Results 71 to 80 of about 1,533,510 (152)

Review: Characterisation and Dissolution of Low Solubility Active Substances in S-SNEDDS Preparations with Various Manufacturing Methods

JPSCR: Journal of Pharmaceutical Science and Clinical Research
SNEDDS is composed of a drug, surfactants, co-surfactants, and oils. Developing and optimising the correct formulation is necessary to minimise time and expense, and ensure the correct formulation.
Rodhia Ulfa, Husnun Khairunnisa’ Pratiwi   +1 more
doaj   +1 more source

A Thermoresponsive In Situ Salified Self-Nanoemulsifying Drug Delivery System of Olmesartan Medoxomil: Overcoming Leakage and Drug Trapping Limitations

Pharmaceutics
Background/Objectives: Solid self-nanoemulsifying drug delivery systems (SNEDDS) prepared by adsorption onto porous carriers are widely used to improve the oral delivery of poorly water-soluble drugs. However, this approach is limited by increased dosing
Abdelrahman Y. Sherif, Mohammad A. Altamimi, Ehab M. Elzayat   +2 more
doaj   +1 more source

Custom fractional factorial designs to develop atorvastatin self-nanoemulsifying and nanosuspension delivery systems – enhancement of oral bioavailability

Drug Design, Development and Therapy, 2015
Fahima M Hashem,1 Majid M Al-Sawahli,2 Mohamed Nasr,1 Osama AA Ahmed3,4 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Helwan University, Cairo, Egypt; 2Holding Company for Biological Products and Vaccines (VACSERA ...
Hashem FM, Al-Sawahli MM, Nasr M, Ahmed OA   +3 more
doaj  

Dissolution improvement of solid self-emulsifying drug delivery systems of fenofi brate using an inorganic high surface adsorption material

Acta Pharmaceutica, 2015
Solidification of lipid formulations using adsorbents is a recent technique attracting great interest due to its favourable properties including flexibility in dose division, reduction of intra-subject and inter-subject variability, improvement in ...
Shazly Gamal, Mohsin Kazi
doaj   +1 more source

Formulation and Characterization of Solid Self Nano Emulsifying Drug Delivery System (S-SNEDDS) Loading Curcuma xanthorrhiza Extract

Curcuma xanthorrhiza has an active component xanthorrhizol that is poorly soluble in water, resulting in limited absorption and bioavailability. Liquid Self Nano Emulsifying Drug Delivery System (SNEDDS) dosage formulations can improve its solubility and
Taher, Muhammad, Syukri, Yandi, Seran, Yuvina, Ramadhani, Arba Pramundita, Hannie Fitriani   +4 more
core   +1 more source

The Impact of Polymers on Enzalutamide Solid Self-Nanoemulsifying Drug Delivery System and Improved Bioavailability

Pharmaceutics
Enzalutamide (ENZ), marketed under the brand name Xtandi® as a soft capsule, is an androgen receptor signaling inhibitor drug actively used in clinical settings for treating prostate cancer. However, ENZ’s low solubility and bioavailability significantly
Su-Min Lee, Jeong-Gyun Lee, Tae-Han Yun, Chul-Ho Kim, Jung-Hyun Cho, Kyeong-Soo Kim   +5 more
doaj   +1 more source

Possible SNEDDS Formulations of Aripiprazole and Escitalopram

Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) have emerged as promising platforms to enhance the solubility and oral bioavailability of poorly water-soluble drugs.
Akshita Agrawal, Pooja Rani, Rimpy Pahwa, Samridhi Thakral, Sandeep Arora   +4 more
core   +1 more source

Evaluating Various Lactose Types as Solid Carriers for Improving Curcumin Solubility in Solid Self-Nanoemulsifying Drug Delivery Systems (S-SNEDDSs) for Oral Administration

Sci
Curcumin, a bioactive compound derived from turmeric, possesses numerous pharmaceutical properties; however, its poor aqueous solubility and permeability result in low bioavailability. This study aims to develop a solid self-nanoemulsifying drug delivery
Panida Teerapipattanapong, Pimrada Jaikon, Nichapa Ningsanonda, Etsuo Yonemochi, Takayuki Furuishi, Namon Hirun, Pakorn Kraisit   +6 more
doaj   +1 more source

ePoster

European Journal of Neurology, Volume 32, Issue S1, June 2025.
wiley   +1 more source

Solidification Techniques and Polymers Used in Converting Liquid Snedds to Solid Snedds: a Comprehensive Review

Enhancing the oral bioavailability of poorly water-soluble, lipophilic drug molecules remains a major challenge for pharmaceutical scientists, as modern drug discovery programs increasingly yield compounds with low aqueous solubility and high ...
KHAN, KASHAF, AIN, QURRATUL, AIN, SHABNAM, KUMAR, BABITA   +3 more
core