Results 51 to 60 of about 19,689,673 (253)

Shigella flexneri utilize the spectrin cytoskeleton during invasion and comet tail generation [PDF]

, 2012
Background The spectrin cytoskeleton is emerging as an important host cell target of enteric bacterial pathogens. Recent studies have identified a crucial role for spectrin and its associated proteins during key pathogenic processes of Listeria ...
Tyson J Ruetz, Ann E Lin, Julian A Guttman   +2 more
core   +2 more sources

Shigella Flexneri Serotypes: O-antigen Structure, Serotype Conversion, and Serotyping Methods

Oman Medical Journal, 2023
Shigella flexneri is the most common cause of shigellosis in developing countries. Up to now, 23 serotypes of S. flexneri have been reported. Different serotypes result from the addition of acetyl, glucosyl, or phosphatidylethanolamine groups on the O ...
Mehrzad Sadredinamin, Sajjad Yazdansetad, Masoud Alebouyeh, Mohammad Mahdi Karimi Yazdi, Zohreh Ghalavand   +4 more
doaj   +1 more source

Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance Shigella flexneri, a deleterious bacterium, causes massive human infection cases and deaths worldwide. To facilitate survival and replication in infected host cells, S. flexneri can secrete two highly similar E3 ligase effectors, IpaH1.4 and
Jianping Liu, Yaru Wang, Danni Wang, Yingli Wang, Xiaolong Xu, Yuchao Zhang, Ying Li, Mingfang Zhang, Xinyu Gong, Yubin Tang, Li-Qiang Shen, Miao Li, L. Pan   +12 more
semanticscholar   +1 more source

The emergence and fate of horizontally acquired genes in Escherichia coli [PDF]

, 2008
Bacterial species, and even strains within species, can vary greatly in their gene contents and metabolic capabilities. We examine the evolution of this diversity by assessing the distribution and ancestry of each gene in 13 sequenced isolates of ...
Marri, P.R., Ochman, H., Passel, M.W.J., van   +2 more
core   +4 more sources

How to rewire the host cell: A home improvement guide for intracellular bacteria. [PDF]

, 2017
Intracellular bacterial pathogens have developed versatile strategies to generate niches inside the eukaryotic cells that allow them to survive and proliferate.
Cornejo, Elias, Mukherjee, Shaeri, Schlaermann, Philipp   +2 more
core   +2 more sources

Prevalence of Plasmid-Mediated Determinants With Decreased Susceptibility to Azithromycin Among Shigella Isolates in Anhui, China

Frontiers in Microbiology, 2020
ObjectiveThe aims of this study were to describe azithromycin (AZM) susceptibility patterns among Shigella isolates in Anhui, China and identify predictors of resistance with mobile element-mediated genes.MethodsA total of 517 non-duplicate Shigella ...
Yanyan Liu, Yanyan Liu, Yanyan Liu, Hongru Li, Na Lv, Yalong Zhang, Xihai Xu, Ying Ye, Ying Ye, Ying Ye, Yufeng Gao, Yufeng Gao, Yufeng Gao, Jiabin Li, Jiabin Li, Jiabin Li, Jiabin Li   +16 more
doaj   +1 more source

Expression of bacterial virulence factors and cytokines during in vitro macrophage infection by enteroinvasive Escherichia coli and Shigella flexneri: a comparative study [PDF]

, 2010
Enteroinvasive Escherichia coli (EIEC) and Shigellaspp cause bacillary dysentery in humans by invading and multiplying within epithelial cells of the colonic mucosa.
ALBUQUERQUE, José AT, AMHAZ, Juliana MK, BANDO, Silvia Y, MARTINEZ, Marina B, MOREIRA-FILHO, Carlos A, MORENO, Ana CR   +5 more
core   +3 more sources

A Pentavalent Shigella flexneri LPS-Based Vaccine Candidate Is Safe and Immunogenic in Animal Models

Vaccines, 2023
A multivalent vaccine is much needed to achieve protection against predominant Shigella serotypes. Recently, we demonstrated the clinical applicability and immunogenic potential of tri-acylated S. flexneri 2a lipopolysaccharide (Ac3-S-LPS).
Vladimir A. Ledov, Marina E. Golovina, Biana I. Alkhazova, Vyacheslav L. Lvov, Alexander L. Kovalchuk, Petr G. Aparin   +5 more
doaj   +1 more source

The type three secretion system effector protein IpgB1 promotes Shigella flexneri cell-to-cell spread through double-membrane vacuole escape

PLoS Pathogens, 2022
S. flexneri is an important human pathogen that causes bacillary dysentery. During infection, S. flexneri invades colonic epithelial cells, hijacks the host cell cytoskeleton to move in the cytosol of infected cells, and spreads from cell to cell through
Erin Weddle, Volkan K Köseoğlu, Brittany A DeVasure, H. Agaisse   +3 more
semanticscholar   +1 more source

Characterization of an emergent clone of enteroinvasive Escherichia coli circulating in Europe [PDF]

, 2016
Enteroinvasive Escherichia coli (EIEC) cause intestinal illness indistinguishable from that caused by Shigella, mainly in developing countries. Recently an upsurge of cases of EIEC infections has been observed in Europe, with two large outbreaks ...
Caprioli, A., Dallman, T., Herrera León, S., Jenkins, C., Maugliani, A., Michelacci, V, Morabito, S., PROSSEDA, Gianni, Sanchez, S., Tozzoli, R.   +9 more
core   +1 more source