Results 31 to 40 of about 19,689,673 (253)

WarmStart colorimetric loop-mediated isothermal amplification for the one-tube, contamination-free and visualization detection of Shigella flexneri

International Journal of Infectious Diseases, 2021
Objectives: Shigella flexneri (S. flexneri) is prevalent worldwide and the most common Shigella in many countries, causing highly contagious diarrhea, which seriously threatens public health.
Yaoqiang Shi, Min Xu, Xiaoqiong Duan, Shilin Li, Jia-wei Ding, Limin Chen   +5 more
doaj   +1 more source

Shigella flexneri infection in Caenorhabditis elegans: cytopathological examination and identification of host responses. [PDF]

PLoS ONE, 2014
The Gram-negative bacterium Shigella flexneri is the causative agent of shigellosis, a diarrhoeal disease also known as bacillary dysentery. S. flexneri infects the colonic and rectal epithelia of its primate host and induces a cascade of inflammatory ...
Divya T George, Carolyn A Behm, David H Hall, Ulrike Mathesius, Melanie Rug, Ken C Q Nguyen, Naresh K Verma   +6 more
doaj   +1 more source

Clonal serotype 1c multidrug-resistant Shigella flexneri detected in multiple institutions by sentinel-site sequencing

Frontiers in Medicine, 2022
Shigella flexneri is a major diarrhoeal pathogen, and the emergence of multidrug-resistant S. flexneri is of public health concern. We report the detection of a clonal cluster of multidrug-resistant serotype 1c (7a) S. flexneri in Singapore in April 2022.
Karrie K. K. Ko, Karrie K. K. Ko, Karrie K. K. Ko, Karrie K. K. Ko, Karrie K. K. Ko, Joash Jun Keat Chu, Kar Mun Lim, Hatairat Yingtaweesittikul, Wenjie Huang, Wenjie Huang, Shireen Yan Ling Tan, Shireen Yan Ling Tan, Kenneth Choon Meng Goh, Kenneth Choon Meng Goh, Si Huei Tan, Tong Yong Ng, Matthias Maiwald, Matthias Maiwald, Matthias Maiwald, Jonathan Wei Zhong Chia, Delphine Yanhong Cao, Yen Ee Tan, Yen Ee Tan, James Heng Chiak Sim, James Heng Chiak Sim, Tse Hsien Koh, Tse Hsien Koh, Niranjan Nagarajan, Chayaporn Suphavilai   +28 more
doaj   +1 more source

The Chemical Structure Properties and Promoting Biofilm Activity of Exopolysaccharide Produced by Shigella flexneri

Frontiers in Microbiology, 2022
Shigella flexneri is a waterborne and foodborne pathogen that can damage human health. The exopolysaccharides (S-EPS) produced by S. flexneri CMCC51574 were found to promote biofilm formation and virulence. In this research, the crude S-EPS produced by S.
Yinglong Song, Fenglian Ma, Mengying Sun, Guangqing Mu, Guangqing Mu, Yanfeng Tuo   +5 more
doaj   +1 more source

The effect of the potential PhoQ histidine kinase inhibitors on Shigella flexneri virulence. [PDF]

PLoS ONE, 2011
PhoQ/PhoP is an important two-component system that regulates Shigella virulence. We explored whether the PhoQ/PhoP system is a promising target for new antibiotics against S. flexneri infection.
Xia Cai, Jian Zhang, Mingliang Chen, Yang Wu, Xueqing Wang, Jiayu Chen, Junqin Zhang, Xu Shen, Di Qu, Hualiang Jiang   +9 more
doaj   +1 more source

Characterisation of early mucosal and neuronal lesions following Shigella flexneri infection in human colon. [PDF]

PLoS ONE, 2009
BACKGROUND: Shigella, an enteroinvasive bacteria induces a major inflammatory response responsible for acute rectocolitis in humans. However, early effect of Shigella flexneri (S.
Emmanuel Coron, Mathurin Flamant, Philippe Aubert, Thilo Wedel, Thierry Pedron, Eric Letessier, Jean P Galmiche, Philippe J Sansonetti, Michel Neunlist   +8 more
doaj   +1 more source

Characterization of a serologically atypical Shigella flexneri Z isolated from diarrheal patients in Bangladesh and a proposed serological scheme for Shigella flexneri. [PDF]

PLoS ONE, 2018
BACKGROUND:Atypical Shigella flexneri Z variant, that agglutinate with E1037 group factor specific monoclonal antisera against Shigella flexneri IV-I but not with other group or type specific antisera, has continuously being isolated in Bangladesh since ...
Mohammad Shahnaij, Hasan A Latif, Ishrat J Azmi, Mohammed Badrul Amin, Sharmin J Luna, Mohammad Aminul Islam, Kaisar Ali Talukder   +6 more
doaj   +1 more source

Evolutionary and genomic insights into the long-term colonization of Shigella flexneri in animals

Emerging Microbes and Infections, 2022
The enteroinvasive bacterium Shigella flexneri is known as a highly host-adapted human pathogen. There had been no known other reservoirs reported until recently. Here 34 isolates obtained from animals (yaks, dairy cows and beef cattle) from 2016 to 2017
Junrong Liang, Zhen Zhu, Ruiting Lan, Jing Meng, Bram Vrancken, Shan Lu, Dong Jin, Jing Yang, Jianping Wang, Tian Qin, Ji Pu, Li Zhang, Kui Dong, Mingchao Xu, Huaiyu Tian, Taijiao Jiang, Jianguo Xu   +16 more
doaj   +1 more source

Shigella hijacks the exocyst to cluster macropinosomes for efficient vacuolar escape.

PLoS Pathogens, 2020
Shigella flexneri invades host cells by entering within a bacteria-containing vacuole (BCV). In order to establish its niche in the host cytosol, the bacterium ruptures its BCV. Contacts between S.
Yuen-Yan Chang, Virginie Stévenin, Magalie Duchateau, Quentin Giai Gianetto, Veronique Hourdel, Cristina Dias Rodrigues, Mariette Matondo, Norbert Reiling, Jost Enninga   +8 more
doaj   +1 more source

Phylogenetic Characterization Reveals Prevalent Shigella flexneri ST100 Clone in Beijing, China, 2005 to 2018

mSphere, 2020
Shigella flexneri is a major cause of bacillary dysentery in Beijing, China. The genetic features and population structure of locally circulating clones remained unclear. In this study, we sequenced the genomes of 93 S. flexneri isolates from patients in
Lang Yang, Bing Lü, Quanyi Wang, Kaiying Wang, Yanfeng Lin, Chaojie Yang, Shaofu Qiu, Peng Li, Hongbin Song   +8 more
doaj   +3 more sources