Results 51 to 60 of about 1,533,510 (152)

Optimization of a Beverage Using Mixture Design With Operational Variables

Journal of Engineering, Volume 2026, Issue 1, 2026.
The optimization of formulated products often requires simultaneous consideration of mixture composition and processing conditions, as both factors can strongly influence the final response. In this study, a mixture experimental design incorporating process variables was applied to the optimization of a prepared beverage (margarita), with the objective
Javier Cruz-Salgado, Sergio Alonso-Romero, Misaela Francisco Márquez, Uziel Mejía González, Himadri Majumder   +4 more
wiley   +1 more source

Development of docetaxel-loaded solid self-nanoemulsifying drug delivery system (SNEDDS) for enhanced chemotherapeutic effect

, 2013
The main purpose of this study was to investigate the potential of self-nano-emulsifying drug delivery system (SNEDDS) in improving the bioavailability of docetaxel (DCT) and its chemotherapeutic effect.
Marasini, Nirmal, Kim, Dong-Wuk, Kim, Jong Oh, Kim, Jeong Hwan, Choi, Han-Gon, Yong, Chul Soon, Kim, Jin Ki, Ramasamy, Thiruganesh, Oh, Yu-Kyoung, Seo, Youn Gee, Kim, Dae Hwan   +10 more
core   +1 more source

Self-nanoemulsifying drug delivery systems (SNEDDS) for oral delivery of Garcinia kola seeds ethanolic extract: formulation and in vivo antimalarial activity. [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2020
Context: Garcinia kola seeds are widely used in Congolese traditional medicine to treat uncomplicated malaria. While the ethanolic extract of these seeds (GK) is reputed for oral antimalarial activity, some of its constituents have shown poor water ...
Grady K. Mukubwa, Christian I. Nkanga, Aristote B. Buya, Jérémie K. Mbinze, Rui W.M. Krause, Patrick B. Memvanga   +5 more
doaj  

Development of Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization, In-Vitro, Ex-Vivo, and In-Vivo Evaluation

Nanomaterials, 2021
Hypertension is a cardiovascular disease that needs long-term medication. Oral delivery is the most common route for the administration of drugs. The present research is to develop piperine self-nanoemulsifying drug delivery system (PE-SNEDDS) using ...
Ameeduzzafar Zafar, Syed Sarim Imam, Nabil K. Alruwaili, Omar Awad Alsaidan, Mohammed H. Elkomy, Mohammed M. Ghoneim, Sultan Alshehri, Ahmed Mahmoud Abdelhaleem Ali, Khalid Saad Alharbi, Mohd Yasir, Kaveripakkam M. Noorulla, Sami I. Alzarea, Abdullah S. Alanazi   +12 more
doaj   +1 more source

Hemp Proteins Conjugated with Green Tea Polyphenol Extract Form De Novo Plant‐Sourced Emulsifiers Suitable for Nanodelivery Systems Bearing Lipophilic Psychopharmaceuticals

Advanced Therapeutics, Volume 8, Issue 11, November 2025.
Green tea polyphenols, conjugated either covalently or non‐covalently to hemp protein, comprise an excellent stabilizing matrix for oxidatively‐sensitive small molecules. These nanoemulsions are highly stable to a variety of chemical and physical stressors, protecting the small molecule while allowing for easy uptake across cell membranes and rapid ...
William Charles Hosie, Abhinandan Banerjee, Mary Augustina Egbuta, Kasra Razmkhah, Behzad Bolandi, Khalilalrahman Dehvari, Anton Homon, Aleena Kappadakunnel, Jonathan J. Simone, John F. Trant   +9 more
wiley   +1 more source

Innovative Self Nano‐Emulsifying Drug Delivery Systems for Peptic Ulcer Therapy: A Review

Particle &Particle Systems Characterization, Volume 42, Issue 1, January 2025.
SNEDDS improve bioavailability and solubility of poorly water‐soluble drugs, aiding in peptic ulcer treatment and regenerative healing. This innovative drug delivery bypasses side effects of conventional forms, utilizing biocompatible macromolecules to enhance solubility and promote healing. SNEDDS‐based systems show promise in boosting drug solubility
Syed Hassan Mujtaba, Rabia Arshad, Waqar Aman, Kashif Barkat, Abdul Malik, Anam Fatima, Salman Arshad Khan, Haleema Sadia, Gul e Maryam, Zeinab Moafian, Abbas Rahdar, M. Ali Aboudzadeh   +11 more
wiley   +1 more source

Optimasi Carrier Aerosil-200 pada Solid- SNEDDS dan Superdisintegran Croscarmellose Sodium pada FDT dalam Pembuatan Sediaan Kombinasi SNEDDS dan FDT dengan Model Bahan Aktif Nifedipin. [PDF]

, 2019
Kombinasi bentuk sediaan FDT dan sistem penghantaran SNEDDS mampu menghadirkan sistem baru yang dapat meningkatkan kelarutan obat dalam air serta mempercepat pelepasan dan absorbsi obat di dalam saluran pencernaan.
Putra, Ramendra Dirgantara
core  

SOLID SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) DEVOLOPMENT, APPLICATIONS AND FUTURE PERSPECTIVE: A REVIEW

, 2017
Developments in recent drug discovery programs, yields a large proportion of novel pharmacologically active molecules that are lipophilic and poorly soluble ,which is a major challenge for pharmaceutical researchers to enhance the oral bioavailability of
Febi S Kuruvila*, Flowerlet Mathew ,S Kuppuswamy
core   +1 more source

QbD‐Based Development of Self‐Nanoemulsifying Drug Delivery System for Codelivery of Simvastatin and Ezetimibe With Enhanced In Vitro Dissolution

Journal of Nanotechnology, Volume 2025, Issue 1, 2025.
Simvastatin and ezetimibe are antihyperlipidemic agents that exhibit synergistic therapeutic effects but have poor aqueous solubility, resulting in low and variable oral bioavailability. This study aimed to develop an optimized self‐nanoemulsifying drug delivery system (SNEDDS) for the codelivery of simvastatin and ezetimibe using a quality‐by‐design ...
Sani Ega Priani, Anis Yohana Chaerunisaa, Gofarana Wilar, Iyan Sopyan, Mozhgan Afshari   +4 more
wiley   +1 more source

Profil Ketoksikan Akut SNEDDS Propolis [PDF]

, 2022
Propolis memiliki efek imunostimulan yang tinggi namun tidak larut air dan memiliki bioavailabilitas yang rendah. Formulasi propolis dalam bentuk SNEDDS terbukti mampu meningkatkan aktivitas imunostimulannya, namun juga memberikan potensi ketoksikan ...
Hakim, Sherina Nabila Putri, Syukri, Yandi, Ramadani, Arba Pramundita, Fitria, Annisa   +3 more
core   +4 more sources