidant Activity

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
ABSTRACT Propolis is a polyphenol‐rich natural resin with well‐documented antioxidant activity; however, its practical application is restricted by poor aqueous solubility and limited stability. Herein, propolis‐based organic–inorganic hybrid nanoflowers (Prp‐Nfs) were synthesized by integrating a propolis extract into a Cu3(PO4)2·3H2O matrix under ...
Cevahir Altinkaynak, Fatih Kirmizikar
wiley   +1 more source

Comparison of Three Different Aqueous Microenvironments for Enhancing Oral Bioavailability of Sildenafil: Solid Self-Nanoemulsifying Drug Delivery System, Amorphous Microspheres and Crystalline Microspheres

International Journal of Nanomedicine, 2021
Jung Suk Kim,1,* Fakhar ud Din,2,* Sang Min Lee,1,* Dong Shik Kim,1 Mi Ran Woo,1 Seunghyun Cheon,1 Sang Hun Ji,1 Jong Oh Kim,3 Yu Seok Youn,4 Kyung Taek Oh,5 Soo-Jeong Lim,6 Sung Giu Jin,7 Han-Gon Choi1 1College of Pharmacy, Hanyang ...
Kim JS, Din FU, Lee SM, Kim DS, Woo MR, Cheon S, Ji SH, Kim JO, Youn YS, Oh KT, Lim SJ, Jin SG, Choi HG   +12 more
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